fluorouracil has been researched along with Primary Peritonitis in 36 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 60-year-old man with pancreatic cancer was admitted due to massive ascites in the course of gemcitabine treatment." | 3.74 | [An autopsy case of pancreatic cancer with poor performance status due to peritonitis carcinomatosa treated successfully with continuous infusion of low-dose 5-FU with octreotide]. ( Kayahara, M; Kitagawa, S; Minato, H; Mouri, H; Ohta, T; Ohtsubo, K; Tsuchiyama, T; Watanabe, H, 2008) |
| " In our report, a middle age patient suffering from locally advanced gastric cancer with peritonitis carcinomatosa and ascites was treated with neoadjuvant chemotherapy (DCF: docetaxel, cisplatin, fluorouracil protocol) successfully, as at the restaging examination total tumor regression was found." | 3.73 | [Complete regression after neoadjuvant chemotherapy in locally advanced gastric cancer causing peritonitis carcinomatosa--a case report]. ( Ember, A; Esik, O; Horváth, OP; Kalmár, K; Papp, A; Yousuf, AF, 2006) |
| "To develop a new drug delivery system for the treatment of carcinomatous peritonitis, we constructed 5-fluorouracil poly L-microcapsules (5Fu-mc) by the organic phase separation technique and examined their drug-releasing capacities and anticancer effects." | 3.68 | A new anticancer drug delivery system for the management of carcinomatous peritonitis. ( Iwa, T; Ohhira, M; Sakatoku, M; Watanabe, Y; Yamada, T, 1991) |
| "Clinical studies were prospectively conducted to quantitate the toxic side-effects of 5-FU administered by either the intravenous (i." | 2.66 | Toxicity studies of adjuvant intravenous versus intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer. ( Barofsky, I; Gianola, FJ; Meyers, CE; Sugarbaker, PH; White, DE, 1986) |
| "Combined resection of colorectal cancer with surgery for synchronous liver metastases (LM) still remains controversial because of the possible higher morbidity rate, the necessity of an adequate abdominal approach for both resections and the impact on oncological results." | 1.39 | Laparoscopic resection of colorectal cancer facilitates simultaneous surgery of synchronous liver metastases. ( Belghiti, J; Bretagnol, F; Farges, O; Hatwell, C; Panis, Y, 2013) |
| " From March 2002, we started to treat patients with advanced gastric cancer (stage IV) with a new regimen; intermittent dosage of 5-FU (-->S-1), CDDP and paclitaxel utilizing the difference of cell cycle between normal and cancer cells (intermittent FP ." | 1.34 | [The third report from Sapporo Tsukisamu Hospital--chemotherapy for patients with advanced gastric cancer (peritoneal dissemination, peritonitis carcinomatosa)]. ( Hirata, K; Hiyama, S; Inui, N; Kimura, H; Kimura, Y; Shirasaka, T; Yamada, Y; Yamaguchi, K; Yamamitsu, S, 2007) |
| "One of the breast cancer patients introduced here suffered from recurrent carcinomatous pleurisy and the other from recurrent carcinomatous peritonitis." | 1.31 | [Improved QOL with cancer chemotherapy in two patients with breast cancer suffering form carcinomatous pleurisy and carcinomatous peritonitis]. ( Fujitomi, Y; Fujiyoshi, K; Yasue, K, 2000) |
