Page last updated: 2024-10-27

fluorouracil and Neoplasms, Squamous Cell

fluorouracil has been researched along with Neoplasms, Squamous Cell in 38 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Neoplasms, Squamous Cell: Neoplasms of the SQUAMOUS EPITHELIAL CELLS. The concept does not refer to neoplasms located in tissue composed of squamous elements.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the efficacy of concurrent oral capecitabine with accelerated hypofractionated radical radiotherapy in locally advanced squamous cell carcinoma of the head and neck (SCCHN)."9.15Synchronous chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck using capecitabine: a single-centre, open-label, single-group phase II study. ( Birzgalis, A; Homer, J; Jegannathen, A; Lee, L; Mais, K; Ryder, WD; Slevin, N; Sykes, A; Yap, B, 2011)
"To evaluate the efficacy of concurrent oral capecitabine with accelerated hypofractionated radical radiotherapy in locally advanced squamous cell carcinoma of the head and neck (SCCHN)."5.15Synchronous chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck using capecitabine: a single-centre, open-label, single-group phase II study. ( Birzgalis, A; Homer, J; Jegannathen, A; Lee, L; Mais, K; Ryder, WD; Slevin, N; Sykes, A; Yap, B, 2011)
"Patients with advanced head and neck cancer who were treated only with hyperfractionated irradiation received 125 cGy twice daily, for a total of 7500 cGy."2.69Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. ( Albers, ME; Brizel, DM; Fisher, SR; George, SL; Hars, V; Huang, AT; Prosnitz, LR; Richtsmeier, WJ; Scher, RL, 1998)
" Individualized 5-FU dosing to obtain higher 5-FU plasma concentrations may be indicated."2.68Pharmacodynamics of fluorouracil-based induction chemotherapy in advanced head and neck cancer. ( Athanasiadis, I; Dolan, ME; Haraf, DJ; Kies, MS; Kozloff, M; Malone, D; Mick, R; Ratain, MJ; Vokes, EE; Weichselbaum, RR, 1996)
"Topical treatment of skin cancer may therefore be more appropriate in certain instances."2.66Topical treatments for skin cancer. ( Boyle, GM; Cullen, JK; Parsons, PG; Simmons, JL, 2020)
"The majority of the head and neck cancers are squamous cell carcinomas, which commonly overexpress the EGF receptor (EGFR)."2.47Cetuximab in the treatment of squamous cell carcinoma of the head and neck. ( Specenier, P; Vermorken, JB, 2011)
"Although a decrease in distant metastases has frequently been observed, an improvement in survival from induction has been difficult to demonstrate."2.43Does induction chemotherapy have a role in the management of locoregionally advanced squamous cell head and neck cancer? ( Adelstein, DJ; Leblanc, M, 2006)
"5 fluorouracil therapy was terminated and the patients were shifted to interferon therapy subsequently."1.51Severe necrotising inflammatory skin reaction to topical 5-fluorouracil. ( Gokhale, NS, 2019)
"Ten patients had disease progression."1.38Chemotherapy with modified docetaxel, cisplatin, and 5-fluorouracil in patients with metastatic head and neck cancer. ( Bi, CP; Chang, TH; Chen, MK; Lai, GM; Lin, JT; Liu, MT; Wang, JW, 2012)
"Topical 5-FU, as a sole or combined therapy, must be considered a long-term safe and effective treatment for patients affected by OSSN."1.37Topical 1% 5-fluorouracil in ocular surface squamous neoplasia: a long-term safety study. ( Alemany-Rubio, E; Lazzarini, D; Midena, E; Parrozzani, R; Urban, F, 2011)
