Page last updated: 2024-10-27

fluorouracil and Penile Neoplasms

fluorouracil has been researched along with Penile Neoplasms in 65 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Penile Neoplasms: Cancers or tumors of the PENIS or of its component tissues.

Research Excerpts

ExcerptRelevanceReference
"An 18-month-old cross-bred Fjord pony colt presenting a fibrosarcoma of the prepuce with severe infiltrative growth, was treated by topical application of 5-fluorouracil."7.70Successful treatment of an equine preputial fibrosarcoma using 5-fluorouracil/evaluation of the treatment using quantitative PCNA and Ki67 (MIB 1) immunostaining. (case report). ( De Kruif, A; Ducatelle, R; Roels, S; van De Vijver, B, 1998)
"5-Fluorouracil (5-FU) cream was compared with podophyllin 25 percent in alcohol for treating genital and urethral condylomata acuminata."7.655-Fluorouracil in the treatment of penile and urethral condylomata acuminata. ( Wallin, J, 1977)
"Seven adult men with biopsy-confirmed erythroplasia of Queyrat (EQ) were cured of their disease with topically applied 5-fluorouracil (5-FU) under occlusion."7.65Erythroplasia of Queyrat: treatment with topical 5-fluorouracil. ( Carson, TE; Goette, DK, 1976)
"Three patients with biopsy-confirmed erythroplasia of Queyrat were treated with topically applied fluorouracil."7.65Erythroplasia of Queyrat. Treatment with topically applied fluorouracil. ( DeVillez, RL; Elgart, M; Goette, DK, 1975)
"An 18-month-old cross-bred Fjord pony colt presenting a fibrosarcoma of the prepuce with severe infiltrative growth, was treated by topical application of 5-fluorouracil."3.70Successful treatment of an equine preputial fibrosarcoma using 5-fluorouracil/evaluation of the treatment using quantitative PCNA and Ki67 (MIB 1) immunostaining. (case report). ( De Kruif, A; Ducatelle, R; Roels, S; van De Vijver, B, 1998)
"5-Fluorouracil (5-FU) cream was compared with podophyllin 25 percent in alcohol for treating genital and urethral condylomata acuminata."3.655-Fluorouracil in the treatment of penile and urethral condylomata acuminata. ( Wallin, J, 1977)
"Seven adult men with biopsy-confirmed erythroplasia of Queyrat (EQ) were cured of their disease with topically applied 5-fluorouracil (5-FU) under occlusion."3.65Erythroplasia of Queyrat: treatment with topical 5-fluorouracil. ( Carson, TE; Goette, DK, 1976)
"Three patients with biopsy-confirmed erythroplasia of Queyrat were treated with topically applied fluorouracil."3.65Erythroplasia of Queyrat. Treatment with topically applied fluorouracil. ( DeVillez, RL; Elgart, M; Goette, DK, 1975)
"Penis cancer is rare and clinical trial evidence on which to base treatment decisions is limited."2.78Phase II trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic penis cancer (CRUK/09/001). ( Bahl, A; Barber, J; Burnett, S; Carrington, B; Chester, JD; Cruickshank, C; Elliott, T; Hall, E; Harland, SJ; Nicholson, S; Pickering, L; Thomson, A; Waters, R, 2013)
"Concerning penis cancer, the optimal protocols validated by a high level of evidence are missing."2.49[Chemotherapy in male external genital organs (testicular and penile cancer)]. ( Bastide, C; Bruyère, F; Deville, JL; Flechon, A; Guy, L; Karsenty, G, 2013)
"Data on PeIN from the Swedish National Penile Cancer Register were analysed regarding treatment in relation to age, size of the PeIN lesion, localization of the PeIN lesion and complications using chi-squared tests and logistic regression."1.72Incidence of penile intraepithelial neoplasia and treatment strategies in Sweden 2000-2019. ( Bjartling, C; Forslund, O; Kristiansen, S; Svensson, Å; Torbrand, C, 2022)
" Fifty percent of patients reported Common Terminology Criteria for Adverse Events v5."1.62Topical chemotherapy for penile carcinoma in situ: Contemporary outcomes and reported toxicity. ( Aydin, AM; Chahoud, J; Cheryian, SK; Hajiran, A; Pow-Sang, JM; Spiess, PE; Zemp, L, 2021)
