fluorouracil has been researched along with Retroviridae Infections in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Retroviridae Infections: Virus diseases caused by the RETROVIRIDAE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bodine, DM | 1 |
| McDonagh, KT | 1 |
| Seidel, NE | 1 |
| Nienhuis, AW | 1 |
| Keller, G | 2 |
| Snodgrass, R | 2 |
3 other studies available for fluorouracil and Retroviridae Infections
| Article | Year |
|---|---|
Survival and retrovirus infection of murine hematopoietic stem cells in vitro: effects of 5-FU and method of infection.
Topics: Animals; Base Sequence; Beta-Globulins; Bone Marrow Cells; Cell Survival; Cells, Cultured; Female; F | 1991 |
Life span of multipotential hematopoietic stem cells in vivo.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Culture Techniques; Embryo, | 1990 |
Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.
Topics: Animals; Clone Cells; Colony-Forming Units Assay; Embryo, Mammalian; Fluorouracil; Hematopoiesis; He | 1987 |