fluorouracil has been researched along with Oral Submucous Fibrosis in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Oral Submucous Fibrosis: Irreversible FIBROSIS of the submucosal tissue of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with head and neck cancer who chewed betel quid habitually seem to experience more severe chemotherapy-induced mucositis in our clinical practice." | 1.30 | Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent. ( Chen, IH; Chen, JS; Liao, CT; Su, CL; Wang, CH; Wang, HM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HM | 1 |
| Wang, CH | 1 |
| Chen, JS | 1 |
| Su, CL | 1 |
| Liao, CT | 1 |
| Chen, IH | 1 |
1 other study available for fluorouracil and Oral Submucous Fibrosis
| Article | Year |
|---|---|
Impact of oral submucous fibrosis on chemotherapy-induced mucositis for head and neck cancer in a geographic area in which betel quid chewing is prevalent.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Areca; Asia, Southeastern; Cisplatin; F | 1999 |