Page last updated: 2024-10-27

fluorouracil and Rectal Diseases

fluorouracil has been researched along with Rectal Diseases in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Rectal Diseases: Pathological developments in the RECTUM region of the large intestine (INTESTINE, LARGE).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Golden, GT1
Rosenthal, JD1
Shaw, A1
Classen, JN1
Martin, RE1
Sabagal, J1
Gear, EV1

Reviews

2 reviews available for fluorouracil and Rectal Diseases

ArticleYear
Iatrogenic lesions of the colon and rectum.
    Southern medical journal, 1975, Volume: 68, Issue:11

    Topics: Adult; Aged; Angiography; Barium Sulfate; Cathartics; Colon; Colonic Diseases; Cyclophosphamide; Ele

1975
Dobbins WO 3d,+DOBBINS WO III: Rectal biopsy. A review of its diagnostic usefulness.
    Gastroenterology, 1968, Volume: 55, Issue:4

    Topics: Amyloidosis; Biopsy; Colitis, Ulcerative; Crohn Disease; Cystic Fibrosis; Cysts; Deficiency Diseases

1968

Other Studies

1 other study available for fluorouracil and Rectal Diseases

ArticleYear
Carcinoma of the rectum in adolescence.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adolescent; Age Factors; Cyclophosphamide; Fluorouracil; Humans; Hydroneph

1975