Page last updated: 2024-10-27

fluorouracil and Orthopedic Disorders

fluorouracil has been researched along with Orthopedic Disorders in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhao, C1
Zobitz, ME1
Sun, YL1
Predmore, KS1
Amadio, PC1
An, KN1
Moran, SL1

Other Studies

1 other study available for fluorouracil and Orthopedic Disorders

ArticleYear
Surface treatment with 5-fluorouracil after flexor tendon repair in a canine in vivo model.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:11

    Topics: Administration, Topical; Animals; Antimetabolites; Dogs; Fluorouracil; Musculoskeletal Diseases; Ten

2009