"Penile squamous cell carcinoma (pSCC) is a relatively rare disease in Western world but is a significant health problem in developing countries like India."1.46Successful downstaging of locally recurrent penile squamous cell carcinoma with neoadjuvant nanosomal docetaxel lipid suspension (NDLS) based regimen followed by curative surgery. ( Bunger, D; Gupta, S; Pawar, SS, 2017)
"To review outcomes of the treatment of carcinoma in situ (CIS) of the penis at a large supra-regional penile cancer network, where centralisation has permitted greater experience with treatment outcomes, and suggest treatment strategies."1.42The treatment of penile carcinoma in situ (CIS) within a UK supra-regional network. ( Jones, S; Lau, MW; Lucky, M; Murthy, KV; Parr, NJ; Rogers, B; Sangar, VK, 2015)
"Grade 2 anorexia was the most frequent chemotherapy-related toxicity and no toxic death was noted."1.40Intraarterial chemotherapy as the first-line therapy in penile cancer. ( Chen, CH; Chiang, PH; Shen, YC, 2014)
"A total of 96 patients with penile cancer were included, the expression of TS and DPD in tumor tissues were examined by immunohistochemistry method, the relationship of TS and DPD expressions with the clinical characters were also analyzed."1.39[Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in penile cancer]. ( Chen, X; Chen, Y; Cheng, K; Ding, J; Dong, H; Gou, HF; Li, LH; Liu, JY; Men, HT; Tang, J; Zhao, F, 2013)
"The use of topical agents in the treatment of carcinoma in situ (CIS) of the penis has been well described in the literature."1.38Treatment of carcinoma in situ of the glans penis with topical chemotherapy agents. ( Alnajjar, HM; Bolgeri, M; Lam, W; Perry, MJ; Rees, RW; Watkin, NA, 2012)
"Our diagnosis was penile cancer with bilateral inguinal lymph node metastasis and clinical staging T4N3M0."1.36A case of local advanced penile cancer treated with multimodality therapy. ( Arima, K; Kato, M; Soga, N; Sugimura, Y, 2010)
"To evaluate the therapeutic activity of taxanes (T) in combination with cisplatin-fluorouracil (PF) for salvage of primarily unresectable or relapsed nodal metastases from squamous cell carcinoma (SCC) of the penis."1.35Taxanes in combination with cisplatin and fluorouracil for advanced penile cancer: preliminary results. ( Milani, A; Nicolai, N; Pizzocaro, G, 2009)
"Metastatic penoscrotal extramammary Paget's disease (EMPD) has seldom been reported in the literature."1.35Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's disease. ( Dai, B; Mao, HR; Shen, YJ; Yao, XD; Ye, DW; Zhang, HL; Zhang, SL; Zhu, Y, 2009)
"Patients with penile cancer sometimes refuse surgery under the consideration of cosmetic and functional impact."1.35Intra-arterial infusion of chemotherapy in the treatment of penile cancer. ( Chen, CH; Chiang, PH; Kang, CH, 2009)
"Hypercalcemia is the most common metabolic disorder associated with malignancies."1.30Hypercalcemia and carcinoma of the penis. ( Ago, CT; Videtic, GM; Winquist, EW, 1997)
"A total of 8 patients with advanced squamous cell carcinoma of the penis (Jackson stages III and IV) received chemotherapy with 100 mg."1.28Cisplatin and 5-fluorouracil in advanced cancer of the penis. ( Fossa, SD; Ous, S; Shammas, FV, 1992)
"An ususual case of Bowen's disease of the skin of the penile shaft treated successfully with topical 5-fluorouracil is presented along with a review of different modes of treatment."1.26Bowen's disease of shaft of penis. Successful treatment with 5-fluorouracil. ( Castro, VL; Mouded, IM; Newman, HR; Tolia, BM, 1976)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199018 (27.69)18.7374
1990's14 (21.54)18.2507
2000's11 (16.92)29.6817
2010's19 (29.23)24.3611
2020's3 (4.62)2.80

