fluorouracil has been researched along with Orbital Neoplasms in 17 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Orbital Neoplasms: Neoplasms of the bony orbit and contents except the eyeball.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a durable (12-month) response to capecitabine monotherapy, shown clinically, by MRI, and by cerebrospinal fluid analysis, in a patient with leptomeningeal metastasis from breast cancer." | 7.72 | Durable response of breast cancer leptomeningeal metastasis to capecitabine monotherapy. ( Remer, SE; Rogers, LR; Tejwani, S, 2004) |
| "A 55-year-old Asian Indian woman who had recurrent sebaceous gland carcinoma of the left lower eyelid with orbital extension and regional lymph node metastasis was treated with neoadjuvant chemotherapy, using a combination of carboplatin and 5-fluorouracil." | 3.73 | Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis. ( Burman, S; Honavar, SG; Murthy, R; Naik, MN; Reddy, VA; Vemuganti, GK, 2005) |
| "We report a durable (12-month) response to capecitabine monotherapy, shown clinically, by MRI, and by cerebrospinal fluid analysis, in a patient with leptomeningeal metastasis from breast cancer." | 3.72 | Durable response of breast cancer leptomeningeal metastasis to capecitabine monotherapy. ( Remer, SE; Rogers, LR; Tejwani, S, 2004) |
| "A patient with recurrent breast cancer, who was diagnosed with eyelid metastasis as a part of systemic metastases and in whom systemic chemotherapy was markedly effective, is reported." | 2.39 | Eyelid metastasis from breast cancer showing marked response to chemotherapy. ( Abe, K; Adachi, I; Kaneko, A; Narabayashi, M; Tokue, Y; Tsuda, H; Watanabe, T; Yin, DF; Zhang, GJ, 1995) |
| "Many cases with metastatic hepatic cancer have a poor prognosis because of the appearance of extrahepatic lesions in spite of the fact that a partial response can be obtained by hepatic arterial infusion chemotherapy." | 1.30 | [Appearance of extrahepatic lesions in the superior lip and orbit of a patient with liver metastases of gastric cancer following partial response by hepatic arterial infusion chemotherapy]. ( Hasegawa, K; Ichikawa, T; Kawai, S; Kirihara, M; Kume, S; Maruo, H; Tominaga, S, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Li, R | 1 |
| Tian, S | 1 |
| Zhu, Y | 1 |
| Zhu, W | 1 |
| Wang, S | 1 |
| Gogia, A | 1 |
| Pushker, N | 1 |
| Sen, S | 1 |
| Bakhshi, S | 1 |
| De Stefani, A | 1 |
| Boffano, P | 1 |
| Bongioannini, G | 1 |
| Nair, AG | 1 |
| Kaliki, S | 1 |
| Mishra, DK | 1 |
| Reddy, VA | 2 |
| Naik, MN | 2 |
| Fukui, T | 1 |
| Yoshioka, T | 1 |
| Takano, J | 1 |
| Fujishima, S | 1 |
| Otake, S | 1 |
| Orii, T | 1 |
| Sato, T | 1 |
| Sasaki, Y | 1 |
| Nishise, S | 1 |
| Takeda, H | 1 |
| Kawata, S | 1 |
| Takamura, H | 1 |
| Mutyala, V | 1 |
| Bains, S | 1 |
| Patil, C | 1 |
| Madhavarao, B | 1 |
| Sullivan, TJ | 1 |
| Rogers, LR | 1 |
| Remer, SE | 1 |
| Tejwani, S | 1 |
| Murthy, R | 1 |
| Honavar, SG | 1 |
| Burman, S | 1 |
| Vemuganti, GK | 1 |
| Copcu, E | 1 |
| Sivrioglu, N | 1 |
| Baytekin, C | 1 |
| Er, S | 1 |
| Koc, B | 1 |
| Char, DH | 1 |
| Crawford, JB | 1 |
| Bellman, B | 1 |
| Gregory, NA | 1 |
| Silvers, D | 1 |
| Fountain, KS | 1 |
| Zhang, GJ | 1 |
| Adachi, I | 1 |
| Yin, DF | 1 |
| Narabayashi, M | 1 |
| Tokue, Y | 1 |
| Watanabe, T | 1 |
| Kaneko, A | 1 |
| Tsuda, H | 1 |
| Abe, K | 1 |
| Maruo, H | 1 |
| Kirihara, M | 1 |
| Hasegawa, K | 1 |
| Kawai, S | 1 |
| Tominaga, S | 1 |
| Ichikawa, T | 1 |
| Kume, S | 1 |
| Lubec, G | 1 |
| Szalay, S | 1 |
| Bergman, RB | 1 |
| Pfeiffer, P | 1 |
| Madsen, EL | 1 |
| Hansen, O | 1 |
| May, O | 1 |
2 reviews available for fluorouracil and Orbital Neoplasms
| Article | Year |
|---|---|
Topical therapies for periorbital cutaneous malignancies: indications and treatment regimens.
