fluorouracil has been researched along with Precursor T-Cell Lymphoblastic Leukemia-Lymphoma in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma: A leukemia/lymphoma found predominately in children and young adults and characterized LYMPHADENOPATHY and THYMUS GLAND involvement. It most frequently presents as a lymphoma, but a leukemic progression in the bone marrow is common.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiang, MY | 1 |
| Shestova, O | 1 |
| Xu, L | 1 |
| Aster, JC | 1 |
| Pear, WS | 1 |
1 other study available for fluorouracil and Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells.
Topics: 3T3 Cells; Animals; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Flow Cytometry; Fluorour | 2013 |