"Furthermore, HNSCC-driven squamospheres appeared to be chemoresistant to cisplatin, 5-fluorouracil (FU), paclitaxel and doxetaxel, and showed increased levels of ABCG2, one of the ATP-binding cassette (ABC) transporters."1.37Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas. ( Cha, YY; Jin, X; Kim, H; Kim, SH; Lim, YC; Oh, SY, 2011)
"The growing number of patients with head and neck cancer is a reason to search for new effective treatment strategies."1.36[Taxan induction chemotherapy and concomitant chemoradiotherapy with cisplatin in patients with locally advanced head and neck cancer--early results]. ( Chilimoniuk, M; Maksimowicz, T; Olszewska, E, 2010)
"77."1.33Osteoprotegerin and bone mass in squamous cell head and neck cancer patients. ( Hernández, JL; Macías, JG; Olmos, JM; Rivera, F; Valero, C; Vega, ME, 2006)
"Nine (18%) have died of anal cancer."1.32Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost. ( Melcher, AA; Sebag-Montefiore, D, 2003)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.26)18.2507
2000's16 (42.11)29.6817
2010's18 (47.37)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Ko, JC1
Chen, JC1
Wei, CL1
Liu, LL1
Chien, CC1
Huang, IH1
Hsieh, JM1
Chiang, CS1
Tseng, PY1
Cheng, HH1
Tsao, YC1
Lin, YW1
Cullen, JK1
Simmons, JL1
Parsons, PG1
Boyle, GM1
Gokhale, NS1
Fujimoto, Y1
Nakashima, Y1
Sasaki, S1
Jogo, T1
Hirose, K1
Edahiro, K1
Korehisa, S1
Taniguchi, D1
Kudou, K1
Nakaji, YU1
Nakanishi, R1
Ando, K1
Saeki, H1
Oki, E1
Fujiwara, M1
Oda, Y1
Maehara, Y1
Li, B1
Hong, P1
Zheng, CC1
Dai, W1
Chen, WY1
Yang, QS1
Han, L1
Tsao, SW1
Chan, KT1
Lee, NPY1
Law, S1
Xu, LY1
Li, EM1
Chan, KW1
Qin, YR1
Guan, XY1
Lung, ML1
He, QY1
Xu, WW1
Cheung, AL1
Kim, S1
Jary, M1
Mansi, L1
Benzidane, B1
Cazorla, A1
Demarchi, M1
Nguyen, T1
Kaliski, A1
Delabrousse, E1
Bonnetain, F1
Letondal, P1
Bosset, JF1
Valmary-Degano, S1
Borg, C1
Rodriguez, CP1
Adelstein, DJ4
Rybicki, LA2
Saxton, JP1
Lorenz, RR1
Wood, BG2
Strome, M2
Esclamado, RM2
Lavertu, P2
Carroll, MA2
Sepulveda, R1
Pe'er, J1
Midena, E2
Seregard, S1
Dua, HS1
Singh, AD1
Clavel, S1
Fortin, B1
Després, P1
Donath, D1
Soulières, D1
Khaouam, N1
Charpentier, D1
Bélair, M1
Guertin, L1
Nguyen-Tan, PF1
Parrozzani, R1
Lazzarini, D1
Alemany-Rubio, E1
Urban, F1
Has, C1
Burger, B1
Volz, A1
Kohlhase, J1
Bruckner-Tuderman, L1
Itin, P1
Jegannathen, A1
Mais, K1
Sykes, A1
Lee, L1
Yap, B1
Birzgalis, A1
Homer, J1
Ryder, WD1
Slevin, N1
Kogashiwa, Y1
Yamauchi, K1
Nagafuji, H1
Matsuda, T1
Tsubosaka, T1
Karaho, T1
Maruyama, T1
Kohno, N1
Wisniewska-Jarosinska, M1
Sliwinski, T1
Kasznicki, J1
Kaczmarczyk, D1
Krupa, R1
Bloch, K1
Drzewoski, J1
Chojnacki, J1
Blasiak, J1
Morawiec-Sztandera, A1
Lim, YC1
Oh, SY1
Cha, YY1
Kim, SH1
Jin, X1
Kim, H1
Rudkin, AK1
Muecke, JS1
Chilimoniuk, M1
Olszewska, E1
Maksimowicz, T1
Specenier, P1
Vermorken, JB3
Guigay, J1
Mesia, R1
Trigo, JM1
Keilholz, U1
Kerber, A1
Bethe, U1
Picard, M1
Brummendorf, TH1
Lin, JT1
Lai, GM1
Chang, TH1
Liu, MT1
Bi, CP1
Wang, JW1
Chen, MK1
Endrizzi, B1
Ahmed, RL1
Ray, T1
Dudek, A1
Lee, P1
Li, Y1
Adams, GL1
Wagner, H1
Kish, JA1
Ensley, JF1
Schuller, DE1
Forastiere, AA2
Gilbert, J1
Melcher, AA1
Sebag-Montefiore, D1
McHam, SA1
Schrijvers, D1
Van Herpen, C1
Kerger, J1
Joosens, E1
Van Laer, C1
Awada, A1
Van den Weyngaert, D1
Nguyen, H1
Le Bouder, C1
Castelijns, JA1
Kaanders, J1
De Mulder, P1
Pignon, JP1
Syz, N1
Posner, M1
Olivares, R1
Le Lann, L1
Yver, A1
Dunant, A1
Lewin, F1
Dalley, DN1
Paccagnella, A1
Taylor, SG1
Domenge, C1
Bourhis, J1
Mazumdar, M1
Stone, DU1
Butt, AL1
Chodosh, J1
Sarbia, M1
Stahl, M1
von Weyhern, C1
Weirich, G1
Pühringer-Oppermann, F1
Tishler, RB1
Posner, MR1
Norris, CM1
Mahadevan, A1
Sullivan, C1
Goguen, L1
Wirth, LJ1
Costello, R1
Case, M1
Stowell, S1
Sammartino, D1
