fluorouracil has been researched along with Rupture in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Rupture: Forcible or traumatic tear or break of an organ or other soft part of the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The formation of adhesions and the leukocytosis on the anastomoses were significantly higher in the 2nd, 3rd and 4th group than in the 1st group (P < 0." | 1.37 | The effects of the intraperitoneal administration of oxaliplatin and 5-FU on the healing of colonic anastomoses: an experimental study. ( Despoudi, K; Kanellos, D; Koliakos, G; Lazaridis, H; Mantzoros, I; Pramateftakis, MG; Raptis, D; Zacharakis, E; Zaraboukas, T, 2011) |
| " Animals in Groups III and IV received the same drug dosage for six weeks and were operated at different intervals: Group III at one week and Group IV at two weeks after completion of chemotherapy." | 1.29 | Effect of 5-fluorouracil and leucovorin on the integrity of colonic anastomoses in the rat. ( Gordon, PH; Hananel, N, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pramateftakis, MG | 2 |
| Kanellos, D | 2 |
| Mantzoros, I | 2 |
| Despoudi, K | 2 |
| Raptis, D | 2 |
| Angelopoulos, S | 1 |
| Koliakos, G | 2 |
| Zaraboukas, T | 2 |
| Lazaridis, C | 1 |
| Zacharakis, E | 1 |
| Lazaridis, H | 1 |
| Colucci, G | 1 |
| Thaler, W | 1 |
| Dejaco, H | 1 |
| Marsoner, H | 1 |
| Grones, A | 1 |
| Sundqvist, K | 1 |
| Hafström, L | 1 |
| Jönsson, PE | 1 |
| Lunderquist, A | 1 |
| Nowak, E | 1 |
| Hananel, N | 1 |
| Gordon, PH | 1 |
| Lai, MM | 1 |
| Haller, JA | 1 |
| Davis, G | 1 |
1 review available for fluorouracil and Rupture
| Article | Year |
|---|---|
Colonic rupture in a patient on combination chemotherapy for metastasized carcinoma of the esophagogastric junction. Case report and review of the literature.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cecal Diseases; Cisplatin; Colonic D | 2005 |
6 other studies available for fluorouracil and Rupture
| Article | Year |
|---|---|
Intraperitoneally administered irinotecan with 5-fluorouracil impair wound healing of colonic anastomoses in a rat model: an experimental study.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Antimetabolites, Antineoplastic; Antineoplastic Ag | 2011 |
The effects of the intraperitoneal administration of oxaliplatin and 5-FU on the healing of colonic anastomoses: an experimental study.
Topics: Anastomosis, Surgical; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Colon; Fluor | 2011 |
Upper G-I bleeding following intraarterial chemotherapy infusion.
Topics: Arteries; Catheters, Indwelling; Duodenal Ulcer; Duodenum; Female; Fluorouracil; Gastrointestinal He | 1983 |
Effect of 5-fluorouracil and leucovorin on the integrity of colonic anastomoses in the rat.
Topics: Anastomosis, Surgical; Animals; Colectomy; Colon; Disease Models, Animal; Fluorouracil; Injections, | 1995 |
Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil.
Topics: Adult; Anterior Chamber; Antimetabolites; Corneal Diseases; Epithelial Cells; Eye Injuries; Fluorour | 2002 |
Pseudomyxoma peritonei and the appendix.
Topics: Adult; Appendiceal Neoplasms; Cystadenoma; Fluorouracil; Humans; Male; Mucocele; Omentum; Peritoneal | 1970 |