| "Diffuse pyogenic gelatinous ascites and a large cystic mass with a grayish wall, and a hard solid lesion in part were found." | 1.31 | Disseminated peritoneal adenomucinosis associated with a panperitonitis-like onset: report of a case. ( Kuroki, Y; Otagiri, S; Tsukada, K, 2001) |
| "Endoscopic study revealed an advanced gastric cancer in the upper body of her stomach." | 1.30 | [A case of advanced gastric cancer with carcinomatosa peritonitis effectively treated by 5-FU and low-dose CDDP therapy]. ( Kunii, Y; Saito, E; Sakakibara, N; Tsuchiya, S; Wada, G; Yamasaki, T, 1997) |
| "A new dosage formulation (5-FU-MS), composed of 5-fluorouracil (5-FU) incorporated in polyglactin microspheres, was studied by animal experiments, which revealed the following results." | 1.29 | [Development of 5-fluorouracil incorporated in microspheres for peritoneal carcinomatosis--animal experiments]. ( Fujita, T; Hagiwara, A; Imanishi, T; Ohgaki, M; Ohyama, T; Shimotsuma, M; Shirasu, M; Takahashi, T; Tsujimoto, H; Yamazaki, J, 1995) |
| " Pharmaceutical dosage was set at approximately 30% of the increased life span (ILS) for Meth-A." | 1.28 | [Experimental study of the treatment of carcinomatous peritonitis in gastric cancer]. ( Arai, K; Kitamura, M; Miyashita, K, 1992) |
| "The cases were comprised of 9 gastric cancers, 6 colorectal cancers, 1 appendiceal carcinoma, and 1 malignant tumor of retroperitoneum, all of which were observed to have peritoneal dissemination during surgical operations." | 1.28 | [Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa]. ( Katsuki, Y; Nishimura, A; Tsuji, Y; Yasuda, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 10 (27.78) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 5 (13.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katayama, K | 1 |
| Nishino, T | 1 |
| Takahashi, Y | 1 |
| Tanaka, T | 1 |
| Okitsu, H | 1 |
| Okitsu, N | 1 |
| Hiraki, S | 1 |
| Kuwahara, T | 1 |
| Kaneko, T | 1 |
| Harada, T | 1 |
| Kawaoka, T | 1 |
| Fukuda, S | 1 |
| Mouri, H | 1 |
| Tsuchiyama, T | 1 |
| Ohtsubo, K | 1 |
| Kayahara, M | 1 |
| Ohta, T | 1 |
| Kitagawa, S | 1 |
| Minato, H | 1 |
| Watanabe, H | 1 |
| Vemula, S | 1 |
| Ramdas, B | 1 |
| Hanneman, P | 1 |
| Martin, J | 1 |
| Beggs, HE | 1 |
| Kapur, R | 1 |
| Hatwell, C | 1 |
| Bretagnol, F | 1 |
| Farges, O | 1 |
| Belghiti, J | 1 |
| Panis, Y | 1 |
| Ozturk, MA | 1 |
| Ozveren, O | 1 |
| Cinar, V | 1 |
| Erdik, B | 1 |
| Oyan, B | 1 |
| Akamo, Y | 1 |
| Takeyama, H | 1 |
| Funahashi, H | 1 |
| Yamamori, Y | 1 |
| Yamamoto, M | 1 |
| Teranishi, F | 1 |
| Manabe, T | 1 |
| Fujiwara, H | 1 |
| Terashima, M | 1 |
| Takagane, A | 1 |
| Abe, K | 1 |
| Irinoda, T | 1 |
| Yonezawa, H | 1 |
| Nakaya, T | 1 |
| Oyama, K | 1 |
| Takahashi, M | 1 |
| Saito, K | 1 |
| Aihara, H | 1 |
| Maruoka, H | 1 |
| Kiyozaki, H | 1 |
| Konishi, F | 1 |
| Inagaki, H | 1 |
| Kojima, H | 1 |
| Kato, J | 1 |
| Kojima, T | 2 |
| Fujimitsu, Y | 1 |
| Matsui, T | 1 |
| Miyashita, Y | 1 |
| Sakamoto, J | 1 |
| Bojesen, AM | 1 |
