fluorouracil has been researched along with Neuroectodermal Tumors, Primitive, Peripheral in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Neuroectodermal Tumors, Primitive, Peripheral: A group of highly cellular primitive round cell neoplasms which occur extracranially in soft tissue and bone and are derived from embryonal neural crest cells. These tumors occur primarily in children and adolescents and share a number of characteristics with EWING SARCOMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiden, PL | 1 |
| Yarington, CT | 1 |
| Richardson, RG | 1 |
| Polonowski, JM | 1 |
| Brasnu, D | 1 |
| Roux, FX | 1 |
| Bassot, V | 1 |
| Heros, DO | 1 |
| Hochberg, FH | 1 |
3 other studies available for fluorouracil and Neuroectodermal Tumors, Primitive, Peripheral
| Article | Year |
|---|---|
Olfactory neuroblastoma. Chemotherapy and radiotherapy for extensive disease.
Topics: Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Humans; Middle Aged; Nasopharyngeal Neop | 1984 |
Esthesioneuroblastoma. Complete tumor response after induction chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil; Humans; Inf | 1990 |
Treatment of esthesioneuroblastoma with chemotherapy: a report of two cases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Humans; Male | 1988 |