Busse, PM1
Haddad, RI1
Leblanc, M1
Valero, C1
Olmos, JM1
Rivera, F1
Hernández, JL1
Vega, ME1
Macías, JG1
Itoh, Y1
Fuwa, N1
Ijichi, K1
Adachi, M1
Hasegawa, Y1
Ogawa, T1
Nakamura, H1
Kudoh, A1
Yasui, Y1
Murakami, S1
Ishizaki, K1
Weinberg, JM1
Vokes, EE1
Mick, R1
Kies, MS1
Dolan, ME1
Malone, D1
Athanasiadis, I1
Haraf, DJ1
Kozloff, M1
Weichselbaum, RR1
Ratain, MJ1
Brizel, DM1
Albers, ME1
Fisher, SR1
Scher, RL1
Richtsmeier, WJ1
Hars, V1
George, SL1
Huang, AT1
Prosnitz, LR1
Knowling, M1
Browman, G1
Siu, L1
Khoo, K1
Cooke, A1
Tannock, I1
Klaassen, D1
Cripps, C1
Goss, G1
Matthews, S1
Clarke, R1
Seymour, L1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of the Clinical Value of a Docetaxel, Cisplatin and 5-fluorouracil (DCF) Strategy Adapted to Patients for the Management of Metastatic or Locally Advanced Anal Resistant Radiochemotherapy Squamous Cell Anal Carcinoma.[NCT02402842]Phase 270 participants (Actual)Interventional2014-09-30Completed
Efficacy and Safety of Avatrombopag in Cancer Patients With Thrombocytopenia Induced by Targeted Therapy and Immunotherapy Combination Treatment[NCT04896528]Phase 230 participants (Anticipated)Interventional2021-06-06Recruiting
A Pilot Study of Additional Chinese Formula for Concurrent Chemoradiotherapy in Oral Cavity Cancer Patients[NCT05590650]Phase 121 participants (Actual)Interventional2018-07-07Completed
Comparison Between Two Regimens of Chemotherapy Concurrent With Radiotherapy in Locally Advanced Head and Neck Cancer[NCT03998696]Phase 460 participants (Actual)Interventional2017-07-01Completed
Phase I Study of Cabazitaxel - Platinum Fluorouracil Induction Chemotherapy in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck[NCT01379339]Phase 140 participants (Actual)Interventional2011-04-30Completed
Quarterback 22: A Phase II Clinical Trial of Sequential Therapy and De-Intensified Chemoradiotherapy for Locally Advanced HPV Positive Oropharynx Cancer[NCT02945631]43 participants (Actual)Interventional2016-04-25Active, not recruiting
The Quarterback Trial: A Randomized Phase III Clinical Trial Comparing Reduced and Standard Radiation Therapy Doses for Locally Advanced HPV Positive Oropharynx Cancer[NCT01706939]Phase 323 participants (Actual)Interventional2012-09-01Active, not recruiting
Observational Study on the Investigation of the Molecular Mechanism and Clinical Significance of the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.[NCT01927354]100 participants (Anticipated)Observational2012-12-31Recruiting
Radiosensitization With a COX-2 Inhibitor (Celecoxib), With Chemoradiation for Cancer of the Head and Neck[NCT00581971]Phase 1/Phase 230 participants (Actual)Interventional2002-09-30Completed
A Clinical Outcomes Protocol of Photon/Proton Beam Radiation Therapy for Oropharyngeal Cancers[NCT00797446]10 participants (Actual)Observational2007-09-30Terminated (stopped due to Slow enrollment, feasibility issues)
The Effect of Prophylactic Swallowing Exercises on Head and Neck Cancer Patients[NCT01349309]26 participants (Actual)Interventional2007-06-30Completed
Concurrent Angiogenic and EGFR Blockade in Conjunction With Curative Intent Chemoradiation for Locally Advanced Head and Neck Cancer[NCT00140556]Early Phase 128 participants (Actual)Interventional2005-08-31Completed
Primary Surgery Vs Primary Chemoradiation for Oropharyngeal Cancer (Scope Trial) - A Phase II/III Integrated Design Randomized Control Trial[NCT05144100]Phase 2/Phase 3498 participants (Anticipated)Interventional2021-12-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Biomarkers Predictive of Failure

