fluorouracil has been researched along with Proctocolitis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Proctocolitis: Inflammation of the RECTUM and the distal portion of the COLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kendal, WS | 1 |
| Jonker, D | 1 |
| Stern, H | 1 |
| Moyana, T | 1 |
| Sweeney, T | 1 |
| Rieger, N | 1 |
| Mackay, J | 1 |
2 other studies available for fluorouracil and Proctocolitis
| Article | Year |
|---|---|
Acute proctocolitis with commencement of neoadjuvant chemoradiation for rectal cancer.
Topics: Acute Disease; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Dose Fractionation, Radiation; | 2006 |
Neutropenic proctosigmoiditis complicating breast cancer chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clostridium Infections; | 1999 |