fluorouracil has been researched along with Myocardial Infarction in 49 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil, a widely used drug in cancer treatment, is known to have cardiotoxic effects: chest pain with ECG changes, arrhythmias, arterial hypertension or hypotension, myocardial infarction, cardiogenic shock and sudden death have been described in the literature." | 7.72 | Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases. ( Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B, 2003) |
| "A case of 5-fluorouracil-induced cardiotoxicity, possibly due to coronary artery spasm, and mimicking acute anterolateral myocardial infarction is presented and discussed." | 7.71 | 5-fluorouracil-induced cardiotoxicity mimicking myocardial infarction: a case report. ( Campbell, NP; McGlinchey, PG; Webb, ST, 2001) |
| "A 53-year-old female patient was treated with combined radiochemotherapy with 5-fluorouracil (5-FU) because of adenocarcinoma of the lung." | 7.69 | [5-fluorouracil: cause of a fatal myocardial infarction in combined radiochemotherapy?]. ( Härle, M; Jungius, KP; Maurer, U, 1996) |
| "Three cases of cardiotoxicity manifested by chest pain, tachycardia, respiratory distress, and electrocardiographic changes simulating acute myocardial infarction or ischemia were observed during the course of combination chemotherapy with etoposide, cisplatin, and continuous infusion of 5-fluorouracil in patients with advanced non-small cell lung cancer." | 7.68 | Electrocardiographic changes simulating acute myocardial infarction or ischemia associated with combination chemotherapy with etoposide, cisplatin, and 5-fluorouracil. ( Kim, SH; Lee, JS; Lee, KH, 1990) |
| "Capecitabine is an orally available chemotherapeutic agent that is converted to 5-fluorouracil (5-FU) after absorbtion." | 5.38 | Acute myocardial infarction after capecitabine treatment: not always vasospasm is responsible. ( Celiker, E; Eren, M; Güvenç, TS; Ilhan, E; Ozcan, KS, 2012) |
| "Capecitabine is a chemotherapeutic prodrug that is metabolised to 5-fluorouracil." | 5.35 | Coronary spasm induced by capecitabine mimicks ST elevation myocardial infarction. ( Curzen, NP; Ferchow, L; Hobson, A; Scott, PA, 2008) |
| "To investigate cardiac toxicity associated with breast radiation therapy (RT) at 10-year follow-up in BCIRG-001, a phase 3 trial comparing adjuvant anthracycline chemotherapy (fluorouracil, doxorubicin, and cyclophosphamide) with anthracycline-taxane chemotherapy (docetaxel, doxorubicin, and cyclophosphamide) in women with lymph node-positive early breast cancer." | 5.24 | Effect of Breast Irradiation on Cardiac Disease in Women Enrolled in BCIRG-001 at 10-Year Follow-Up. ( Gerber, NK; Perez, CA; Tam, M; Vega, RM; Wu, SP, 2017) |
| "Two cases of 5-Fluorouracil (5FU) cardiotoxicity, chest pain with changes in ECG the former, and myocardial infarction the latter, are described." | 4.77 | [Cardiotoxicity of 5-fluorouracil. Personal cases and review of the literature]. ( Beretta, GD; Borsotti, E; Calasso, F; Carini, L; De Ceglia, S; Labianca, R; Rocca, A; Segalini, G, 1987) |
