fluorouracil has been researched along with Rupture, Spontaneous in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Use of chlorhexidine intraperitoneal therapy at the time of the operation for perforated colorectal cancer significantly decreases the frequency of gross tumor recurrence but not total recurrences." | 3.69 | Use of intraperitoneal 5-fluorouracil and chlorhexidine for prevention of recurrence of perforated colorectal carcinoma in a rat model. ( Ong, J; Stabile, B; Stamos, M; Stuntz, M; Wilmoth, G, 1997) |
| "Hydroxyproline levels were significantly increased with the use of HBO2 in rats, independent of chemotherapy administration." | 1.32 | Effect of hyperbaric oxygen on anastomoses created under the influence of 5-FU. ( Akin, ML; Celenk, T; Emeksiz, S; Erenoğlu, C; Foley, E; Uluutku, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fuccio, L | 1 |
| Cennamo, V | 1 |
| Erenoğlu, C | 1 |
| Uluutku, H | 1 |
| Emeksiz, S | 1 |
| Akin, ML | 1 |
| Foley, E | 1 |
| Celenk, T | 1 |
| Stuntz, M | 1 |
| Wilmoth, G | 1 |
| Ong, J | 1 |
| Stabile, B | 1 |
| Stamos, M | 1 |
| Chan, KL | 1 |
| Tam, PK | 1 |
| Kanellos, I | 1 |
| Odisseos, C | 1 |
| Kazantzidou, D | 1 |
| Galovatsea, K | 1 |
| Zaraboukas, T | 1 |
| Dadoukis, I | 1 |
| Horton, J | 1 |
| Brickner, TJ | 1 |
| Illig, WP | 1 |
| Self, J | 1 |
| Thompson, CT | 1 |
| Jochimsen, PR | 1 |
| Zike, WL | 1 |
| Shirazi, SS | 1 |
| Pearlman, NW | 1 |
1 review available for fluorouracil and Rupture, Spontaneous
| Article | Year |
|---|---|
Progress in treatment of cancer of the large bowel.
Topics: Antineoplastic Agents; Colonic Neoplasms; Fluorouracil; Follow-Up Studies; Humans; Intestinal Obstru | 1976 |
6 other studies available for fluorouracil and Rupture, Spontaneous
| Article | Year |
|---|---|
Bevacizumab-based therapy and complication risk after colonic stent placement: is it time for a warning?
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic C | 2010 |
Effect of hyperbaric oxygen on anastomoses created under the influence of 5-FU.
Topics: Anastomosis, Surgical; Animals; Antimetabolites, Antineoplastic; Colon; Fluorouracil; Hydroxyproline | 2003 |
Use of intraperitoneal 5-fluorouracil and chlorhexidine for prevention of recurrence of perforated colorectal carcinoma in a rat model.
Topics: Animals; Anti-Infective Agents, Local; Antimetabolites, Antineoplastic; Chlorhexidine; Colorectal Ne | 1997 |
Successful right trisegmentectomy for ruptured hepatoblastoma with preoperative transcatheter arterial embolization.
Topics: Angiography; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Embo | 1998 |
Effect of early versus delayed postoperative injection of 5-fluorouracil plus interferon-alpha on colonic healing.
Topics: Anastomosis, Surgical; Animals; Colon; Drug Administration Schedule; Fluorouracil; Interferon alpha- | 1998 |
Iatrogenic liver abscesses. A complication of hepatic artery ligation for tumor.
Topics: Arteriovenous Shunt, Surgical; Biliary Fistula; Bronchial Fistula; Female; Fluorouracil; Hepatic Art | 1978 |