fluorouracil has been researched along with Nevi, Melanocytic in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six of the patients' dysplastic melanocytic nevi were treated with topical fluorouracil." | 1.26 | Topical chemotherapy of dysplastic melanocytic nevi with 5% fluorouracil. ( Bondi, EE; Clark, WH; Elder, D; Greene, MH; Guerry, D, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bogenrieder, T | 1 |
| Weitzel, C | 1 |
| Schölmerich, J | 1 |
| Landthaler, M | 1 |
| Stolz, W | 1 |
| Rodriguez-Blanco, I | 1 |
| Ginarte Val, M | 1 |
| Peteiro, C | 1 |
| Toribio, J | 1 |
| Hagstrom, WJ | 1 |
| Faibisoff, B | 1 |
| Soltani, K | 1 |
| Robson, MC | 1 |
| Bondi, EE | 1 |
| Clark, WH | 1 |
| Elder, D | 1 |
| Guerry, D | 1 |
| Greene, MH | 1 |
| Bak, A | 1 |
| Zeligman, I | 1 |
| Lutzner, MA | 1 |
| Scott, CI | 1 |
6 other studies available for fluorouracil and Nevi, Melanocytic
| Article | Year |
|---|---|
Eruptive multiple lentigo-maligna-like lesions in a patient undergoing chemotherapy with an oral 5-fluorouracil prodrug for metastasizing colorectal carcinoma: a lesson for the pathogenesis of malignant melanoma?
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Colorectal Neoplasms | 2002 |
Multiple atypical naevi after systemic 5-fluorouracil.
Topics: Adenocarcinoma; Aged; Back; Biopsy; Diagnosis, Differential; Fluorouracil; Humans; Male; Nevus, Pigm | 2007 |
Dysplastic nevus syndrome (B-K mole syndrome).
Topics: Dermabrasion; Fluorouracil; Humans; Male; Middle Aged; Neoplasms, Multiple Primary; Nevus, Pigmented | 1983 |
Topical chemotherapy of dysplastic melanocytic nevi with 5% fluorouracil.
Topics: Administration, Topical; Adult; Female; Fluorouracil; Humans; Melanoma; Nevus, Pigmented | 1981 |
[A case of Cogan-Reese syndrome (iris nevus syndrome)].
Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; F | 1997 |
Xeroderma pigmentosum.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Eyelid Neoplasms; Female; | 1971 |