fluorouracil has been researched along with Rift Valley Fever in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Rift Valley Fever: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A live attenuated vaccine virus variant of Rift Valley fever (RVF) virus was developed by passaging a human isolate in tissue culture under the influence of the mutagen 5-fluorouracil." | 3.68 | Ability of a mutagenized virus variant to protect young lambs from Rift Valley fever. ( Baskerville, A; Hubbard, KA; Stephenson, JR, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hubbard, KA | 1 |
| Baskerville, A | 1 |
| Stephenson, JR | 1 |
1 other study available for fluorouracil and Rift Valley Fever
| Article | Year |
|---|---|
Ability of a mutagenized virus variant to protect young lambs from Rift Valley fever.
Topics: Animals; Fluorouracil; Humans; Liver Diseases; Rift Valley Fever; Rift Valley fever virus; Sheep; Sh | 1991 |