Page last updated: 2024-10-27

fluorouracil and Nevi, Melanocytic

fluorouracil has been researched along with Nevi, Melanocytic in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Six of the patients' dysplastic melanocytic nevi were treated with topical fluorouracil."1.26Topical chemotherapy of dysplastic melanocytic nevi with 5% fluorouracil. ( Bondi, EE; Clark, WH; Elder, D; Greene, MH; Guerry, D, 1981)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bogenrieder, T1
Weitzel, C1
Schölmerich, J1
Landthaler, M1
Stolz, W1
Rodriguez-Blanco, I1
Ginarte Val, M1
Peteiro, C1
Toribio, J1
Hagstrom, WJ1
Faibisoff, B1
Soltani, K1
Robson, MC1
Bondi, EE1
Clark, WH1
Elder, D1
Guerry, D1
Greene, MH1
Bak, A1
Zeligman, I1
Lutzner, MA1
Scott, CI1

Other Studies

6 other studies available for fluorouracil and Nevi, Melanocytic

ArticleYear
Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: a lesson for the pathogenesis of malignant melanoma?
    Dermatology (Basel, Switzerland), 2002, Volume: 205, Issue:2

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Colorectal Neoplasms

2002
Multiple atypical naevi after systemic 5-fluorouracil.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:6

    Topics: Adenocarcinoma; Aged; Back; Biopsy; Diagnosis, Differential; Fluorouracil; Humans; Male; Nevus, Pigm

2007
Dysplastic nevus syndrome (B-K mole syndrome).
    Plastic and reconstructive surgery, 1983, Volume: 71, Issue:2

    Topics: Dermabrasion; Fluorouracil; Humans; Male; Middle Aged; Neoplasms, Multiple Primary; Nevus, Pigmented

1983
Topical chemotherapy of dysplastic melanocytic nevi with 5% fluorouracil.
    Archives of dermatology, 1981, Volume: 117, Issue:2

    Topics: Administration, Topical; Adult; Female; Fluorouracil; Humans; Melanoma; Nevus, Pigmented

1981
[A case of Cogan-Reese syndrome (iris nevus syndrome)].
    Klinika oczna, 1997, Volume: 99, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; F

1997
Xeroderma pigmentosum.
    Birth defects original article series, 1971, Volume: 7, Issue:8

    Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Eyelid Neoplasms; Female;

1971