Page last updated: 2024-10-27

fluorouracil and Reperfusion Injury

fluorouracil has been researched along with Reperfusion Injury in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, Y1
Mao, WW1
Zhang, CG1
Wan, L1
Jing, CH1
Hua, XM1
Li, ST1
Cheng, J1
Manekeller, S1
Sioutis, M1
Hirner, A1
Minor, T1

Other Studies

2 other studies available for fluorouracil and Reperfusion Injury

ArticleYear
Neuroprotective effects of intravenous transplantation of bone marrow mononuclear cells from 5-fluorouracil pre-treated rats on ischemic stroke.
    Behavioural brain research, 2016, Mar-15, Volume: 301

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Brain; Brain Ischemia; Cell Survival; Disea

2016
[Influence of neoadjuvant chemotherapy on liver integrity and ischemic tolerance].
    Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Chemotherapy, Adjuvant;

2008