fluorouracil has been researched along with Respiratory Insufficiency in 13 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Squamous cell carcinoma was an adverse factor related to increased postoperative pulmonary complications." | 1.36 | High-dose preoperative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications: correlation with dose-volume histogram parameters. ( Hurmuzlu, M; Muren, LP; Smaaland, R; Viste, A; Wentzel-Larsen, T; Øvrebø, K, 2010) |
| "Progressive respiratory failure developed in a 68 year-old female who was treated with single-agent oxaliplatin for colorectal cancer." | 1.33 | Interstitial pneumonitis after oxaliplatin treatment in colorectal cancer. ( Colomer, R; Fabregat, MB; Merino, BQ; Puig, J; Soy, E; Yagüe, XH, 2005) |
| "This case suggested that respiratory failure due to lymphangitis carcinomatosis can be a treatable condition." | 1.29 | Respiratory failure due to pulmonary lymphangitis carcinomatosis. ( Fujita, J; Kubo, A; Takahara, J; Takigawa, K; Yamagishi, Y; Yamaji, Y, 1993) |
| "Pathology of the optic nerves revealed demyelination." | 1.29 | Ocular toxicity following high dose chemotherapy and autologous transplant. ( Elkordy, M; Hulette, C; Hussein, A; Jaffe, GJ; Khawly, JA; Peters, WP; Rubin, P; Vredenburgh, JJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kadikoylu, G | 1 |
| Barutca, S | 1 |
| Tataroglu, C | 1 |
| Kafkas, S | 1 |
| Erpek, H | 1 |
| Meydan, N | 1 |
| Yavasoglu, I | 1 |
| Bolaman, Z | 1 |
| Bercovitz, RS | 1 |
| Greffe, BS | 1 |
| Hunger, SP | 1 |
| Otrock, ZK | 1 |
| Barada, WM | 1 |
| Sawaya, RA | 1 |
| Saab, JF | 1 |
| Bazarbachi, AA | 1 |
| García-Montesinos-De la Peña, M | 1 |
| Oteiza-López, L | 1 |
| Aldunate-Calvo, S | 1 |
| Gómez-Sánchez, MJ | 1 |
| Sáenz-Bañuelos, JJ | 1 |
| Tihista-Jiménez, JA | 1 |
| Hurmuzlu, M | 1 |
| Øvrebø, K | 1 |
| Wentzel-Larsen, T | 1 |
| Muren, LP | 1 |
| Viste, A | 1 |
| Smaaland, R | 1 |
| Watkins, J | 1 |
| Slade, JH | 1 |
| Phan, A | 1 |
| Eng, C | 1 |
| Weissferdt, A | 1 |
| Overman, MJ | 1 |
| Brunetti, G | 1 |
| Delmastro, M | 1 |
| Poggi, G | 1 |
| Avanza, F | 1 |
| Bertoli, G | 1 |
| Yagüe, XH | 1 |
| Soy, E | 1 |
| Merino, BQ | 1 |
| Puig, J | 1 |
| Fabregat, MB | 1 |
| Colomer, R | 1 |
| Nixon, DW | 1 |
| Shlaer, SM | 1 |
| Fujita, J | 1 |
| Yamagishi, Y | 1 |
| Kubo, A | 1 |
| Takigawa, K | 1 |
| Yamaji, Y | 1 |
| Takahara, J | 1 |
| Rubin, P | 1 |
| Hulette, C | 1 |
| Khawly, JA | 1 |
| Elkordy, M | 1 |
| Hussein, A | 1 |
| Vredenburgh, JJ | 1 |
| Jaffe, GJ | 1 |
| Peters, WP | 1 |
| Snimshchikov, VA | 1 |
| Korman, DB | 1 |
| Degner, RA | 1 |
| Kerley, SW | 1 |
| McGregor, DH | 1 |
| Dixon, AY | 1 |
13 other studies available for fluorouracil and Respiratory Insufficiency
| Article | Year |
|---|---|
Thrombotic thrombocytopenic purpura as the first manifestation of metastatic adenocarcinoma in a young woman.
Topics: Abdomen, Acute; Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Bio | 2010 |
Acute tumor lysis syndrome in a 7-month-old with hepatoblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disseminated Intravascular Coagulation; F | 2010 |
Bilateral phrenic nerve paralysis as a manifestation of paraneoplastic syndrome.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C | 2010 |
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B | 2010 |
High-dose preoperative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications: correlation with dose-volume histogram parameters.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi-Square Di | 2010 |
Fatal diffuse alveolar damage associated with oxaliplatin administration.
Topics: Acute Lung Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fatal Ou | 2011 |
Sudden improvement of respiratory failure in a woman with carcinoma of the colon.
Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Bronchial Neoplasms; Colonic Neopla | 2002 |
Interstitial pneumonitis after oxaliplatin treatment in colorectal cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Chemothera | 2005 |
Fulminant lung metastases from cancer of the breast.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorour | 1981 |
Respiratory failure due to pulmonary lymphangitis carcinomatosis.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Fluorouracil; | 1993 |
Ocular toxicity following high dose chemotherapy and autologous transplant.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cispl | 1996 |
[Respiratory arrest following 5-fluorouracil administration].
Topics: Aged; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Muscle Relaxation; Respiratory Ins | 1992 |
Metastatic basal cell carcinoma: report of a case presenting with respiratory failure.
Topics: Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Neopla | 1991 |