fluorouracil has been researched along with Polycystic Kidney Diseases in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Polycystic Kidney Diseases: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cíftçíoglu, N | 1 |
| Miller-Hjelle, MA | 1 |
| Hjelle, JT | 1 |
| Kajander, EO | 1 |
| Franksson, C | 1 |
| Bergstrand, A | 1 |
| Ljungdahl, I | 1 |
| Magnusson, G | 1 |
| Nordenstam, H | 1 |
2 other studies available for fluorouracil and Polycystic Kidney Diseases
| Article | Year |
|---|---|
Inhibition of nanobacteria by antimicrobial drugs as measured by a modified microdilution method.
Topics: Anti-Bacterial Agents; Bacteria; Diphosphonates; Fluorouracil; Kidney Calculi; Microbial Sensitivity | 2002 |
Renal carcinoma (hypernephroma) occurring in 5 siblings.
Topics: Adenocarcinoma; Adult; Biopsy; Female; Fluorouracil; Humans; Kidney; Kidney Neoplasms; Male; Middle | 1972 |