fluorouracil has been researched along with Pancreatic Diseases in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Pancreatic Diseases: Pathological processes of the PANCREAS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histological and electron microscopic study of the pancreas and biochemical determination of pancreatic enzymes in blood serum were performed in animals with experimental pancreonecrosis and after the treatment with 5-fluorouracil." | 7.66 | [Morphology of experimental pancreonecrosis following treatment with 5-fluorouracil]. ( Nishanov, KhT; Pomelov, VS; Titova, GP, 1981) |
| "Histological and electron microscopic study of the pancreas and biochemical determination of pancreatic enzymes in blood serum were performed in animals with experimental pancreonecrosis and after the treatment with 5-fluorouracil." | 3.66 | [Morphology of experimental pancreonecrosis following treatment with 5-fluorouracil]. ( Nishanov, KhT; Pomelov, VS; Titova, GP, 1981) |
| "The anticancer drugs, like 5-Fluorouracil, which are believed to interfere with enzyme protein synthesis in the exocrine cells of pancreas were administered intravenously to fifteen patients with various pancreatic diseases." | 3.65 | Clinical effects of anticancer drugs to pancreatic diseases as protein synthesis inhibitors. ( Kawamura, M; Kinami, Y; Miyazaki, I; Sakane, Y; Sugii, M, 1976) |
| "Pancreatic panniculitis is characterized by subcutaneous fat necrosis and is a rare presentation of an underlying pancreatic disease, appearing in approximately 2-3% of all patients with a pancreatic disease." | 1.72 | Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report. ( Besselink, MG; Busch, OR; Haenen, SM; Post, HC; Roshani, S; Sarasqueta, AF; Tol, JAMG; van der Linden, MMD; van Steen, SCJ; Wilmink, JW; Wolkerstorfer, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haenen, SM | 1 |
| Tol, JAMG | 1 |
| van Steen, SCJ | 1 |
| Busch, OR | 1 |
| Sarasqueta, AF | 1 |
| Roshani, S | 1 |
| Wolkerstorfer, A | 1 |
| van der Linden, MMD | 1 |
| Wilmink, JW | 1 |
| Post, HC | 1 |
| Besselink, MG | 1 |
| Titova, GP | 1 |
| Pomelov, VS | 1 |
| Nishanov, KhT | 1 |
| Barone, RM | 1 |
| Kinami, Y | 1 |
| Miyazaki, I | 1 |
| Kawamura, M | 1 |
| Sugii, M | 1 |
| Sakane, Y | 1 |
4 other studies available for fluorouracil and Pancreatic Diseases
| Article | Year |
|---|---|
Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report.
Topics: Acinar Cells; Aged; Carcinoma, Acinar Cell; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Li | 2022 |
[Morphology of experimental pancreonecrosis following treatment with 5-fluorouracil].
Topics: Acute Disease; alpha-Amylases; Amidinotransferases; Animals; Fluorouracil; Male; Microscopy, Electro | 1981 |
Prevention of the pancreatic complications after surgical procedures of the pancreas: invited commentary.
Topics: Fluorouracil; Humans; Pancreas; Pancreatic Diseases; Postoperative Complications; Protein Biosynthes | 1978 |
Clinical effects of anticancer drugs to pancreatic diseases as protein synthesis inhibitors.
Topics: Acute Disease; Adult; Amylases; Chronic Disease; Cysts; Female; Fluorouracil; Humans; Male; Middle A | 1976 |