| "Two cases of 5-fluorouracil cardiotoxicity, resulting in one patient in myocardial infarction, are described." | 4.76 | 5-Fuorouracil cardiotoxicity. ( Guindani, A; Pagnoni, A; Villani, F, 1979) |
| " Two of the patients could not be treated with 5-FU any more because they had developed a myocardial ischemia, which was most likely caused by fluorouracil." | 3.78 | 5-FU-induced cardiac toxicity--an underestimated problem in radiooncology? ( Hautmann, MG; Kölbl, O; Steger, F, 2012) |
| "5-Fluorouracil, a widely used drug in cancer treatment, is known to have cardiotoxic effects: chest pain with ECG changes, arrhythmias, arterial hypertension or hypotension, myocardial infarction, cardiogenic shock and sudden death have been described in the literature." | 3.72 | Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases. ( Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B, 2003) |
| "A case of 5-fluorouracil-induced cardiotoxicity, possibly due to coronary artery spasm, and mimicking acute anterolateral myocardial infarction is presented and discussed." | 3.71 | 5-fluorouracil-induced cardiotoxicity mimicking myocardial infarction: a case report. ( Campbell, NP; McGlinchey, PG; Webb, ST, 2001) |
| "A 53-year-old female patient was treated with combined radiochemotherapy with 5-fluorouracil (5-FU) because of adenocarcinoma of the lung." | 3.69 | [5-fluorouracil: cause of a fatal myocardial infarction in combined radiochemotherapy?]. ( Härle, M; Jungius, KP; Maurer, U, 1996) |
| " Nine patients had symptoms resembling myocardial ischemia, one patient died due to assumed myocardial infarction related closely to fluorouracil treatment, four patients had supraventricular arrhythmia, and one patient had congestive heart failure." | 3.68 | Cardiotoxicity of 5-fluorouracil in combination with folinic acid in patients with gastrointestinal cancer. ( Bokemeyer, C; Harstrick, A; Hiddemann, W; Köhne-Wömpner, CH; Mügge, A; Papageorgiou, E; Poliwoda, H; Schöber, C; Stahl, M; Wilke, H, 1993) |
| "Three cases of cardiotoxicity manifested by chest pain, tachycardia, respiratory distress, and electrocardiographic changes simulating acute myocardial infarction or ischemia were observed during the course of combination chemotherapy with etoposide, cisplatin, and continuous infusion of 5-fluorouracil in patients with advanced non-small cell lung cancer." | 3.68 | Electrocardiographic changes simulating acute myocardial infarction or ischemia associated with combination chemotherapy with etoposide, cisplatin, and 5-fluorouracil. ( Kim, SH; Lee, JS; Lee, KH, 1990) |
| "Acute myocardial infarction was observed in two patients receiving standard intravenous doses of 5-fluorouracil (5-FU)-based chemotherapy." | 3.68 | Thrombogenicity of intravenous 5-fluorouracil alone or in combination with cisplatin. ( Esparaz, B; Green, D; Kies, M; Kuzel, T, 1990) |
| "The authors describe the first case of myocardial infarction in their department which occurred during 5-fluorouracil treatment." | 3.67 | [The development of myocardial infarct in a patient treated with 5-fluorouracil]. ( Bulas, J; Cerná, M; Danko, J; Kasper, J; Murín, J; Uhliar, R, 1989) |
