fluorouracil has been researched along with Oculopharyngeal Dystrophy in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López-Estévez, S | 1 |
| Ferrer, G | 1 |
| Torres-Torronteras, J | 1 |
| Mansilla, MJ | 1 |
| Casacuberta-Serra, S | 1 |
| Martorell, L | 1 |
| Hirano, M | 1 |
| Martí, R | 1 |
| Barquinero, J | 1 |
1 other study available for fluorouracil and Oculopharyngeal Dystrophy
| Article | Year |
|---|---|
Thymidine phosphorylase is both a therapeutic and a suicide gene in a murine model of mitochondrial neurogastrointestinal encephalomyopathy.
Topics: Animals; Capecitabine; Cell Line, Tumor; Combined Modality Therapy; Deoxycytidine; Disease Models, A | 2014 |