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fluorouracil and Respiratory Insufficiency

fluorouracil has been researched along with Respiratory Insufficiency in 13 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Squamous cell carcinoma was an adverse factor related to increased postoperative pulmonary complications."1.36High-dose preoperative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications: correlation with dose-volume histogram parameters. ( Hurmuzlu, M; Muren, LP; Smaaland, R; Viste, A; Wentzel-Larsen, T; Øvrebø, K, 2010)
"Progressive respiratory failure developed in a 68 year-old female who was treated with single-agent oxaliplatin for colorectal cancer."1.33Interstitial pneumonitis after oxaliplatin treatment in colorectal cancer. ( Colomer, R; Fabregat, MB; Merino, BQ; Puig, J; Soy, E; Yagüe, XH, 2005)
"This case suggested that respiratory failure due to lymphangitis carcinomatosis can be a treatable condition."1.29Respiratory failure due to pulmonary lymphangitis carcinomatosis. ( Fujita, J; Kubo, A; Takahara, J; Takigawa, K; Yamagishi, Y; Yamaji, Y, 1993)
"Pathology of the optic nerves revealed demyelination."1.29Ocular toxicity following high dose chemotherapy and autologous transplant. ( Elkordy, M; Hulette, C; Hussein, A; Jaffe, GJ; Khawly, JA; Peters, WP; Rubin, P; Vredenburgh, JJ, 1996)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kadikoylu, G1
Barutca, S1
Tataroglu, C1
Kafkas, S1
Erpek, H1
Meydan, N1
Yavasoglu, I1
Bolaman, Z1
Bercovitz, RS1
Greffe, BS1
Hunger, SP1
Otrock, ZK1
Barada, WM1
Sawaya, RA1
Saab, JF1
Bazarbachi, AA1
García-Montesinos-De la Peña, M1
Oteiza-López, L1
Aldunate-Calvo, S1
Gómez-Sánchez, MJ1
Sáenz-Bañuelos, JJ1
Tihista-Jiménez, JA1
Hurmuzlu, M1
Øvrebø, K1
Wentzel-Larsen, T1
Muren, LP1
Viste, A1
Smaaland, R1
Watkins, J1
Slade, JH1
Phan, A1
Eng, C1
Weissferdt, A1
Overman, MJ1
Brunetti, G1
Delmastro, M1
Poggi, G1
Avanza, F1
Bertoli, G1
Yagüe, XH1
Soy, E1
Merino, BQ1
Puig, J1
Fabregat, MB1
Colomer, R1
Nixon, DW1
Shlaer, SM1
Fujita, J1
Yamagishi, Y1
Kubo, A1
Takigawa, K1
Yamaji, Y1
Takahara, J1
Rubin, P1
Hulette, C1
Khawly, JA1
Elkordy, M1
Hussein, A1
Vredenburgh, JJ1
Jaffe, GJ1
Peters, WP1
Snimshchikov, VA1
Korman, DB1
Degner, RA1
Kerley, SW1
McGregor, DH1
Dixon, AY1

Other Studies

13 other studies available for fluorouracil and Respiratory Insufficiency

ArticleYear
Thrombotic thrombocytopenic purpura as the first manifestation of metastatic adenocarcinoma in a young woman.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2010, Volume: 42, Issue:1

    Topics: Abdomen, Acute; Adenocarcinoma, Mucinous; Adult; Antineoplastic Combined Chemotherapy Protocols; Bio

2010
Acute tumor lysis syndrome in a 7-month-old with hepatoblastoma.
    Current opinion in pediatrics, 2010, Volume: 22, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disseminated Intravascular Coagulation; F

2010
Bilateral phrenic nerve paralysis as a manifestation of paraneoplastic syndrome.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:2

    Topics: Adenocarcinoma; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined C

2010
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
    Medicina intensiva, 2010, Volume: 34, Issue:2

    Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B

2010
High-dose preoperative chemoradiotherapy in esophageal cancer patients does not increase postoperative pulmonary complications: correlation with dose-volume histogram parameters.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi-Square Di

2010
Fatal diffuse alveolar damage associated with oxaliplatin administration.
    Clinical colorectal cancer, 2011, Volume: 10, Issue:3

    Topics: Acute Lung Injury; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Fatal Ou

2011
Sudden improvement of respiratory failure in a woman with carcinoma of the colon.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2002, Volume: 57, Issue:1

    Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Bronchial Neoplasms; Colonic Neopla

2002
Interstitial pneumonitis after oxaliplatin treatment in colorectal cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2005, Volume: 7, Issue:11

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Chemothera

2005
Fulminant lung metastases from cancer of the breast.
    Medical and pediatric oncology, 1981, Volume: 9, Issue:4

    Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclophosphamide; Female; Fluorour

1981
Respiratory failure due to pulmonary lymphangitis carcinomatosis.
    Chest, 1993, Volume: 103, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Fluorouracil;

1993
Ocular toxicity following high dose chemotherapy and autologous transplant.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Cispl

1996
[Respiratory arrest following 5-fluorouracil administration].
    Voprosy onkologii, 1992, Volume: 38, Issue:11

    Topics: Aged; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Muscle Relaxation; Respiratory Ins

1992
Metastatic basal cell carcinoma: report of a case presenting with respiratory failure.
    The American journal of the medical sciences, 1991, Volume: 301, Issue:6

    Topics: Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Neopla

1991