Authors

AuthorsStudies
Sil, A1
Bhanja, DB1
Panigrahi, A1
Kumar Biswas, S1
Kristiansen, S1
Torbrand, C1
Svensson, Å1
Forslund, O1
Bjartling, C1
Hajiran, A1
Zemp, L1
Aydin, AM1
Cheryian, SK1
Pow-Sang, JM1
Chahoud, J1
Spiess, PE1
Gupta, S1
Pawar, SS1
Bunger, D1
Colombo, AF1
Boito, R1
Bova, F1
Greco, S1
Lucà, R1
Sellaro, A1
Rizzuto, G1
Nicholson, S1
Hall, E1
Harland, SJ1
Chester, JD1
Pickering, L1
Barber, J1
Elliott, T1
Thomson, A1
Burnett, S1
Cruickshank, C1
Carrington, B1
Waters, R1
Bahl, A1
Deville, JL1
Flechon, A1
Bruyère, F1
Karsenty, G1
Guy, L1
Bastide, C1
Morton, CA1
Birnie, AJ1
Eedy, DJ1
Zhao, F1
Tang, J1
Gou, HF1
Li, LH1
Dong, H1
Chen, Y1
Cheng, K1
Ding, J1
Chen, X1
Men, HT1
Liu, JY1
Takamoto, D1
Kasuga, J1
Yumura, Y1
Koizumi, M1
Hanai, T1
Ishida, H1
Hattori, Y1
Teranishi, J1
Miyoshi, Y1
Kondo, K1
Noguchi, K1
Luo, NQ1
Zhang, ZH1
Ma, Y1
Djajadiningrat, RS1
Bergman, AM1
van Werkhoven, E1
Vegt, E1
Horenblas, S2
Chiang, PH2
Chen, CH2
Shen, YC1
Lucky, M1
Murthy, KV1
Rogers, B1
Jones, S1
Lau, MW1
Sangar, VK1
Parr, NJ1
Zhang, S1
Zhu, Y2
Ye, D1
Nicolai, N4
Sangalli, LM1
Necchi, A3
Giannatempo, P2
Paganoni, AM1
Colecchia, M3
Piva, L3
Catanzaro, MA1
Biasoni, D2
Stagni, S2
Torelli, T3
Raggi, D2
Faré, E1
Pizzocaro, G3
Salvioni, R3
Lo Vullo, S1
Catanzaro, M2
Mariani, L1
Milani, A1
Hakenberg, OW1
Ye, DW1
Yao, XD1
Zhang, SL1
Dai, B1
Zhang, HL1
Shen, YJ1
Mao, HR1
Eliason, M1
Bowen, G1
Bowen, A1
Hazard, L1
Samlowski, W1
Kang, CH1
Küronya, Z1
Bodrogi, I1
Lövey, J1
Plótár, V1
Manninger, S1
Pápai, Z1
Sheen, MC1
Sheu, HM1
Jang, MY1
Chai, CY1
Wang, YW1
Wu, CF1
Kato, M1
Soga, N1
Arima, K1
Sugimura, Y1
Alnajjar, HM1
Lam, W1
Bolgeri, M1
Rees, RW1
Perry, MJ1
Watkin, NA1
Di Lorenzo, G1
Buonerba, C1
Federico, P1
Perdonà, S1
Aieta, M1
Rescigno, P1
D'Aniello, C1
Puglia, L1
Petremolo, A1
Ferro, M1
Marinelli, A1
Palmieri, G1
Sonpavde, G1
Mirone, V1
De Placido, S1
Zawar, V1
Kirloskar, M1
Chuh, A1
Leijte, JA1
Kerst, JM1
Bais, E1
Antonini, N1
Heidenreich, A1
Jakse, G1
Weismann, K1
Kassis, V1
Kattan, J1
Culine, S1
Droz, JP1
Fadel, E1
Court, B1
Perrin, JL1
Wibault, P1
Haie-Meder, C1
Arensmeier, M1
Theuring, U1
Franke, I1
Willgeroth, C1
Kühne, KH1
Fortier, LA1
Mac Harg, MA1
Pedrick, TJ1
Wheeler, W1
Riemenschneider, H1
Löwhagen, GB1
Von Krogh, G1
Bistoletti, P1
Persson, G1
