Page last updated: 2024-10-27

fluorouracil and Orbital Diseases

fluorouracil has been researched along with Orbital Diseases in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Orbital Diseases: Diseases of the bony orbit and contents except the eyeball.

Research Excerpts

ExcerptRelevanceReference
"There was no recurrence (in six cases) and no side-effects seen in group A at final follow-up of 18."1.39Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket. ( Bodh, SA; Goel, R; Kamal, S; Kumar, S, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kamal, S1
Kumar, S1
Goel, R1
Bodh, SA1
Gataa, IS1
Nader, NH1
Abdallah, DT1
Lebowitz, D1
Gürses-Ozden, R1
Rothman, RF1
Liebmann, JM1
Tello, C1
Ritch, R1

Reviews

1 review available for fluorouracil and Orbital Diseases

ArticleYear
Massive Craniofacial Gorham Disease Treated Successfully by Cisplatin and 5-Fluorouracil With Ten Years of Follow-Up: A Case Report and Literature Review.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil;

2016

Other Studies

2 other studies available for fluorouracil and Orbital Diseases

ArticleYear
Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:12

    Topics: Adult; Anophthalmos; Antimetabolites; Conjunctiva; Contracture; Eye Enucleation; Eye, Artificial; Fl

2013
Late-onset bleb-related panophthalmitis with orbital abscess caused by Pseudomonas stutzeri.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2001, Volume: 119, Issue:11

    Topics: Abscess; Aged; Eye Enucleation; Eye Infections, Bacterial; Fluorouracil; Humans; Male; Orbital Disea

2001