| Nielsen, OL | 1 |
| Christensen, JP | 1 |
| Bisgaard, M | 1 |
| Mimae, T | 1 |
| Ninomiya, M | 1 |
| Sasaki, H | 1 |
| Kubo, Y | 1 |
| Umeoka, T | 1 |
| Takakura, N | 1 |
| Ember, A | 1 |
| Yousuf, AF | 1 |
| Kalmár, K | 1 |
| Papp, A | 1 |
| Esik, O | 1 |
| Horváth, OP | 1 |
| Yamamitsu, S | 1 |
| Kimura, H | 1 |
| Yamada, Y | 2 |
| Inui, N | 1 |
| Hiyama, S | 1 |
| Hirata, K | 1 |
| Kimura, Y | 1 |
| Yamaguchi, K | 1 |
| Shirasaka, T | 1 |
| Kurokawa, T | 1 |
| Iwasa, H | 1 |
| Mimura, K | 1 |
| Terashima, H | 1 |
| Hiraide, H | 1 |
| Mizoguchi, O | 1 |
| Kanabe, S | 1 |
| Tamaki, K | 1 |
| Kadota, T | 1 |
| Hatsuse, K | 1 |
| Nesterenko, IuA | 1 |
| Atanov, IuP | 1 |
| Khmel'nitskiĭ, GA | 1 |
| Hagiwara, A | 1 |
| Takahashi, T | 3 |
| Shimotsuma, M | 1 |
| Shirasu, M | 1 |
| Tsujimoto, H | 1 |
| Ohyama, T | 1 |
| Ohgaki, M | 1 |
| Imanishi, T | 1 |
| Yamazaki, J | 1 |
| Fujita, T | 1 |
| Kosaka, T | 1 |
| Takano, Y | 1 |
| Nakano, Y | 1 |
| Akiyama, T | 1 |
| Kiriyama, M | 1 |
| Tomita, F | 1 |
| Saito, H | 1 |
| Kita, I | 1 |
| Takashima, S | 1 |
| Nakagawa, T | 1 |
| Okabe, T | 1 |
| Kumagai, N | 1 |
| Serizawa, H | 1 |
| Iwabuchi, N | 1 |
| Watanabe, N | 1 |
| Hamada, Y | 1 |
| Tsuchimoto, K | 1 |
| Morinaga, S | 1 |
| Ishii, H | 1 |
| Saito, E | 1 |
| Kunii, Y | 1 |
| Wada, G | 1 |
| Tsuchiya, S | 1 |
| Yamasaki, T | 1 |
| Sakakibara, N | 1 |
| Iwamoto, S | 1 |
| Kimoto, M | 1 |
| Mure, T | 1 |
| Imai, H | 1 |
| Fujimori, Y | 1 |
| Onuma, E | 1 |
| Iki, K | 1 |
| Yoshida, K | 1 |
| Tadaoka, Y | 1 |
| Kubozoe, T | 1 |
| Takeo, T | 1 |
| Murakami, T | 1 |
| Kawasaki, S | 1 |
| Yamamoto, Y | 1 |
| Tsunoda, T | 1 |
| Hirao, T | 1 |
| Imamoto, H | 1 |
| Yamazaki, K | 1 |
| Kan, K | 1 |
| Takatsuka, Y | 1 |
| Fujitomi, Y | 1 |
| Fujiyoshi, K | 1 |
| Yasue, K | 1 |
| Palermo, JA | 1 |
| Richards, F | 1 |
| Lohman, KK | 1 |
| Lovelace, JV | 1 |
| Atkinson, J | 1 |
| Case, LD | 1 |
| White, DR | 1 |
| Blackstock, AW | 1 |
| Kuroki, Y | 1 |
| Otagiri, S | 1 |
| Tsukada, K | 1 |
| Kitamura, M | 1 |
| Arai, K | 1 |
| Miyashita, K | 1 |
| Ueshima, Y | 1 |
| Taniguchi, H | 1 |
| Miyata, K | 1 |
| Suganuma, Y | 1 |
| Takeuchi, K | 1 |
| Oguro, A | 1 |
| Tsukuda, N | 1 |
| Yamada, T | 1 |
| Sakatoku, M | 1 |
| Ohhira, M | 1 |
| Watanabe, Y | 1 |
| Iwa, T | 1 |
| Tsuji, Y | 1 |
| Nishimura, A | 1 |
| Katsuki, Y | 1 |
| Yasuda, T | 1 |
| Seki, H | 1 |
| Takahashi, H | 1 |
| Kimura, K | 1 |
| Arbuck, SG | 1 |
| Trave, F | 1 |
| Douglass, HO | 1 |
| Nava, H | 1 |
| Zakrzewski, S | 1 |
| Rustum, YM | 1 |
| Gianola, FJ | 1 |
| Sugarbaker, PH | 1 |
| Barofsky, I | 1 |
| White, DE | 1 |
| Meyers, CE | 1 |
| Braly, P | 1 |
| Doroshow, J | 1 |
| Hoff, S | 1 |
| Yoshikawa, K | 1 |
| Kitaoka, H | 1 |
| Matsui, K | 1 |
| Goldman, LI | 1 |
| Lowe, S | 1 |
| al-Saleem, T | 1 |
2 reviews available for fluorouracil and Primary Peritonitis
| Article | Year |
|---|---|
Takotsubo syndrome: an underdiagnosed complication of 5-fluorouracil mimicking acute myocardial infarction.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth | 2013 |
Emulsion and activated carbon in cancer chemotherapy.
Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as | 1986 |
4 trials available for fluorouracil and Primary Peritonitis
| Article | Year |
|---|---|
In vivo studies of Gallibacterium anatis infection in chickens.
Topics: Animals; Chickens; Fluorouracil; Immunocompromised Host; Immunosuppressive Agents; Liver; Liver Dise | 2004 |
Phase II trial of adjuvant radiation and intraperitoneal 5-fluorouracil for locally advanced colon cancer: results with 10-year follow-up.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Colonic Neoplasms; Disease-Free Survival; Female; Fluo | 2000 |
Emulsion and activated carbon in cancer chemotherapy.
Topics: Administration, Oral; Adult; Aged; Animals; Bleomycin; Breast Neoplasms; Carbon; Clinical Trials as | 1986 |
Toxicity studies of adjuvant intravenous versus intraperitoneal 5-FU in patients with advanced primary colon or rectal cancer.
Topics: Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Fluorouracil; Humans | 1986 |
31 other studies available for fluorouracil and Primary Peritonitis
| Article | Year |
|---|---|
[Approximately four years of survival benefits for a case of gastric cancer postoperative carcinomatous peritonitis by combined modality therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisplatin; Combined Modality Therapy; | 2013 |
[A case of locally advanced rectal cancer successfully resected after preoperative chemotherapy].
Topics: Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined | 2013 |
[An autopsy case of pancreatic cancer with poor performance status due to peritonitis carcinomatosa treated successfully with continuous infusion of low-dose 5-FU with octreotide].
Topics: Antimetabolites, Antineoplastic; Ascites; Autopsy; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; | 2008 |
Essential role for focal adhesion kinase in regulating stress hematopoiesis.
Topics: Actins; Acute Disease; Animals; Bone Marrow Cells; Cell Movement; Cell Proliferation; Cell Survival; | 2010 |
Laparoscopic resection of colorectal cancer facilitates simultaneous surgery of synchronous liver metastases.
Topics: Adult; Aged; Anastomotic Leak; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Ad | 2013 |
[Efficacy of intraperitoneal chemotherapy for advanced Borrmann type IV gastric carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Infus | 2002 |
[Combination chemotherapy with intra-perioneal infusion of CDDP and continuous intravenous infusion of 5-FU for peritoneal metastasis in gastric cancer--analysis of long-term survivors].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cisplatin; Drug Therapy, Combin | 2002 |
Sclerosing encapsulating peritonitis (SEP) as a delayed complication of continuous hyperthermic peritoneal perfusion (CHPP): report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Cisplatin; | 2003 |
[Effective use of combination chemotherapy with paclitaxel and 5-fluorouracil in a case of non-resectable advanced gastric cancer].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Fluorouracil; Hu | 2003 |
[A case of recurrent gastric cancer with improvement of obstructive symptoms caused by carcinomatous peritonitis and prolonged survival by chemotherapy with combined use of Paclitaxel and 5-FU].