| "We report a case of advanced rectal cancer with bladder carcinoma." | 1.39 | [A case of advanced rectal cancer with bladder carcinoma salvaged from myocardial infarction during operation, showing tumor regression by XELOX treatment, good quality of life]. ( Kodama, M; Mekata, E; Okumura, K; Shiogai, Y; Tani, S; Tani, T, 2013) |
| "Capecitabine is an orally available chemotherapeutic agent that is converted to 5-fluorouracil (5-FU) after absorbtion." | 1.38 | Acute myocardial infarction after capecitabine treatment: not always vasospasm is responsible. ( Celiker, E; Eren, M; Güvenç, TS; Ilhan, E; Ozcan, KS, 2012) |
| "Capecitabine is a chemotherapeutic prodrug that is metabolised to 5-fluorouracil." | 1.35 | Coronary spasm induced by capecitabine mimicks ST elevation myocardial infarction. ( Curzen, NP; Ferchow, L; Hobson, A; Scott, PA, 2008) |
| " Five cardiopulmonary toxic events of Grade 3 or greater were observed in 4 patients, Grade 5 heart failure and Grade 3 pericarditis in 1 patient, and Grade 3 myocardial infarction, Grade 3 radiation pneumonitis, and Grade 3 pleural effusion." | 1.35 | Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma. ( Chin, K; Gomi, K; Ito, H; Kozuka, T; Matsuura, M; Morota, M; Oguchi, M; Yamashita, T, 2009) |
| " Coronary spasm is the most commonly suspected hypothesis, but further studies are warranted to seek for toxic inflammatory lesions of the myocardium (apoptosis, necrosis, fibrosis)." | 1.33 | Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease. ( Barel, C; Belkhiria, M; Bui-Xuan, B; Descotes, J; Lombard-Bohas, C; Tabib, A; Timour, Q; Tsibiribi, P, 2006) |
| "5-Fluorouracil (5-FU) is a chemotherapeutic agent which has been used to treat many solid tumors including cancers of the breast, ovary, cervix, bladder, prostate gland and gastrointestinal tract." | 1.29 | Cardiotoxicity related to 5-fluorouracil chemotherapy: a report of two cases. ( Chao, TY; Wang, WB; Weng, MC, 1995) |
| "5-Fluorouracil is widely known to be toxic to the hematopoietic and gastrointestinal systems." | 1.29 | Clinical cardiotoxicity of 5-fluorouracil. ( Keefe, DL; Pierri, MK; Roistacher, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (18.37) | 18.7374 |
| 1990's | 18 (36.73) | 18.2507 |
| 2000's | 12 (24.49) | 29.6817 |
| 2010's | 10 (20.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, SP | 1 |
| Tam, M | 1 |
| Vega, RM | 1 |
| Perez, CA | 1 |
| Gerber, NK | 1 |
| Zhang, D | 1 |
| Ma, J | 1 |
| Rateesh, S | 1 |
| Luis, SA | 1 |
| Luis, CR | 1 |
| Hughes, B | 1 |
| Nicolae, M | 1 |
| Scott, PA | 1 |
| Ferchow, L | 1 |
| Hobson, A | 1 |
| Curzen, NP | 1 |
| Morota, M | 1 |
| Gomi, K | 1 |
| Kozuka, T | 1 |
| Chin, K | 1 |
| Matsuura, M | 1 |
| Oguchi, M | 1 |
| Ito, H | 1 |
| Yamashita, T | 1 |
| Karabay, CY | 1 |
| Gecmen, C | 1 |
| Aung, SM | 1 |
| Guler, A | 1 |
| Candan, O | 1 |
| Batgerel, U | 1 |
| Kalayci, A | 1 |
| Kirma, C | 1 |
| Killu, A | 1 |
| Madhavan, M | 1 |
| Prasad, K | 1 |
| Prasad, A | 1 |
| Güvenç, TS | 1 |
| Celiker, E | 1 |
