fluorouracil has been researched along with Salivary Gland Diseases in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Salivary Gland Diseases: Diseases involving the SALIVARY GLANDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-five patients diagnosed with colon cancer at an initial, intermediate and late phase submitted to specifically devised therapy were assessed." | 1.35 | Oral signs of intravenous chemotherapy with 5-Fluorouracil and Leucovorin calcium in colon cancer treatment. ( Busamia, BE; Campos, ML; Dubersarsky, C; Finkelberg, AB; Jarchum, G; Lavarda, M; Linares, JA; Mazzeo, MA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazzeo, MA | 1 |
| Linares, JA | 1 |
| Campos, ML | 1 |
| Busamia, BE | 1 |
| Dubersarsky, C | 1 |
| Lavarda, M | 1 |
| Jarchum, G | 1 |
| Finkelberg, AB | 1 |
| Parker, GA | 1 |
2 other studies available for fluorouracil and Salivary Gland Diseases
| Article | Year |
|---|---|
Oral signs of intravenous chemotherapy with 5-Fluorouracil and Leucovorin calcium in colon cancer treatment.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Female; Fluorouracil; Humans; Infus | 2009 |
Re: Article by Ewens et al. entitled, "Fluorouracil plus leucovorin induces submandibular salivary gland enlargement in rats".
Topics: Animals; Antidotes; Antimetabolites; Coronavirus Infections; Fluorouracil; Leucovorin; Rats; Salivar | 2005 |