Page last updated: 2024-10-27

fluorouracil and Pneumonia, Viral

fluorouracil has been researched along with Pneumonia, Viral in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Pneumonia, Viral: Inflammation of the lung parenchyma that is caused by a viral infection.

Research Excerpts

ExcerptRelevanceReference
" The author here is proposing to test 5-FU in combination with a number of deoxynucleosides on animal models infected with this Covid-19."1.565-Fluorouracil in combination with deoxyribonucleosides and deoxyribose as possible therapeutic options for the Coronavirus, COVID-19 infection. ( Ahmad, SI, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Jin, Z1
Zhao, Y1
Sun, Y1
Zhang, B1
Wang, H1
Wu, Y1
Zhu, Y1
Zhu, C1
Hu, T1
Du, X1
Duan, Y1
Yu, J1
Yang, X2
Yang, K1
Liu, X1
Guddat, LW1
Xiao, G1
Zhang, L1
Yang, H1
Rao, Z1
Ahmad, SI1
Vidra, R1
Bodea, R1
Mercea, V1
Nemes, A1
García-Montesinos-De la Peña, M1
Oteiza-López, L1
Aldunate-Calvo, S1
Gómez-Sánchez, MJ1
Sáenz-Bañuelos, JJ1
Tihista-Jiménez, JA1

Other Studies

4 other studies available for fluorouracil and Pneumonia, Viral

ArticleYear
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur.
    Nature structural & molecular biology, 2020, Volume: 27, Issue:6

    Topics: Animals; Betacoronavirus; Chlorocebus aethiops; Coronavirus 3C Proteases; Coronavirus Infections; CO

2020
5-Fluorouracil in combination with deoxyribonucleosides and deoxyribose as possible therapeutic options for the Coronavirus, COVID-19 infection.
    Medical hypotheses, 2020, Volume: 142

    Topics: Adenosine Monophosphate; Alanine; Betacoronavirus; Chloroquine; Clinical Trials as Topic; Coronaviru

2020
Challenges of pancreatic cancer chemotherapy in the COVID-19 era.
    Journal of gastrointestinal and liver diseases : JGLD, 2020, 06-04, Volume: 29, Issue:2

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Betacoronavirus; Capeci

2020
[Herpes simplex virus bronchopneumonitis in patient with acute respiratory failure after surgery].
    Medicina intensiva, 2010, Volume: 34, Issue:2

    Topics: Acute Disease; Acyclovir; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antiviral Agents; B

2010