Rylander, E1
Popik, MP1
Podik, OP1
Galun, MM1
Kotoulas, IG2
Cardamakis, E2
Relakis, K2
Diamantis, A1
Papathanasiou, Z2
Korantzis, A2
Mantouvalos, C1
Videtic, GM1
Ago, CT1
Winquist, EW1
Ginopoulos, P1
Metalinos, K1
Stathopoulos, E1
Michopoulos, J1
Mantouvalos, H1
Tzingounis, V1
Kitsukawa, S1
Kinn, T1
Yoshida, T1
Yonese, J1
Izutami, T1
Fukui, I1
Ishikawa, Y1
Roels, S1
Ducatelle, R1
van De Vijver, B1
De Kruif, A1
Huang, XY1
Kubota, Y1
Nakada, T1
Sasagawa, I1
Suzuki, H1
Ishigooka, M1
Roth, AD1
Berney, CR1
Rohner, S1
Allal, AS1
Morel, P1
Marti, MC1
Aapro, MS1
Alberto, P1
Netto Junior, NR1
Montellato, NI1
Srougi, M1
Rangel, PE1
de Góes, GM1
Carson, TE2
Goette, DK4
Wallin, J1
Tolia, BM1
Castro, VL1
Mouded, IM1
Newman, HR1
Kopf, AW1
Bart, RS1
Elgart, M1
DeVillez, RL1
Shammas, FV1
Ous, S1
Fossa, SD1
Hussein, AM1
Benedetto, P1
Sridhar, KS1
Abdennader, S1
Lessana-Leibowitch, M1
Pelisse, M1
Carpiniello, VL1
Malloy, TR1
Sedlacek, TV1
Zderic, SA1
Bernstein, G1
Forgaard, DM1
Miller, JE1
Bargman, H1
Kawatsu, T1
Miki, Y1
Farber, S1
McMillan, L1
Graham, JH1
Helwig, EB1
Hueser, JN1
Pugh, RP1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease: a Multicenter Randomized Controlled Trial[NCT03909646]Phase 4250 participants (Anticipated)Interventional2019-05-27Recruiting
Cabozantinib in Patients With Advanced Penile Squamous Cell Carcinoma (PSCC): an Open-label, Single-center, Phase 2, Single-arm Trial (CaboPen)[NCT03943602]Phase 237 participants (Anticipated)Interventional2019-08-01Recruiting
A Randomized Phase II Study to Evaluate the Efficacy and Safety of Cetuximab in Metastatic Penile Carcinoma[NCT02014831]Phase 20 participants (Actual)Interventional2016-02-29Withdrawn (stopped due to Industry decline to supply study drug)
A Phase II Trial of Cabazitaxel Chemotherapy in Relapsed Locally Advanced &/or Metastatic Carcinoma of the Penis[NCT03114254]Phase 217 participants (Actual)Interventional2014-12-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for fluorouracil and Penile Neoplasms

ArticleYear
Nail-like presentation of pseudoepitheliomatous keratotic and micaceous balanitis successfully treated with topical 5% 5-fluorouracil: a case report and review of the literature.
    International journal of dermatology, 2022, Volume: 61, Issue:6

