fluorouracil has been researched along with Puberty, Precocious in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Puberty, Precocious: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, JP | 1 |
| Dockerty, MB | 1 |
| Symmonds, RE | 1 |
| Hayles, AB | 1 |
| Heinrich, UE | 1 |
| Bolkenius, M | 1 |
| Daum, R | 1 |
| Oppermann, HC | 1 |
| Mehls, O | 1 |
| Brandeis, WE | 1 |
2 other studies available for fluorouracil and Puberty, Precocious
| Article | Year |
|---|---|
Ovarian and parovarian tumors in infants and children.
Topics: Adenocarcinoma; Adolescent; Child; Child, Preschool; Dysgerminoma; Female; Fluorouracil; Histocytoch | 1967 |
Virilizing hepatoblastoma--significance of alpha-1-fetoprotein and human chorionic gonadotropin as tumor markers in diagnosis and follow-up.
Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Chorionic Gonadotropin; Cyclophosphamide; Doxorubicin | 1981 |