fluorouracil has been researched along with Orbital Diseases in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Orbital Diseases: Diseases of the bony orbit and contents except the eyeball.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There was no recurrence (in six cases) and no side-effects seen in group A at final follow-up of 18." | 1.39 | Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket. ( Bodh, SA; Goel, R; Kamal, S; Kumar, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamal, S | 1 |
| Kumar, S | 1 |
| Goel, R | 1 |
| Bodh, SA | 1 |
| Gataa, IS | 1 |
| Nader, NH | 1 |
| Abdallah, DT | 1 |
| Lebowitz, D | 1 |
| Gürses-Ozden, R | 1 |
| Rothman, RF | 1 |
| Liebmann, JM | 1 |
| Tello, C | 1 |
| Ritch, R | 1 |
1 review available for fluorouracil and Orbital Diseases
| Article | Year |
|---|---|
Massive Craniofacial Gorham Disease Treated Successfully by Cisplatin and 5-Fluorouracil With Ten Years of Follow-Up: A Case Report and Literature Review.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil; | 2016 |
2 other studies available for fluorouracil and Orbital Diseases
| Article | Year |
|---|---|
Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket.
Topics: Adult; Anophthalmos; Antimetabolites; Conjunctiva; Contracture; Eye Enucleation; Eye, Artificial; Fl | 2013 |
Late-onset bleb-related panophthalmitis with orbital abscess caused by Pseudomonas stutzeri.
Topics: Abscess; Aged; Eye Enucleation; Eye Infections, Bacterial; Fluorouracil; Humans; Male; Orbital Disea | 2001 |