    Topics: Balanitis; Fluorouracil; Humans; Male; Penile Neoplasms

2022
[Chemotherapy in male external genital organs (testicular and penile cancer)].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Chemotherapy, Adjuvant; Cisp

2013
[Penile metastasis from rectal carcinoma: a case report and literature review].
    Zhonghua nan ke xue = National journal of andrology, 2014, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluoroura

2014
[Successful multidisciplinary treatment for bladder cancer with priapism. A case report].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1998, Volume: 89, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Comb

1998
Review of erythroplasia of Queyrat and its treatment.
    Urology, 1976, Volume: 8, Issue:4

    Topics: Adult; Aged; Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penile Neoplasms; Precancerous

1976

Trials

6 trials available for fluorouracil and Penile Neoplasms

ArticleYear
Phase II trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic penis cancer (CRUK/09/001).
    British journal of cancer, 2013, Nov-12, Volume: 109, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Disease P

2013
Phase II study of docetaxel, cisplatin, and fluorouracil in patients with distantly metastatic penile cancer as first-line chemotherapy.
    Oncotarget, 2015, Oct-13, Volume: 6, Issue:31

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; China; Cisplatin; D

2015
[Treatment of condyloma acuminatum with 0.5% 5-fluorouracil-solution, A double-blind clinical trial].
    Zeitschrift fur Hautkrankheiten, 1982, Jun-01, Volume: 57, Issue:11

    Topics: Administration, Topical; Adolescent; Adult; Anus Neoplasms; Clinical Trials as Topic; Condylomata Ac

1982
Treatment of penile intraepithelial neoplasia (PIN) with interferon alpha-2a, CO2 laser (vaporization) and 5-fluorouracil 5% (5-FU).
    European journal of gynaecological oncology, 1997, Volume: 18, Issue:5

    Topics: Administration, Topical; Adult; Antineoplastic Combined Chemotherapy Protocols; Carbon Dioxide; Carc

1997
Intra-arterial chemotherapy in locally advanced or recurrent carcinomas of the penis and anal canal: an active treatment modality with curative potential.
    British journal of cancer, 2000, Volume: 83, Issue:12

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Anus Neoplasms; Arteries; Bleo

2000
[Treatment of condylomata acuminata with 5-fluorouracil].
    AMB : revista da Associacao Medica Brasileira, 1977, Volume: 23, Issue:3

    Topics: Clinical Trials as Topic; Condylomata Acuminata; Drug Evaluation; Fluorouracil; Humans; Male; Ointme

1977

Other Studies

54 other studies available for fluorouracil and Penile Neoplasms

ArticleYear
Incidence of penile intraepithelial neoplasia and treatment strategies in Sweden 2000-2019.
    BJU international, 2022, Volume: 129, Issue:6

    Topics: Adult; Carcinoma in Situ; Fluorouracil; Humans; Imiquimod; Incidence; Male; Penile Neoplasms; Sweden

2022
Topical chemotherapy for penile carcinoma in situ: Contemporary outcomes and reported toxicity.
    Urologic oncology, 2021, Volume: 39, Issue:1

    Topics: Administration, Topical; Adult; Aged; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Squamous

2021
Successful downstaging of locally recurrent penile squamous cell carcinoma with neoadjuvant nanosomal docetaxel lipid suspension (NDLS) based regimen followed by curative surgery.
    BMJ case reports, 2017, Nov-12, Volume: 2017

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco

2017
[Atypical Hemolitic Uremic Syndrome after administration of Docetaxel].
    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2018, Volume: 35, Issue:2

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineo

2018
British Association of Dermatologists' guidelines for the management of squamous cell carcinoma in situ (Bowen's disease) 2014.
    The British journal of dermatology, 2014, Volume: 170, Issue:2

    Topics: Adjuvants, Immunologic; Aminoquinolines; Antimetabolites, Antineoplastic; Bowen's Disease; Cautery;

2014
[Expression of thymidylate synthase and dihydropyrimidine dehydrogenase in penile cancer].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2013, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Dihydrouracil Dehydrogenase (NADP); Fluoro

