Page last updated: 2024-10-27

fluorouracil and Osteolysis

fluorouracil has been researched along with Osteolysis in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.

Research Excerpts

ExcerptRelevanceReference
"Female breast cancer is one of the major causes of death among women while male breast cancer is relatively uncommon and accounts for about 1% of all breast cancers in both sexes."1.34Male breast cancer with mandibular metastasis. A case report. ( Amaddeo, P; Barbaglio, A; Faldi, F; Fontana, S; Ghilardi, R; Pericotti, S, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fontana, S1
Ghilardi, R1
Barbaglio, A1
Amaddeo, P1
Faldi, F1
Pericotti, S1

Other Studies

1 other study available for fluorouracil and Osteolysis

ArticleYear
Male breast cancer with mandibular metastasis. A case report.
    Minerva stomatologica, 2007, Volume: 56, Issue:4

    Topics: Aged; Androstadienes; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplast

2007