To determine biomarkers predictive of failure with either reduced or standard dose radiotherapy. (NCT01706939)
Timeframe: at 5 years

Interventionbiomarkers (Number)
Reduced Dose Radiation0
Standard Dose Radiation0

Change in MD Anderson Dysphagia Inventory (MDADI) From Baseline

MDADI is a questionnaire of 20 questions and contains a global subscale, and three other categories of questions (emotional, functional, and physical). The scores are summed and a mean score is calculated. This mean score was multiplied by 20 to obtain a score, with a range of 0 (extremely low functioning) to 100 (high functioning). Thus, a higher MDADI score represented better day-to-day functioning and better QOL. (NCT01706939)
Timeframe: Baseline and 5 years

Interventionscore on a scale (Mean)
Reduced Dose Radiation-8.12
Standard Dose Radiation-8.93

Change in Xerostomia Questionnaire (XQ)

XQ is a nine questions survey developed specifically for xerostomia symptoms. The scores are summed and a mean score is calculated on a scale of 0 (low xerostomia interference) to 10 (high xerostomia interference). A lower or negative score reflects a better quality of life compared to baseline. (NCT01706939)
Timeframe: Baseline and 5 years

Interventionscore on a scale (Mean)
Reduced Dose Radiation2.18
Standard Dose Radiation4.38

Number of Participants With Acute Toxicity of Chemoradiotherapy (CRT)

Number of participants with acute toxicity treated with reduced or standard dose CRT. (NCT01706939)
Timeframe: at 5 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation3
Standard Dose Radiation1

Number of Participants With Local-regional Control

Local-regional control (LRC) at 3 years in patients with advanced HPV related oropharynx cancer or unknown primary treated with reduced or standard dose radiation. (NCT01706939)
Timeframe: at 3 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation10
Standard Dose Radiation7