2013
[Neoadjuvant and adjuvant chemotherapy with paclitaxel, cisplatin and 5-fluorouracil for advanced penile cancer: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2014, Volume: 60, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci

2014
Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer.
    Clinical genitourinary cancer, 2015, Volume: 13, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease-Free Survival; Docet

2015
Intraarterial chemotherapy as the first-line therapy in penile cancer.
    British journal of cancer, 2014, Sep-09, Volume: 111, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin;

2014
The treatment of penile carcinoma in situ (CIS) within a UK supra-regional network.
    BJU international, 2015, Volume: 115, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma in Situ; Circumcision, Male; Combin

2015
A Combination of Cisplatin and 5-Fluorouracil With a Taxane in Patients Who Underwent Lymph Node Dissection for Nodal Metastases From Squamous Cell Carcinoma of the Penis: Treatment Outcome and Survival Analyses in Neoadjuvant and Adjuvant Settings.
    Clinical genitourinary cancer, 2016, Volume: 14, Issue:4

    Topics: Adult; Aged; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Co

2016
Prognostic Factors of Adjuvant Taxane, Cisplatin, and 5-Fluorouracil Chemotherapy for Patients With Penile Squamous Cell Carcinoma After Regional Lymphadenectomy.
    Clinical genitourinary cancer, 2016, Volume: 14, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Drug Admi

2016
Taxanes in combination with cisplatin and fluorouracil for advanced penile cancer: preliminary results.
    European urology, 2009, Volume: 55, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fl

2009
A new neoadjuvant chemotherapy regimen for penile cancer with nodal metastases: a step forward.
    European urology, 2009, Volume: 55, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci

2009
Clinicopathological characteristics, management and outcome of metastatic penoscrotal extramammary Paget's disease.
    The British journal of dermatology, 2009, Volume: 161, Issue:3

    Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Cadherins; Docetaxel; Female; Fluorouracil; Genital

2009
Primary treatment of verrucous carcinoma of the penis with fluorouracil, cis-diamino-dichloro-platinum, and radiation therapy.
    Archives of dermatology, 2009, Volume: 145, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Verrucous

2009
Intra-arterial infusion of chemotherapy in the treatment of penile cancer.
    Japanese journal of clinical oncology, 2009, Volume: 39, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplatin; Cisplatin; Combined Modality

2009
[Metachronous metastasis from rectal adenocarcinoma to the penis--case report].
    Magyar onkologia, 2009, Volume: 53, Issue:3

    Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Comb

2009
Advanced penile verrucous carcinoma treated with intra-aortic infusion chemotherapy.
    The Journal of urology, 2010, Volume: 183, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aorta, Abdominal; Carcinoma, Verrucous; Fluorouracil;

2010
A case of local advanced penile cancer treated with multimodality therapy.
    International journal of clinical oncology, 2010, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Dose Fractionatio

2010
Proof of activity of anti-epidermal growth factor receptor-targeted therapy for relapsed squamous cell carcinoma of the penis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Aug-01, Volume: 29, Issue:22

    Topics: Amputation, Surgical; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Carcin

2011
Treatment of carcinoma in situ of the glans penis with topical chemotherapy agents.
    European urology, 2012, Volume: 62, Issue:5

    Topics: Administration, Cutaneous; Aged; Aminoquinolines; Antineoplastic Agents; Carcinoma in Situ; Fluorour

2012
Cisplatin and 5-fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis.
    BJU international, 2012, Volume: 110, Issue:11 Pt B

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; D

2012
Cisplatin and 5-fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis.
    BJU international, 2012, Volume: 110, Issue:11 Pt B

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; D

2012
Cisplatin and 5-fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis.
    BJU international, 2012, Volume: 110, Issue:11 Pt B

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; D

2012
Cisplatin and 5-fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis.
    BJU international, 2012, Volume: 110, Issue:11 Pt B

