fluorouracil has been researched along with Palatal Neoplasms in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Palatal Neoplasms: Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article presents a patient affected with epidermoid carcinoma of the soft palate who developed a dilated myocardiopathy with aortic embolism and fatal left cardiac failure after treatment with cisplatin (100 mg/m2, day 1) and 5-fluorouracil (1 g/m2/day i." | 3.67 | Lethal cardiac toxicity after cisplatin and 5-fluorouracil chemotherapy. Report of a case with necropsy study. ( Almenarez, J; Blázquez, J; Diaz-Rubio, E; Fariña, J; Furió, V; Martin, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HOWE, CD | 1 |
| FLETCHER, GH | 1 |
| SAMUELS, ML | 1 |
| SUIT, HD | 1 |
| Cheriparambil, KM | 1 |
| Vasireddy, H | 1 |
| Kuruvilla, A | 1 |
| Gambarin, B | 1 |
| Makan, M | 1 |
| Saul, BI | 1 |
| Martin, M | 1 |
| Diaz-Rubio, E | 1 |
| Furió, V | 1 |
| Blázquez, J | 1 |
| Almenarez, J | 1 |
| Fariña, J | 1 |
| Couture, J | 1 |
| Deschênes, L | 1 |
| Takayama, I | 1 |
| Ando, Y | 1 |
| Katsumi, Y | 2 |
| Shozu, R | 1 |
| Takeyama, I | 1 |
| Ando, K | 1 |
| Ozu, R | 1 |
6 other studies available for fluorouracil and Palatal Neoplasms
| Article | Year |
|---|---|
COMBINED 5-FLUOROURACIL AND COBALT IRRADIATION EVALUATED BY DOUBLE BLIND TECHNIQUE.
Topics: Cobalt; Cobalt Isotopes; Double-Blind Method; Epiglottis; Fluorouracil; Humans; Neoplasms; Palatal N | 1964 |
Acute reversible cardiomyopathy and thromboembolism after cisplatin and 5-fluorouracil chemotherapy--a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cardiomyopathies; Cisplati | 2000 |
Lethal cardiac toxicity after cisplatin and 5-fluorouracil chemotherapy. Report of a case with necropsy study.
Topics: Aortic Diseases; Carcinoma, Squamous Cell; Cardiomyopathy, Dilated; Cisplatin; Embolism; Fluorouraci | 1989 |
Intra-arterial infusion--an adjuvant to the treatment of oral carcinoma.
Topics: Adult; Aged; Carotid Artery, External; Catheterization; Evaluation Studies as Topic; Floxuridine; Fl | 1972 |
[Therapy of malignant tumor of the head and neck region].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Mi | 1971 |
[Chemotherapy of malignant tumors in otorhinolaryngology--combined treatment with antitumor agents and MDS bby intra-arterial route].
Topics: Dextrans; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Maxillary Neoplasms; Middle Aged | 1971 |