Number of Participants With Overall Survival at 5 Years

Overall Survival (OS) 5 years treated with reduced or standard dose CRT. (NCT01706939)
Timeframe: at 5 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation10
Standard Dose Radiation7

Change in European Organization for Research and Treatment of Cancer Questionnaire for Head and Neck (EORTC HN)

The EORTC Head and Neck module was specifically designed and validated for head and neck cancer patients. This 35-item questionnaire contains 7 symptom scales (pain, swallowing, senses, speech, social eating, social contact, and sexuality), 6 single-item scales (difficulties of teeth, mouth opening, dry mouth, sticky saliva, coughing, and feeling ill), and 5 items about the additional use of pain medicine, nutritional supplements, and feeding tube and changes in body weight. All items were transformed to scales from 0 to 100, and divided into respective sub-scores of global health (GHS), functional (FS), and symptom scale (SS). Subscales from 0-100. A high score on global health and functional scale represents a better level of functioning, whereas a high score on a symptom scale and head and neck module indicates more severe symptoms. (NCT01706939)
Timeframe: Baseline and 5 years

,
Interventionscore on a scale (Mean)
EORTC GHSEORTC FSEORTC SSEORTC HN
Reduced Dose Radiation5.955.14-3.91-2.80
Standard Dose Radiation-30.56-6.3314.978.97

Change in MD Anderson Symptom Inventory Symptom Inventory and Severity (MDASI-HN SI and SS)

"MD Anderson Symptom Inventory Symptom Inventory and Severity (MDASI-HN SI and SS) MDASI Head and Neck is a site-specific MDASI module which includes the core MDASI 13 symptom severity items (SS) and 6 symptom interference items (SI), alongside 9 items relevant to head and neck cancer. The scores are summed and a mean score is calculated on a scale of 0 (low severity or interference) to 10 (high severity or complete interference). In order to calculate the mean score, a majority of the subscale's items must have been completed.~A lower or negative score reflects a better quality of life compared to baseline." (NCT01706939)
Timeframe: Baseline and 5 years

,
Interventionscore on a scale (Mean)
MDASI-HN SIMDASI-HN SS
Reduced Dose Radiation0.640.52
Standard Dose Radiation1.561.48

Number of Participants With Progression Free Survival (PFS)

Progression free survival (PFS) at 5 years in patients with advanced HPV related oropharynx cancer, nasopharynx cancer or unknown primary treated with reduced or standard dose radiation. (NCT01706939)
Timeframe: at 3 and 5 years

,
InterventionParticipants (Count of Participants)
at 3 yearsat 5 years
Reduced Dose Radiation1010
Standard Dose Radiation77

Response as Evaluated by Recurrence of Diseases

Evaluate the response to concurrent celecoxib, carboplatin, paclitaxel, and radiotherapy in the treatment of locally advanced SSC of the head and neck. Response is determined by local control only, local and distant metastasis, distant metastasis only, second primary, and surgical salvage. (NCT00581971)
Timeframe: 2 years from end of treatment (Radiation therapy)

InterventionParticipants (Number)
Local Control OnlyLocal Control and Distant MetastasisDistant Metastatsis OnlySecondary Primary - Site UnknownSurgical Salvage
Recurrence62123

Toxicity of Celecoxib With Concurrent Weekly Chemotherapy and Radiotherapy in the Treatment of Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck.