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; D

2012
'Watering-can penis' in pseudoepitheliomatous, keratotic and micaceous balanitis.
    Acta dermato-venereologica, 2004, Volume: 84, Issue:4

    Topics: Administration, Topical; Balanitis; Biopsy, Needle; Carcinoma, Verrucous; Diagnosis, Differential; F

2004
Neoadjuvant chemotherapy in advanced penile carcinoma.
    European urology, 2007, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci

2007
Editorial comment on: Neoadjuvant chemotherapy in advanced penile carcinoma.
    European urology, 2007, Volume: 52, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci

2007
[Neoadjuvant and adjuvant chemotherapy in patients with advanced penile cancer].
    Der Urologe. Ausg. A, 2007, Volume: 46, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Cisplatin; Combin

2007
Penile cancer chemotherapy: twelve years' experience at Institut Gustave-Roussy.
    Urology, 1993, Volume: 42, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplati

1993
[Topical therapy of extramammary Paget's disease].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994, Volume: 45, Issue:11

    Topics: Administration, Topical; Aged; Aged, 80 and over; Fluorouracil; Humans; Male; Paget Disease, Extrama

1994
Topical use of 5-fluorouracil for treatment of squamous cell carcinoma of the external genitalia of horses: 11 cases (1988-1992).
    Journal of the American Veterinary Medical Association, 1994, Oct-15, Volume: 205, Issue:8

    Topics: Administration, Topical; Animals; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Debridement; Fem

1994
Combined modality therapy for locally advanced penile squamous cell carcinoma.
    American journal of clinical oncology, 1993, Volume: 16, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuva

1993
[Genital papillomavirus infection. A diagnostic and therapeutic dilemma].
    Lakartidningen, 1993, Nov-17, Volume: 90, Issue:46

    Topics: Adult; Condylomata Acuminata; Diagnosis, Differential; Female; Fluorouracil; Humans; Male; Papilloma

1993
[Cancer of the penis].
    Klinichna khirurhiia, 1995, Issue:11-12

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modalit

1995
Peoscopic diagnosis of flat condyloma and penile intraepithelial neoplasia. IV. Urethral reservoir.
    Gynecologic and obstetric investigation, 1996, Volume: 41, Issue:1

    Topics: Adolescent; Adult; Carcinoma in Situ; Condylomata Acuminata; Endothelium; Female; Fluorouracil; Huma

1996
Hypercalcemia and carcinoma of the penis.
    Medical and pediatric oncology, 1997, Volume: 29, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; H

1997
Successful treatment of an equine preputial fibrosarcoma using 5-fluorouracil/evaluation of the treatment using quantitative PCNA and Ki67 (MIB 1) immunostaining. (case report).
    Zentralblatt fur Veterinarmedizin. Reihe A, 1998, Volume: 45, Issue:10

    Topics: Animals; Antimetabolites, Antineoplastic; Fibrosarcoma; Fluorouracil; Horse Diseases; Horses; Ki-67

1998
Intra-arterial infusion chemotherapy for penile carcinoma with deep inguinal lymph node metastasis.
    Urologia internationalis, 1999, Volume: 62, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin

1999
Verrucous carcinoma of the penis. Successful treatment with cryosurgery and topical fluorouracil therapy.
    Archives of dermatology, 1978, Volume: 114, Issue:10

    Topics: Administration, Topical; Carcinoma, Papillary; Cryosurgery; Fluorouracil; Humans; Male; Middle Aged;

1978
5-Fluorouracil in the treatment of penile and urethral condylomata acuminata.
    The British journal of venereal diseases, 1977, Volume: 53, Issue:4

    Topics: Condylomata Acuminata; Fluorouracil; Humans; Male; Penile Neoplasms; Podophyllin; Urethral Neoplasms

1977
Bowen's disease of shaft of penis. Successful treatment with 5-fluorouracil.
    Urology, 1976, Volume: 7, Issue:6

    Topics: Administration, Topical; Adult; Bowen's Disease; Carcinoma, Squamous Cell; Fluorouracil; Humans; Mal

