fluorouracil has been researched along with Pemphigus in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Pemphigus: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pemphigus is an autoimmune intraepidermal blistering disease mediated by autoantibodies targeting desmosomes." | 1.37 | Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen. ( Badri, T; Benmously-Mlika, R; Fenniche, S; Hammami, H; Lachkham, A; Mokhtar, I, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Callander, J | 1 |
| Ponnambath, N | 1 |
| Badri, T | 1 |
| Hammami, H | 1 |
| Lachkham, A | 1 |
| Benmously-Mlika, R | 1 |
| Mokhtar, I | 1 |
| Fenniche, S | 1 |
| Schuppli, R | 2 |
4 other studies available for fluorouracil and Pemphigus
| Article | Year |
|---|---|
Pemphigus foliaceus induced by topical 5-fluorouracil.
Topics: Aged; Female; Fluorouracil; Fusidic Acid; Humans; Hydrocortisone; Keratosis, Actinic; Pemphigus; Ste | 2016 |
Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen.
Topics: Acantholysis; Adrenal Cortex Hormones; Antigens; Antineoplastic Agents; Autoantibodies; Carcinoma; C | 2011 |
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive | 1970 |
[Treatment of dermatologic lesions using immunosuppressive agents and cytostatics].
Topics: Antineoplastic Agents; Azathioprine; Dermatomyositis; Fluorouracil; Humans; Immunosuppressive Agents | 1970 |