Page last updated: 2024-10-27

fluorouracil and Neoplasms, Skull

fluorouracil has been researched along with Neoplasms, Skull in 12 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Twenty-five squamous cell carcinomas, 1 melanoma, 2 basocellular carcinomas and 2 adenoid cystic carcinomas were treated."1.33[The outcome of treatments for carcinoma of the external auditory canal]. ( Delalande, C; Dumas, G; Lavieille, JP; Reyt, E; Righini, Ch; Schmerber, S; Soriano, E, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kun, M1
Xinxin, Z1
Feifan, Z1
Lin, M1
KOOP, CE1
Schmerber, S1
Righini, Ch1
Soriano, E1
Delalande, C1
Dumas, G1
Reyt, E1
Lavieille, JP1
Brasnu, D1
Laccourreye, O1
Bassot, V1
Laccourreye, L1
Naudo, P1
Roux, FX1
Danikas, D1
Theodorou, SJ1
Arvanitis, ML1
Zinterhofer, LM1
Rienzo, AA1
Nibu, K1
Sugasawa, M1
Asai, M1
Ichimura, K1
Mochiki, M1
Terahara, A1
Kawahara, N1
Asato, H1
Cappellano, RS1
Cintra, RA1
Weidner, F1
Stolte, M1
Zimmermann, G1
Boeckl, O1
Kühböck, J1
Pokorny, D1
Steinbach, K1
Eggerth, G1
Freckman, HA1
Gordan, GS1
Wessler, S1
Avioli, LV1

Reviews

1 review available for fluorouracil and Neoplasms, Skull

ArticleYear
Unresectable Recurrent Squamous Cell Carcinoma of the Temporal Bone Treated by Induction Chemotherapy Followed by Concurrent Chemo-Reirradiation: A Case Report and Review of the Literature.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2015, Volume: 36, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiothera

2015

Other Studies

11 other studies available for fluorouracil and Neoplasms, Skull

ArticleYear
CURRENT MANAGEMENT OF NEPHROBLASTOMA AND NEUROBLASTOMA.
    American journal of surgery, 1964, Volume: 107

    Topics: Antineoplastic Agents; Child; Dactinomycin; Fluorouracil; Infant; Infant, Newborn; Kidney Neoplasms;

1964
[The outcome of treatments for carcinoma of the external auditory canal].
    Revue de laryngologie - otologie - rhinologie, 2005, Volume: 126, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth

2005
Cisplatin-based neoadjuvant chemotherapy and combined resection for ethmoid sinus adenocarcinoma reaching and/or invading the skull base.
    Archives of otolaryngology--head & neck surgery, 1996, Volume: 122, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant;

1996
Malar metastasis from rectal carcinoma: a case report.
    The American surgeon, 1999, Volume: 65, Issue:12

    Topics: Adenocarcinoma; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fatal Outcome; Female

1999
Results of multimodality therapy for squamous cell carcinoma of maxillary sinus.
    Cancer, 2002, Mar-01, Volume: 94, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co

2002
[Continuous intra-arterial antiblastic chemotherapy in the treatment of rhinopharyngeal tumors invading the skull base. Association with radiotherapy].
    AMB : revista da Associacao Medica Brasileira, 1975, Volume: 21, Issue:4

    Topics: Carcinoma, Squamous Cell; Fluorouracil; Humans; Injections, Intra-Arterial; Middle Aged; Neoplasm Me

1975
[Multicentric metatypical scalp basalioma (ulcus terebans) with perforation into the cranium].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1974, Volume: 25, Issue:2

    Topics: Aged; Autopsy; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Palliative Care; Scalp; Skin Neo

1974
[Therapy of advanced tumors with 5-fluoro-uracil].
    Wiener medizinische Wochenschrift (1946), 1969, Sep-13, Volume: 119, Issue:37

    Topics: Femoral Neoplasms; Fluorouracil; Humans; Injections, Intra-Arterial; Injections, Intravenous; Intest

1969
[Polychemotherapy of malignant tumors and hemoblastoses].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1968, Volume: 49, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinom

1968
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
    American journal of surgery, 1972, Volume: 124, Issue:4

    Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Art

1972
Calusterone in the therapy for advanced breast cancer.
    JAMA, 1972, Jan-24, Volume: 219, Issue:4

    Topics: Adenocarcinoma; Axilla; Bone Neoplasms; Breast Neoplasms; Castration; Drug Synergism; Female; Fluoro

1972