1976
Skin tumor conference number 5. Erythematous plaque of the penis.
    The Journal of dermatologic surgery, 1976, Volume: 2, Issue:1

    Topics: Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penile Neoplasms

1976
Erythroplasia of Queyrat: treatment with topical 5-fluorouracil.
    Cancer, 1976, Volume: 38, Issue:4

    Topics: Administration, Topical; Adult; Aged; Carcinoma in Situ; Carcinoma, Squamous Cell; Erythroplasia; Fl

1976
Erythroplasia of Queyrat. Treatment with topically applied fluorouracil.
    JAMA, 1975, Jun-02, Volume: 232, Issue:9

    Topics: Administration, Topical; Aged; Biopsy; Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penil

1975
Cisplatin and 5-fluorouracil in advanced cancer of the penis.
    The Journal of urology, 1992, Volume: 147, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fl

1992
Cisplatin and 5-fluorouracil in advanced cancer of the penis.
    The Journal of urology, 1992, Volume: 147, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fl

1992
Cisplatin and 5-fluorouracil in advanced cancer of the penis.
    The Journal of urology, 1992, Volume: 147, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fl

1992
Cisplatin and 5-fluorouracil in advanced cancer of the penis.
    The Journal of urology, 1992, Volume: 147, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fl

1992
Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas.
    Cancer, 1990, Feb-01, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1990
Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas.
    Cancer, 1990, Feb-01, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1990
Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas.
    Cancer, 1990, Feb-01, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1990
Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas.
    Cancer, 1990, Feb-01, Volume: 65, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

1990
An atypical case of penile carcinoma in situ associated with human papillomavirus DNA type 18.
    Journal of the American Academy of Dermatology, 1989, Volume: 20, Issue:5 Pt 2

    Topics: Adult; Blotting, Southern; Carcinoma in Situ; DNA, Viral; Fluorouracil; Humans; Male; Papillomavirid

1989
Results of carbon dioxide laser therapy and topical 5-fluorouracil treatment for subclinical condyloma found by magnified penile surface scanning.
    The Journal of urology, 1988, Volume: 140, Issue:1

    Topics: Administration, Topical; Combined Modality Therapy; Condylomata Acuminata; Fluorouracil; Humans; Las

1988
Carcinoma in situ of the glans penis and distal urethra.
    The Journal of dermatologic surgery and oncology, 1986, Volume: 12, Issue:5

    Topics: Adult; Carcinoma in Situ; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Humans;

1986
Pseudoepitheliomatous, keratotic, and micaceous balanitis.
    Cutis, 1985, Volume: 35, Issue:1

    Topics: Administration, Topical; Aged; Balanitis; Carcinoma, Papillary; Fluorouracil; Humans; Male; Penile N

1985
Triple extramammary Paget's disease.
    Archives of dermatology, 1971, Volume: 104, Issue:3

    Topics: Aged; Axilla; Fluorouracil; Humans; Male; Neoplasms, Multiple Primary; Paget Disease, Extramammary;

1971
Treatment of condyloma accuminata.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Apr-22, Volume: 46, Issue:17

    Topics: Adult; Child; Condylomata Acuminata; Female; Fluorouracil; Humans; Male; Ointments; Penile Neoplasms

1972
Erythroplasia of Queyrat. A clinicopathologic and histochemical study.
    Cancer, 1973, Volume: 32, Issue:6

    Topics: Adult; Age Factors; Aged; Biopsy; Erythroplasia; Ethnicity; Female; Fluorouracil; Histocytochemistry

1973
Erythroplasia of Queyrat.
    Archives of dermatology, 1974, Volume: 110, Issue:2

    Topics: Administration, Topical; Aged; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorouracil; Humans; Ma

1974
Erythroplasia of Queyrat treated with topical 5-fluorouracil.
    The Journal of urology, 1969, Volume: 102, Issue:5

    Topics: Circumcision, Male; Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penile Neoplasms

1969