fluorouracil has been researched along with Prostatic Hyperplasia in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Prostatic Hyperplasia: Increase in constituent cells in the PROSTATE, leading to enlargement of the organ (hypertrophy) and adverse impact on the lower urinary tract function. This can be caused by increased rate of cell proliferation, reduced rate of cell death, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective study of 5-Fu in the treatment of prostatic hyperplasia was commenced in 1981." | 5.27 | 5-Fluorouracil (5-Fu) in the treatment of prostatic hyperplasia. ( Wei, XY; Zhou, XM, 1987) |
| "A prospective study of 5-Fu in the treatment of prostatic hyperplasia was commenced in 1981." | 1.27 | 5-Fluorouracil (5-Fu) in the treatment of prostatic hyperplasia. ( Wei, XY; Zhou, XM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kitsukawa, S | 1 |
| Kinn, T | 1 |
| Yoshida, T | 1 |
| Yonese, J | 1 |
| Izutami, T | 1 |
| Fukui, I | 1 |
| Ishikawa, Y | 1 |
| Varkarakis, MJ | 1 |
| Gaeta, JF | 1 |
| Mirand, EA | 1 |
| Murphy, GP | 1 |
| Wei, XY | 1 |
| Zhou, XM | 1 |
| Yang, OB | 1 |
| Cheng, JY | 1 |
| Basso, A | 1 |
2 reviews available for fluorouracil and Prostatic Hyperplasia
| Article | Year |
|---|---|
[Successful multidisciplinary treatment for bladder cancer with priapism. A case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Comb | 1998 |
Genitourinary-tract problems of the aged male.
Topics: Adenocarcinoma; Age Factors; Aged; Cyclophosphamide; Cyproterone; Diethylstilbestrol; Fluorouracil; | 1974 |
1 trial available for fluorouracil and Prostatic Hyperplasia
| Article | Year |
|---|---|
Preoperative use of 5-fluorouracil to reduce operative bleeding in transurethral resection of prostate.
Topics: Aged; Fluorouracil; Hemostasis, Surgical; Humans; Male; Middle Aged; Premedication; Prostatectomy; P | 1989 |
2 other studies available for fluorouracil and Prostatic Hyperplasia
| Article | Year |
|---|---|
Morphological responses of benign human prostatic hypertrophic tissue to chemotherapeutic agents in an in vitro culture system.
Topics: Aged; Altretamine; Dacarbazine; Fluorouracil; Humans; Lomustine; Male; Microscopy; Middle Aged; Orga | 1975 |
5-Fluorouracil (5-Fu) in the treatment of prostatic hyperplasia.
Topics: Adult; Aged; Aged, 80 and over; Fluorouracil; Humans; Male; Middle Aged; Prospective Studies; Prosta | 1987 |