fluorouracil has been researched along with Pain, Intractable in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "48 patients with metastatic breast cancer and extensive bone involvement were treated with salm-calcitonin and polychemo-therapy or hormonal treatment." | 2.65 | [Calcitonin in bone-metastasizing breast carcinoma. Results of a pilot study]. ( Beaufort, F; Gölles, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kasliwal, MK | 1 |
| Tan, LA | 1 |
| O'Toole, JE | 1 |
| Beaufort, F | 1 |
| Gölles, M | 1 |
| Beyer, JH | 1 |
| von Heyden, HW | 1 |
| Bartsch, HH | 1 |
| Klee, M | 1 |
| Nagel, GA | 1 |
| Schuster, R | 1 |
| von Romatowski, HJ | 1 |
| Sonoo, H | 1 |
| Shimozuma, K | 1 |
| Kurebayashi, J | 1 |
| Ohta, K | 1 |
| Kiyono, T | 1 |
| Breul, J | 1 |
| Jakse, G | 1 |
| Forster, G | 1 |
| Lampel, A | 1 |
| Rohani, A | 1 |
| Hartung, R | 1 |
| Estes, NC | 1 |
| Morphis, JG | 1 |
| Hornback, NB | 1 |
| Jewell, WR | 1 |
1 review available for fluorouracil and Pain, Intractable
| Article | Year |
|---|---|
[Systemic therapy, pain relief and quality of life of breast cancer patients with bone metastasis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Clinical Trials as | 1995 |
2 trials available for fluorouracil and Pain, Intractable
| Article | Year |
|---|---|
[Calcitonin in bone-metastasizing breast carcinoma. Results of a pilot study].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Calci | 1984 |
5-Fluorouracil versus folinic acid and 5-fluorouracil in advanced, hormone-resistant prostate cancer: a prospective randomized pilot trial.
Topics: Aged; Androgens; Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Drug Therapy, Combinati | 1997 |
3 other studies available for fluorouracil and Pain, Intractable
| Article | Year |
|---|---|
Intradural tumor recurrence after resection of extradural metastasis: a rare but potential complication of intraoperative durotomy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Signet Ring Cell; Colorectal Neoplasms; C | 2014 |
Intra-arterial perfusion therapy with 5-fluorouracil in patients with metastatic colorectal carcinoma and intractable pelvic pain.
Topics: Adult; Colonic Neoplasms; Combined Modality Therapy; Dose-Response Relationship, Drug; Female; Fluor | 1983 |
Intraarterial chemotherapy and hyperthermia for pain control in patients with recurrent rectal cancer.
Topics: Aged; Female; Fluorouracil; Humans; Hyperthermia, Induced; Infusions, Intra-Arterial; Male; Middle A | 1986 |