Particpants experiencing Acute Toxicities > Grade 3 (NCT00581971)
Timeframe: 2 years from radiation therapy

Interventionparticipants (Number)
HematologicDermatitisMucositis/Dysphagia
Acute Toxicity12716

Tumor Resolution

Complete response (resolution) of tumor on clinical exam. (NCT00140556)
Timeframe: Within 30 days of completing RT

InterventionParticipants (Number)
Entire Study Population25

Reviews

8 reviews available for fluorouracil and Neoplasms, Squamous Cell

ArticleYear
Topical treatments for skin cancer.
    Advanced drug delivery reviews, 2020, 01-01, Volume: 153

    Topics: Administration, Cutaneous; Antineoplastic Agents; Carcinoma, Basal Cell; Clinical Trials as Topic; D

2020
Chemoradiotherapy for Solitary Skeletal Muscle Metastasis from Oesophageal Cancer: Case Report and Brief Literature Review.
    Anticancer research, 2017, Volume: 37, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous

2017
Topical chemotherapy for ocular surface squamous neoplasia: current status.
    The British journal of ophthalmology, 2010, Volume: 94, Issue:5

    Topics: Administration, Topical; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplasti

2010
Cetuximab in the treatment of squamous cell carcinoma of the head and neck.
    Expert review of anticancer therapy, 2011, Volume: 11, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothe

2011
Organ preservation trials for laryngeal cancer.
    Otolaryngologic clinics of North America, 2002, Volume: 35, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Fluorouracil;

2002
Adjusting for patient selection suggests the addition of docetaxel to 5-fluorouracil-cisplatin induction therapy may offer survival benefit in squamous cell cancer of the head and neck.
    Anti-cancer drugs, 2004, Volume: 15, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials, Phase II as Topic; Clini

2004
Does induction chemotherapy have a role in the management of locoregionally advanced squamous cell head and neck cancer?
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jun-10, Volume: 24, Issue:17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Head and Neck Neoplasms; Hu

2006
Topical therapy for actinic keratoses: current and evolving therapies.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:1

    Topics: Administration, Cutaneous; Administration, Topical; Aminoquinolines; Antineoplastic Agents; Carcinom

2006

Trials

9 trials available for fluorouracil and Neoplasms, Squamous Cell

ArticleYear
Synchronous chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck using capecitabine: a single-centre, open-label, single-group phase II study.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2011, Volume: 23, Issue:2

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma; Carcinoma, Squamous Cell; Com

2011
Phase I study of S-1 plus nedaplatin in patients with advanced/recurrent head and neck cancer.
    Chemotherapy, 2010, Volume: 56, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplatin

2010
Phase I/II trial of cilengitide with cetuximab, cisplatin and 5-fluorouracil in recurrent and/or metastatic squamous cell cancer of the head and neck: findings of the phase I part.
    British journal of cancer, 2011, May-24, Volume: 104, Issue:11

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap

2011
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jan-01, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2003
Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I-II feasibility study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2004, Volume: 15, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docet

2004
Concurrent weekly docetaxel and concomitant boost radiation therapy in the treatment of locally advanced squamous cell cancer of the head and neck.
    International journal of radiation oncology, biology, physics, 2006, Jul-15, Volume: 65, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carb

2006
Pharmacodynamics of fluorouracil-based induction chemotherapy in advanced head and neck cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorour

1996
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer.
    The New England journal of medicine, 1998, Jun-18, Volume: 338, Issue:25

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1998
A National Cancer Institute of Canada clinical trials group phase II study of eniluracil (776C85) and oral 5-fluorouracil in patients with advanced squamous cell head and neck cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2001, Volume: 12, Issue:7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Canada

2001

Other Studies

21 other studies available for fluorouracil and Neoplasms, Squamous Cell

ArticleYear
Downregulation of p38 MAPK Activation and Radiation-Sensitive 52 Expression Enhances 5-Fluorouracil and Erlotinib-Induced Cytotoxicity in Human Lung Squamous Cells.
    Pharmacology, 2021, Volume: 106, Issue:11-12

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Down-Regulation; Erlotinib Hydrochloride; Fl

2021
Severe necrotising inflammatory skin reaction to topical 5-fluorouracil.
    Indian journal of ophthalmology, 2019, Volume: 67, Issue:12

    Topics: Administration, Ophthalmic; Antimetabolites, Antineoplastic; Conjunctival Neoplasms; Drug Eruptions;

