fluorouracil has been researched along with Porphyria in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keczkes, K | 1 |
| Barker, DJ | 1 |
| Kappas, A | 1 |
| Granick, S | 1 |
| Thompson, RP | 1 |
| Nicholson, DC | 1 |
| Farnan, T | 1 |
| Whitmore, DN | 1 |
| Williams, R | 1 |
| Markoff, N | 1 |
1 review available for fluorouracil and Porphyria
| Article | Year |
|---|---|
[Long-term therapy of liver diseases].
Topics: Aged; Anabolic Agents; Chronic Disease; Cortisone; Diet Therapy; Fatty Liver; Female; Fluorouracil; | 1972 |
3 other studies available for fluorouracil and Porphyria
| Article | Year |
|---|---|
Malignant hepatoma associated with acquired hepatic cutaneous porphyria.
Topics: Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Feces; Female; Fluorouracil; Hu | 1976 |
Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process.
Topics: Acetates; Amides; Animals; Azaserine; Azo Compounds; Chick Embryo; Culture Techniques; Cycloheximide | 1968 |
Cutaneous porphyria due to a malignant primary hepatoma.
Topics: Aged; Carcinoma, Hepatocellular; Feces; Female; Fluorouracil; Humans; Liver Neoplasms; Photosensitiv | 1970 |