Topics: Adenocarcinoma, Scirrhous; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality | 2006 |
[Complete regression after neoadjuvant chemotherapy in locally advanced gastric cancer causing peritonitis carcinomatosa--a case report].
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Carcinoma; Chemotherapy, Adjuvant; Cisplati | 2006 |
[The third report from Sapporo Tsukisamu Hospital--chemotherapy for patients with advanced gastric cancer (peritoneal dissemination, peritonitis carcinomatosa)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Administration Schedule; Femal | 2007 |
[Intraperitoneal administration of FT-207 for mouse peritonitis carcinomatosa].
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Fluorouracil; Injections, Intraperitoneal; Macroph | 1984 |
[Results of the treatment of pancreonecrosis].
Topics: Acute Disease; Fluorouracil; Humans; Hypothermia, Induced; Infusions, Intra-Arterial; Necrosis; Panc | 1983 |
[Development of 5-fluorouracil incorporated in microspheres for peritoneal carcinomatosis--animal experiments].
Topics: Animals; Ascitic Fluid; Delayed-Action Preparations; Fluorouracil; Male; Mice; Microspheres; Neoplas | 1995 |
[Intraarterial infusion chemotherapy for recurrent or unresectable gastric cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Etoposide; Female; Fluoroura | 1993 |
[A case of carcinomatous peritonitis for which combination therapy of 5-FU, leucovorin and cisplatin was effective].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Cisplatin; Fl | 1996 |
[A case of advanced gastric cancer with carcinomatosa peritonitis effectively treated by 5-FU and low-dose CDDP therapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Drug Administration | 1997 |
[A case of papillary adenocarcinoma of the stomach with liver metastases and carcinomatous peritonitis treated effectively by methotrexate/5-fluorouracil sequential chemotherapy].
Topics: Adenocarcinoma, Papillary; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; D | 1997 |
[Effects of intravenous infusion of 5-FU and intraperitoneal injection of low-dose CDDP on 3 cases with ascites owing to peritonitis carcinomatosa of postoperative gastric carcinoma and debility].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Drug Administration | 1998 |
[Improved QOL with cancer chemotherapy in two patients with breast cancer suffering form carcinomatous pleurisy and carcinomatous peritonitis].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubic | 2000 |
Disseminated peritoneal adenomucinosis associated with a panperitonitis-like onset: report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Cisplatin; Combined Modality Therapy; Diagn | 2001 |
[Experimental study of the treatment of carcinomatous peritonitis in gastric cancer].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Infusions, Parente | 1992 |
[Superior mesenteric arterial infusion chemotherapy in patient with both peritoneal carcinomatosis and liver metastasis].
Topics: Animals; Fluorouracil; Infusions, Intra-Arterial; Intestine, Small; Liver; Liver Neoplasms; Mesenter | 1992 |
A new anticancer drug delivery system for the management of carcinomatous peritonitis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Drug Carriers; Erythrocyte Count; Fluoro | 1991 |
[Evaluation of intraperitoneal cancer chemotherapy using an implantable reservoir in patients with peritonitis carcinomatosa].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Cisplatin; Colorectal Ne | 1990 |
[Concentration of 5-FU and tegafur in the ascites fluid in patients with peritonitis carcinomatosa after UFT oral administration].
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Ascitic Fluid; Fluorouracil; G | 1987 |
Phase I and pharmacologic studies of intraperitoneal leucovorin and 5-fluorouracil in patients with advanced cancer.
Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Drug Ev | 1986 |
Technical aspects of intraperitoneal chemotherapy in abdominal carcinomatosis.
Topics: Abdominal Neoplasms; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherap | 1986 |
[Continuous intra-arterial infusion of antineoplastic agents in cancerous peritonitis, with special reference to cancer].
Topics: Adult; Aged; Cytarabine; Female; Femoral Artery; Fluorouracil; Humans; Injections, Intra-Arterial; M | 1971 |
Effect of fluorouracil on intestinal anastomoses in the rat.
Topics: Animals; Collagen; Fluorouracil; Intestine, Small; Male; Peritonitis; Postoperative Complications; R | 1969 |