fluorouracil has been researched along with Periphlebitis in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Periphlebitis: Periphlebitis is inflammation of the outer coat of a vein or of tissues surrounding the vein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To establish whether using alternating arms for peripheral intravenous epirubicin administration affects the severity or duration of epirubicin-induced phlebitis." | 7.91 | Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis. ( Borley, A; Dolan, G; Hanna, L; Roberts, R; Williams, EM, 2019) |
| "To establish whether using alternating arms for peripheral intravenous epirubicin administration affects the severity or duration of epirubicin-induced phlebitis." | 3.91 | Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis. ( Borley, A; Dolan, G; Hanna, L; Roberts, R; Williams, EM, 2019) |
| "Leukopenia was more frequent in the simultaneous than in the sequential arm (p = 0." | 2.67 | A randomized phase II study comparing sequential versus simultaneous chemo-radiotherapy in patients with unresectable locally advanced squamous cell cancer of the head and neck. ( Carlini, P; Cercato, MC; Cognetti, F; Del Vecchio, MR; Giannarelli, D; Impiombato, FA; Marzetti, F; Milella, M; Pinnarò, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roberts, R | 1 |
| Hanna, L | 1 |
| Borley, A | 1 |
| Dolan, G | 1 |
| Williams, EM | 1 |
| Kimura, T | 1 |
| Iwase, K | 1 |
| Aono, T | 1 |
| Nakai, S | 1 |
| Fujii, M | 1 |
| Nishikawa, K | 1 |
| Matsuda, C | 1 |
| Shimada, K | 1 |
| Hirota, M | 1 |
| Nasu, S | 1 |
| Wada, D | 1 |
| Hasegawa, J | 1 |
| Tanaka, Y | 1 |
| Legha, SS | 1 |
| Ajani, JA | 1 |
| Blumenschein, GR | 1 |
| Hortobagyi, GN | 1 |
| Buzdar, AU | 1 |
| Pinnarò, P | 1 |
| Cercato, MC | 1 |
| Giannarelli, D | 1 |
| Carlini, P | 1 |
| Del Vecchio, MR | 1 |
| Impiombato, FA | 1 |
| Marzetti, F | 1 |
| Milella, M | 1 |
| Cognetti, F | 1 |
| Berdonces Fornieles, M | 1 |
| Grady, ED | 1 |
| Nolan, TR | 1 |
| Crumbley, AJ | 1 |
| Grady, CK | 1 |
| Hill, GJ | 1 |
| Grage, TB | 1 |
| Wilson, W | 1 |
| Ansfield, FJ | 1 |
1 trial available for fluorouracil and Periphlebitis
| Article | Year |
|---|---|
A randomized phase II study comparing sequential versus simultaneous chemo-radiotherapy in patients with unresectable locally advanced squamous cell cancer of the head and neck.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi | 1994 |
6 other studies available for fluorouracil and Periphlebitis
| Article | Year |
|---|---|
Epirubicin chemotherapy in women with breast cancer: Alternating arms for intravenous administration to reduce chemical phlebitis.
Topics: Administration, Intravenous; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemo | 2019 |
[Feasibility of peripheral vein during FOLFOX/FOLFIRI chemotherapy through peripheral venous system].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Feasibility Studies; Fema | 2008 |
Combination chemotherapy of metastatic breast carcinoma with cyclophosphamide, adriamycin, and peptichemio.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Neoplasms; | 1984 |
[The complications associated with the administration of 5-fluorouracil].
Topics: Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Phlebitis; Time Factors | 1991 |
Chemotherapy and radiation therapy together to treat cancer.
Topics: Antineoplastic Agents; Cell Division; Cyclophosphamide; DNA, Neoplasm; Female; Fluorouracil; Heparin | 1970 |
5-fluorouracil intravenous infusion for 48 hours, repeated every two weeks.
Topics: Adult; Aged; Breast Neoplasms; Diarrhea; Evaluation Studies as Topic; Female; Fluorouracil; Gastroin | 1972 |