fluorouracil has been researched along with Polycythemia Vera in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, J | 1 |
| Axilbund, J | 1 |
| Dalton, WB | 1 |
| Laheru, D | 1 |
| Watkins, S | 1 |
| Chu, D | 1 |
| Cravero, K | 1 |
| Button, B | 1 |
| Kyker-Snowman, K | 1 |
| Waters, I | 1 |
| Gocke, CD | 1 |
| Lauring, J | 1 |
| Park, BH | 1 |
1 other study available for fluorouracil and Polycythemia Vera
| Article | Year |
|---|---|
A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation.
Topics: Abdominal Pain; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; C | 2016 |