Page last updated: 2024-10-27

fluorouracil and Parotid Neoplasms

fluorouracil has been researched along with Parotid Neoplasms in 17 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Parotid Neoplasms: Tumors or cancer of the PAROTID GLAND.

Research Excerpts

ExcerptRelevanceReference
" A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C."3.66Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy. ( Budd, GT; Groppe, CW, 1983)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199010 (58.82)18.7374
1990's2 (11.76)18.2507
2000's3 (17.65)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takemoto, K1
Miyahara, N1
Chikuie, N1
Hamamoto, T1
Ishino, T1
Ueda, T1
Takeno, S1
Yamazaki, H1
Ota, Y1
Aoki, T1
Kaneko, A1
GEVAUDAN, P1
BONNEAU, H1
CHARREL, J1
DESIRE, G1
HELSPER, JT1
DEMOSS, EV1
BAKER, RR1
GAERTNER, RA1
Furusawa, J1
Mizumati, T1
Iizuka, K1
Perez-Fidalgo, JA1
Chirivella, I1
Laforga, J1
Colio, JM1
Blanes, MD1
Baydal, R1
Roselló, S1
De-la-Morena, E1
Lluch, A1
Budd, GT1
Groppe, CW1
Furuse, S1
Mizushima, Y1
Mino, T1
Yoshida, Y1
Nakagawa, H1
Asou, S1
Wakagi, K1
Kobayashi, M1
Raut, V1
Golchin, K1
Anderson, N1
Primrose, WJ1
Yamada, H1
Inoue, K1
Horikoshi, N1
Mukaiyama, T1
Ogawa, M1
Kuraishi, Y1
Sparwald, E1
Müllensiefen, C1
Lange, G1
Slanina, I1
The, KK1
Lokich, JJ1
Skarin, AT1
Nathanson, L1
Hall, TC1
Schilling, A1
Miller, S1
Glupe, J1
Kraus, H1
Wannenmacher, E1
Zeligman, I1
Lutzner, MA1
Scott, CI1

Reviews

1 review available for fluorouracil and Parotid Neoplasms

ArticleYear
[5-Fluorouracil, adriamycin, and mitomycin C (FAM) combination chemotherapy in adenocarcinoma of the parotid gland].
    Gan no rinsho. Japan journal of cancer clinics, 1989, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Doxorubicin;

1989

Trials

1 trial available for fluorouracil and Parotid Neoplasms

ArticleYear
Concurrent combination chemotherapy of human solid tumors: experience with a three-drug regimen and review of the literature.
    Cancer research, 1969, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Neoplasms; Carcinoma; Child; Child, Preschool; Clinical T

1969

Other Studies

15 other studies available for fluorouracil and Parotid Neoplasms

ArticleYear
Efficacy of anti-PD-1 therapy in a patient with brain metastasis of parotid carcinoma: A case report.
    Auris, nasus, larynx, 2019, Volume: 46, Issue:5

    Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Brain Ne

2019
Lung metastases of epithelial-myoepithelial carcinoma of the parotid gland successfully treated with chemotherapy: a case report.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013, Volume: 71, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Docetaxel; Fluorouracil

2013
[ON THE BEHAVIOR OF PRIMARY CULTURES OF MIXED PAROTID TUMORS, IN THE PRESENCE OF CYTOTOXIC PRODUCTS].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Adenoma, Pleomorphic; Cyclophosphamide; Fluorouracil; Humans; Mechlorethamine; Parotid Neoplasms; Ph

1964
REGIONAL INTRA-ARTERIAL INFUSION OF 5-FLUOROURACIL FOR CANCER.
    Surgery, 1964, Volume: 56

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Carcinoma, Squamous Cell; Female; Fluorouracil; Glioblast

1964
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
    The Journal of surgical research, 1965, Volume: 5

    Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; H

1965
[A case of parotid carcinoma with hepatic metastasis that responded remarkably to combination chemotherapy of docetaxel, cisplatin and 5-fluorouracil].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:13

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Drug Administr

2003
Parotid gland metastasis of a breast cancer.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2007, Volume: 9, Issue:4

    Topics: Anastrozole; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Al

2007
Adenoid cystic carcinoma of the salivary gland. Sustained complete response to chemotherapy.
    Cancer, 1983, Feb-15, Volume: 51, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Adenoid Cystic; Doxorubicin; Drug

1983
[A combination chemotherapy with CDDP and 5-FU effective for pulmonary metastases in a case of parotid gland carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1996, Volume: 23, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Thera

1996
Metastatic astrocytoma in the parotid.
    Cytopathology : official journal of the British Society for Clinical Cytology, 2002, Volume: 13, Issue:3

    Topics: Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biopsy, Needle; Brain Neop

2002
[Methodological aspects on the histological evaluation of subrenal capsule assay (SRCA)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyclophosphamide; Cyclosporins; Female; Fluoroura

1990
[Clinical results after synchronised radiotherapy in 21 cases of human malignomas (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1974, Volume: 53, Issue:6

    Topics: Adult; Aged; Facial Neoplasms; Female; Fluorouracil; Follow-Up Studies; Germany, West; Humans; Laryn

1974
Five-drug combination chemotherapy for disseminated adenocarcinoma.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:6

    Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Drug

1972
[Combined cytostatic and irradiation treatment of head and neck tumors using the synchronization effect].
    HNO, 1972, Volume: 20, Issue:1

    Topics: Aged; Cobalt Isotopes; Ear Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; M

1972
Xeroderma pigmentosum.
    Birth defects original article series, 1971, Volume: 7, Issue:8

    Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Eyelid Neoplasms; Female;

1971