fluorouracil has been researched along with Pelvic Pain in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Pelvic Pain: Pain in the pelvic region of genital and non-genital origin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the association between polymorphisms of DNA repair genes and xenobiotic with acute adverse effects in locally advanced rectal cancer patients treated with neoadjuvant radiochemotherapy." | 1.46 | Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy. ( Agolli, L; Borro, M; Bracci, S; De Sanctis, V; Di Nardo, F; Enrici, RM; Falco, T; Gentile, G; Maglio, M; Minniti, G; Nicosia, L; Osti, MF; Simmaco, M; Valeriani, M, 2017) |
| "Diarrhea was the most frequent acute toxicity." | 1.31 | Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response. ( Hagihara, PF; John, WJ; Kenady, DE; Marks, G; McGrath, PC; Mohiuddin, M; Regine, WF, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osti, MF | 1 |
| Nicosia, L | 1 |
| Agolli, L | 1 |
| Gentile, G | 1 |
| Falco, T | 1 |
| Bracci, S | 1 |
| Di Nardo, F | 1 |
| Minniti, G | 1 |
| De Sanctis, V | 1 |
| Valeriani, M | 1 |
| Maglio, M | 1 |
| Borro, M | 1 |
| Simmaco, M | 1 |
| Enrici, RM | 1 |
| Mohiuddin, M | 1 |
| Regine, WF | 1 |
| John, WJ | 1 |
| Hagihara, PF | 1 |
| McGrath, PC | 1 |
| Kenady, DE | 1 |
| Marks, G | 1 |
2 other studies available for fluorouracil and Pelvic Pain
| Article | Year |
|---|---|
Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiothera | 2017 |
Preoperative chemoradiation in fixed distal rectal cancer: dose time factors for pathological complete response.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Diarrhea | 2000 |