fluorouracil has been researched along with Poultry Diseases in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Poultry Diseases: Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The reduction in PMN was dose-dependent with a dosage of 200 mg/kg body weight of 5-FU, causing suppression of PMN to almost undetectable levels." | 1.29 | The effect of 5-fluorouracil treatment of chicks: a cell depletion model for the study of avian polymorphonuclear leukocytes and natural host defenses. ( Corrier, DE; DeLoach, JR; Hargis, BM; Kogut, MH; Tellez, G, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, J | 1 |
| Shen, H | 1 |
| Wang, Z | 1 |
| Huang, S | 1 |
| Li, Q | 1 |
| Zhou, Q | 1 |
| Qin, J | 1 |
| Xie, Q | 1 |
| Chen, F | 1 |
| Bojesen, AM | 2 |
| Nielsen, OL | 2 |
| Christensen, JP | 2 |
| Bisgaard, M | 3 |
| Petersen, KD | 1 |
| Kabell, S | 1 |
| Igyártó, BZ | 1 |
| Magyar, A | 1 |
| Hajdú, Z | 1 |
| Biró, E | 1 |
| Oláh, I | 1 |
| Kogut, MH | 2 |
| Tellez, GI | 1 |
| McGruder, ED | 1 |
| Hargis, BM | 2 |
| Williams, JD | 1 |
| Corrier, DE | 2 |
| DeLoach, JR | 2 |
| Tellez, G | 1 |
| Johnson, JR | 1 |
| Hansen, MF | 1 |
| Nassar, RF | 1 |
1 trial available for fluorouracil and Poultry Diseases
| Article | Year |
|---|---|
In vivo studies of Gallibacterium anatis infection in chickens.
Topics: Animals; Chickens; Fluorouracil; Immunocompromised Host; Immunosuppressive Agents; Liver; Liver Dise | 2004 |
6 other studies available for fluorouracil and Poultry Diseases
| Article | Year |
|---|---|
Attenuation of duck Tembusu virus ZJSBL01 strain following serial passage in BHK-21 cells supplied with 5-Fluorouracil.
Topics: Animals; Antibodies, Viral; Ducks; Flavivirus; Fluorouracil; Immunization; Kinetics; Mutation; Poult | 2019 |
Pasteurella multocida infection in heterophil-depleted chickens.
Topics: Animals; Chickens; Fluorouracil; Giant Cells; Granulocytes; Lung; Pasteurella Infections; Pasteurell | 2004 |
Impact of heterophil granulocyte depletion caused by 5-fluorouracil on infectious bursal disease virus infection in specific pathogen free chickens.
Topics: Animals; Birnaviridae Infections; Chickens; Fluorouracil; Granulocytes; Infectious bursal disease vi | 2006 |
Heterophils are decisive components in the early responses of chickens to Salmonella enteritidis infections.
Topics: Animals; Chickens; Female; Fluorouracil; Granulocytes; Leukocyte Count; Liver; Male; Poultry Disease | 1994 |
The effect of 5-fluorouracil treatment of chicks: a cell depletion model for the study of avian polymorphonuclear leukocytes and natural host defenses.
Topics: Agranulocytosis; Animals; Chickens; Dose-Response Relationship, Drug; Fluorouracil; Lymphocyte Deple | 1993 |
Ascaridia galli: effects of immunosuppressive drugs or bursectomy in chickens.
Topics: Animals; Ascariasis; Ascaridia; Azauridine; Bursa of Fabricius; Chickens; Chlorambucil; Cortisone; D | 1974 |