Topics: Administration, Topical; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, S | 2012 |
Eyelid metastasis from breast cancer showing marked response to chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Lobular | 1995 |
1 trial available for fluorouracil and Orbital Neoplasms
| Article | Year |
|---|---|
Effect of prophylactic sucralfate suspension on stomatitis induced by cancer chemotherapy. A randomized, double-blind cross-over study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Double-Blind Meth | 1990 |
14 other studies available for fluorouracil and Orbital Neoplasms
| Article | Year |
|---|---|
Management of orbital invasion in sinonasal squamous cell carcinoma: 15 years' experience.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol | 2020 |
Avoidance of exenteration in orbital sebaceous gland carcinoma with neoadjuvant chemotherapy.
Topics: Adenocarcinoma, Sebaceous; Cisplatin; Eye Evisceration; Eyelid Neoplasms; Fluorouracil; Humans; Male | 2013 |
The management of an orbital diffuse large B-cell lymphoma.
Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined C | 2014 |
Neoadjuvant chemotherapy for invasive squamous cell carcinoma of the conjunctiva: A case report.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Conjunct | 2015 |
[A case of primary orbital adenocarcinoma responding to chemoradiation].
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Combined Modality | 2009 |
Bilateral acute ptosis leading to the diagnosis of a presumed metastatic gastric adenocarcinoma.
Topics: Acute Disease; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Blepharoptosis; Capec | 2012 |
Durable response of breast cancer leptomeningeal metastasis to capecitabine monotherapy.
Topics: Adult; Antimetabolites, Antineoplastic; Brain Neoplasms; Breast Neoplasms; Capecitabine; Deoxycytidi | 2004 |
Neoadjuvant chemotherapy in the management of sebaceous gland carcinoma of the eyelid with regional lymph node metastasis.
Topics: Adenocarcinoma, Sebaceous; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Eyelid Neopl | 2005 |
How can we decide on orbital exenteration for second eye in a patient with basal cell carcinoma?
Topics: Aged; Antineoplastic Agents; Carcinoma, Basal Cell; Cheek; Dose Fractionation, Radiation; Fluorourac | 2006 |
Orbital invasion despite topical anti-metabolite therapy for conjunctival carcinoma.
Topics: Administration, Topical; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Con | 2008 |
Sweat gland carcinoma with metastases to the skin: response to 5-fluorouracil chemotherapy.
Topics: Aged; Bone Marrow Diseases; Bone Neoplasms; Carcinoma, Signet Ring Cell; Facial Neoplasms; Fluoroura | 1995 |
[Appearance of extrahepatic lesions in the superior lip and orbit of a patient with liver metastases of gastric cancer following partial response by hepatic arterial infusion chemotherapy].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Epirubicin; Fluo | 1998 |
[5-fluorouracil inhibits bacterial collagenase and the collagenolytic system of a human rhabdomyosarcoma].
Topics: Cells, Cultured; Clostridium; Collagen; Drug Evaluation, Preclinical; Enzyme Activation; Fluorouraci | 1979 |
[Experiences in the treatment of 2 patients with xeroderma pigmentosum].
Topics: Adolescent; Adult; Brain Neoplasms; Female; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Ne | 1976 |