Page last updated: 2024-10-27

fluorouracil and Periphlebitis

fluorouracil has been researched along with Periphlebitis in 7 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Periphlebitis: Periphlebitis is inflammation of the outer coat of a vein or of tissues surrounding the vein.

Research Excerpts

ExcerptRelevanceReference
"To establish whether using alternating arms for peripheral intravenous epirubicin administration affects the severity or duration of epirubicin-induced phlebitis."7.91Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis. ( Borley, A; Dolan, G; Hanna, L; Roberts, R; Williams, EM, 2019)
"To establish whether using alternating arms for peripheral intravenous epirubicin administration affects the severity or duration of epirubicin-induced phlebitis."3.91Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis. ( Borley, A; Dolan, G; Hanna, L; Roberts, R; Williams, EM, 2019)
"Leukopenia was more frequent in the simultaneous than in the sequential arm (p = 0."2.67A randomized phase II study comparing sequential versus simultaneous chemo-radiotherapy in patients with unresectable locally advanced squamous cell cancer of the head and neck. ( Carlini, P; Cercato, MC; Cognetti, F; Del Vecchio, MR; Giannarelli, D; Impiombato, FA; Marzetti, F; Milella, M; PinnarĂ², P, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roberts, R1
Hanna, L1
Borley, A1
Dolan, G1
Williams, EM1
Kimura, T1
Iwase, K1
Aono, T1
Nakai, S1
Fujii, M1
Nishikawa, K1
Matsuda, C1
Shimada, K1
Hirota, M1
Nasu, S1
Wada, D1
Hasegawa, J1
Tanaka, Y1
Legha, SS1
Ajani, JA1
Blumenschein, GR1
Hortobagyi, GN1
Buzdar, AU1
PinnarĂ², P1
Cercato, MC1
Giannarelli, D1
Carlini, P1
Del Vecchio, MR1
Impiombato, FA1
Marzetti, F1
Milella, M1
Cognetti, F1
Berdonces Fornieles, M1
Grady, ED1
Nolan, TR1
Crumbley, AJ1
Grady, CK1
Hill, GJ1
Grage, TB1
Wilson, W1
Ansfield, FJ1

Trials

1 trial available for fluorouracil and Periphlebitis

ArticleYear
A randomized phase II study comparing sequential versus simultaneous chemo-radiotherapy in patients with unresectable locally advanced squamous cell cancer of the head and neck.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:6

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi

1994

Other Studies

6 other studies available for fluorouracil and Periphlebitis

ArticleYear
Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis.
    European journal of cancer care, 2019, Volume: 28, Issue:5

    Topics: Administration, Intravenous; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemo

2019
[Feasibility of peripheral vein during FOLFOX/FOLFIRI chemotherapy through peripheral venous system].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Feasibility Studies; Fema

2008
Combination chemotherapy of metastatic breast carcinoma with cyclophosphamide, adriamycin, and peptichemio.
    Cancer, 1984, May-01, Volume: 53, Issue:9

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms;

1984
[The complications associated with the administration of 5-fluorouracil].
    Revista de enfermeria (Barcelona, Spain), 1991, Volume: 14, Issue:160

    Topics: Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Phlebitis; Time Factors

1991
Chemotherapy and radiation therapy together to treat cancer.
    Oncology, 1970, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Heparin

1970
5-fluorouracil intravenous infusion for 48 hours, repeated every two weeks.
    Journal of surgical oncology, 1972, Volume: 4, Issue:1

    Topics: Adult; Aged; Breast Neoplasms; Diarrhea; Evaluation Studies as Topic; Female; Fluorouracil; Gastroin

1972