Page last updated: 2024-10-27

fluorouracil and Ovarian Diseases

fluorouracil has been researched along with Ovarian Diseases in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Ovarian Diseases: Pathological processes of the OVARY.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vehmanen, L1
Saarto, T1
Elomaa, I1
Mäkelä, P1
Välimäki, M1
Blomqvist, C1

Trials

1 trial available for fluorouracil and Ovarian Diseases

ArticleYear
Long-term impact of chemotherapy-induced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment.
    European journal of cancer (Oxford, England : 1990), 2001, Volume: 37, Issue:18

    Topics: Absorptiometry, Photon; Administration, Oral; Adult; Amenorrhea; Antimetabolites; Antineoplastic Com

2001