Page last updated: 2024-10-27

fluorouracil and Necrolytic Migratory Erythema

fluorouracil has been researched along with Necrolytic Migratory Erythema in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Necrolytic Migratory Erythema: Recurrent cutaneous manifestation of GLUCAGONOMA characterized by necrolytic polycyclic migratory lesions with scaling borders. It is associated with elevated secretion of GLUCAGON by the tumor. Other conditions with elevated serum glucagon levels such as HEPATIC CIRRHOSIS may also result in similar skin lesions, which are referred to as pseudoglucagonoma syndrome.

Research Excerpts

ExcerptRelevanceReference
"Necrolytic migratory erythema is an obligatory paraneoplastic syndrome."1.39Necrolytic migratory erythema in a patient with neuroendocrine carcinoma. ( Enk, AH; Gronau, M; Hassel, JC; Jäger, D, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gronau, M1
Jäger, D1
Enk, AH1
Hassel, JC1

Other Studies

1 other study available for fluorouracil and Necrolytic Migratory Erythema

ArticleYear
Necrolytic migratory erythema in a patient with neuroendocrine carcinoma.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Capecitabine; Carcinoma, Neur

2013