fluorouracil has been researched along with Papilledema in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Papilledema: Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turner, LD | 1 |
| Harrison, JD | 1 |
| Greenfield, DS | 1 |
| Wanichwecharungruang, B | 1 |
| Liebmann, JM | 1 |
| Ritch, R | 1 |
2 other studies available for fluorouracil and Papilledema
| Article | Year |
|---|---|
Bilateral optic disc oedema and associated optic neuropathy in the setting of FOLFOX chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Leucovor | 2013 |
Pseudotumor cerebri appearing with unilateral papilledema after trabeculectomy.
Topics: Acetazolamide; Adult; Antimetabolites; Carbonic Anhydrase Inhibitors; Female; Fluorouracil; Fundus O | 1997 |