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fluorouracil and Porphyria Cutanea Tarda

fluorouracil has been researched along with Porphyria Cutanea Tarda in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Porphyria Cutanea Tarda: An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laidman, PJ1
Gebauer, K1
Trotter, J1

Other Studies

1 other study available for fluorouracil and Porphyria Cutanea Tarda

ArticleYear
5-Fluorouracil-induced pseudoporphyria.
    Australian and New Zealand journal of medicine, 1992, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Diagnosis, Differential; Fluorouracil; Humans; Leucovorin; Lung Neoplasms; Male; Mid

1992