2019
Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance.
    Theranostics, 2019, Volume: 9, Issue:6

    Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Esophageal Neoplasms; F-Box Proteins; Fluorouracil

2019
DCF (docetaxel, cisplatin and 5-fluorouracil) chemotherapy is a promising treatment for recurrent advanced squamous cell anal carcinoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cisplatin; Disease-Free

2013
Clinical predictors of larynx preservation after multiagent concurrent chemoradiotherapy.
    Head & neck, 2008, Volume: 30, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Fema

2008
Enteral feeding during chemoradiotherapy for advanced head-and-neck cancer: a single-institution experience using a reactive approach.
    International journal of radiation oncology, biology, physics, 2011, Mar-01, Volume: 79, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Carcinoma, Squa

2011
Topical 1% 5-fluorouracil in ocular surface squamous neoplasia: a long-term safety study.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Conjunctival Neoplas

2011
Mild clinical phenotype of Kindler syndrome associated with late diagnosis and skin cancer.
    Dermatology (Basel, Switzerland), 2010, Volume: 221, Issue:4

    Topics: Aged; Aminoquinolines; Antineoplastic Agents; Basement Membrane; Blister; Carcinoma, Basal Cell; Cry

2010
Cytotoxicity and genotoxicity of capecitabine in head and neck cancer and normal cells.
    Molecular biology reports, 2011, Volume: 38, Issue:6

    Topics: Capecitabine; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival; Comet Assay; Deoxycytidine; D

2011
Cancer stem cell traits in squamospheres derived from primary head and neck squamous cell carcinomas.
    Oral oncology, 2011, Volume: 47, Issue:2

    Topics: Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Female; Flow Cyt

2011
Adjuvant 5-fluorouracil in the treatment of localised ocular surface squamous neoplasia.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:7

    Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Eye Neoplasms; Female; Fluorouracil; Humans; Ma

2011
[Taxan induction chemotherapy and concomitant chemoradiotherapy with cisplatin in patients with locally advanced head and neck cancer--early results].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010, Volume: 29, Issue:174

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell; Cisplat

2010
Chemotherapy with modified docetaxel, cisplatin, and 5-fluorouracil in patients with metastatic head and neck cancer.
    Advances in therapy, 2012, Volume: 29, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Disease Progression; Docetax

2012
Capecitabine to reduce nonmelanoma skin carcinoma burden in solid organ transplant recipients.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, B

2013
Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost.
    British journal of cancer, 2003, May-06, Volume: 88, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Dise

2003
Who merits a neck dissection after definitive chemoradiotherapy for N2-N3 squamous cell head and neck cancer?
    Head & neck, 2003, Volume: 25, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Female; Fluoroura

2003
Ocular surface squamous neoplasia: a standard of care survey.
    Cornea, 2005, Volume: 24, Issue:3

    Topics: Administration, Topical; Antineoplastic Agents; Biopsy; Combined Modality Therapy; Conjunctival Neop

2005
The prognostic significance of genetic polymorphisms (Methylenetetrahydrofolate Reductase C677T, Methionine Synthase A2756G, Thymidilate Synthase tandem repeat polymorphism) in multimodally treated oesophageal squamous cell carcinoma.
    British journal of cancer, 2006, Jan-30, Volume: 94, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Antineoplastic Agents; Combined Modality

2006
Osteoprotegerin and bone mass in squamous cell head and neck cancer patients.
    Calcified tissue international, 2006, Volume: 78, Issue:6

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bone Density; Bone Matrix; Bone Remode

2006
Retrospective analysis: concurrent chemoradiotherapy using protracted continuous infusion of low-dose cisplatin and 5-fluorouracil for T2N0 glottic cancer.
    Radiation medicine, 2006, Volume: 24, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cisplatin; Female; Flu

2006
Pretreatment with 5-FU enhances cisplatin cytotoxicity in head and neck squamous cell carcinoma cells.
    Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:5

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle; Cell Line, Tu

2008