fluorouracil has been researched along with Neuromuscular Diseases in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Neuromuscular Diseases: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capecitabine plus oxaliplatin combination (XELOX) is the first-line treatment in metastatic colorectal cancer." | 3.78 | Nerve, muscle and heart acute toxicity following oxaliplatin and capecitabine treatment. ( Alì, G; Calabrese, R; Lenzi, P; Moretti, P; Orsucci, D; Petrozzi, L; Pizzanelli, C; Ricci, G; Siciliano, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kounis, NG | 1 |
| Soufras, GD | 1 |
| Orsucci, D | 2 |
| Pizzanelli, C | 2 |
| Moretti, P | 2 |
| Siciliano, G | 2 |
| Alì, G | 1 |
| Calabrese, R | 1 |
| Ricci, G | 1 |
| Lenzi, P | 1 |
| Petrozzi, L | 1 |
3 other studies available for fluorouracil and Neuromuscular Diseases
| Article | Year |
|---|---|
Nerve, muscle and heart acute toxicity following oxaliplatin and capecitabine treatment.
Topics: Cardiomyopathies; Deoxycytidine; Female; Fluorouracil; Humans; Neuromuscular Diseases; Organoplatinu | 2013 |
Reply to: Nerve, muscle and heart acute toxicity following oxaliplatin and capecitabine treatment.
Topics: Cardiomyopathies; Deoxycytidine; Female; Fluorouracil; Humans; Neuromuscular Diseases; Organoplatinu | 2013 |
Nerve, muscle and heart acute toxicity following oxaliplatin and capecitabine treatment.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cardiomyopathies; Colo | 2012 |