| Ozcan, KS | 1 |
| Ilhan, E | 1 |
| Eren, M | 1 |
| Okines, AF | 1 |
| Langley, RE | 1 |
| Thompson, LC | 1 |
| Stenning, SP | 1 |
| Stevenson, L | 1 |
| Falk, S | 1 |
| Seymour, M | 1 |
| Coxon, F | 1 |
| Middleton, GW | 1 |
| Smith, D | 1 |
| Evans, L | 1 |
| Slater, S | 1 |
| Waters, J | 1 |
| Ford, D | 1 |
| Hall, M | 1 |
| Iveson, TJ | 1 |
| Petty, RD | 1 |
| Plummer, C | 1 |
| Allum, WH | 1 |
| Blazeby, JM | 1 |
| Griffin, M | 1 |
| Cunningham, D | 1 |
| Steger, F | 1 |
| Hautmann, MG | 1 |
| Kölbl, O | 1 |
| Ozturk, MA | 1 |
| Ozveren, O | 1 |
| Cinar, V | 1 |
| Erdik, B | 1 |
| Oyan, B | 1 |
| Okumura, K | 1 |
| Tani, S | 1 |
| Shiogai, Y | 1 |
| Kodama, M | 1 |
| Mekata, E | 1 |
| Tani, T | 1 |
| Erol, MK | 1 |
| Acikel, M | 1 |
| Senocak, H | 1 |
| Mafrici, A | 1 |
| Alberti, A | 1 |
| Corrada, E | 1 |
| Ferrari, S | 1 |
| Marenna, B | 1 |
| Leitman, M | 1 |
| Baram, S | 1 |
| Sidenko, S | 1 |
| Abo-Kishk, I | 1 |
| Peleg, E | 1 |
| Vered, Z | 1 |
| Gul, M | 1 |
| Duzenli, A | 1 |
| Bircan, M | 1 |
| Cander, B | 1 |
| Kocak, S | 1 |
| Ozdemir, K | 1 |
| Tsibiribi, P | 1 |
| Descotes, J | 1 |
| Lombard-Bohas, C | 1 |
| Barel, C | 1 |
| Bui-Xuan, B | 1 |
| Belkhiria, M | 1 |
| Tabib, A | 1 |
| Timour, Q | 1 |
| Lu, JI | 1 |
| Carhart, RL | 1 |
| Graziano, SL | 1 |
| Gajra, A | 1 |
| Gundling, F | 1 |
| Fuchs, M | 1 |
| Nowak, L | 1 |
| Antoni, D | 1 |
| Hoffmann, E | 1 |
| Schepp, W | 1 |
| Canale, ML | 1 |
| Camerini, A | 1 |
| Stroppa, S | 1 |
| Porta, RP | 1 |
| Caravelli, P | 1 |
| Mariani, M | 1 |
| Balbarini, A | 1 |
| Ricci, S | 1 |
| Misao, Y | 1 |
| Arai, M | 1 |
| Ohno, T | 1 |
| Ushikoshi, H | 1 |
| Onogi, H | 1 |
| Kobayashi, H | 1 |
| Takemura, G | 1 |
| Minatoguchi, S | 1 |
| Fujiwara, T | 1 |
| Fujiwara, H | 1 |
| Sacks, H | 1 |
| Chalmers, TC | 1 |
| Smith, H | 1 |
| Labianca, R | 3 |
| Beretta, G | 1 |
| Clerici, M | 1 |
| Fraschini, P | 1 |
| Luporini, G | 2 |
| Mizuno, Y | 1 |
| Hokamura, Y | 1 |
| Kimura, T | 1 |
| Kimura, Y | 1 |
| Kaikita, K | 1 |
| Yasue, H | 1 |
| Weng, MC | 1 |
| Wang, WB | 1 |
| Chao, TY | 1 |
| Jameson, M | 1 |
| Thompson, P | 1 |
| Hastie, B | 1 |
| Unverdorben, M | 1 |
| Birkenhake, S | 1 |
| Kunkel, B | 1 |
| Dunst, J | 1 |
| Keefe, DL | 1 |
| Roistacher, N | 1 |
| Pierri, MK | 1 |
| Schöber, C | 1 |
| Papageorgiou, E | 1 |
| Harstrick, A | 1 |
| Bokemeyer, C | 1 |
| Mügge, A | 1 |
| Stahl, M | 1 |
| Wilke, H | 1 |
| Poliwoda, H | 1 |
| Hiddemann, W | 1 |
| Köhne-Wömpner, CH | 1 |
| Anderson, NR | 1 |
| Lokich, JJ | 1 |
| Moore, C | 1 |
| Maurer, U | 1 |
| Härle, M | 1 |
| Jungius, KP | 1 |
| Farooqi, IS | 1 |
| Aronson, JK | 1 |
| Pedersen, K | 1 |
| Mixon, R | 1 |
| Donovan, CT | 1 |
| McGlinchey, PG | 1 |
| Webb, ST | 1 |
| Campbell, NP | 1 |
| Villani, F | 1 |
| Guindani, A | 1 |
| Pagnoni, A | 1 |
| Tomomatsu, H | 1 |
| Morita, N | 1 |
| Nagai, T | 1 |
| Shiwaku, Y | 1 |
| Shingami, T | 1 |
| Miura, Y | 1 |
| Kihara, K | 1 |
| Nakao, Y | 1 |
| Shimokawahara, H | 1 |
| Hashimoto, S | 1 |
| Yunoki, K | 1 |
| Andrieu, J | 1 |
| Crenn, P | 1 |
| Schwob, J | 1 |
| Roussin-Bretagne, S | 1 |
| Jean, F | 1 |
| Zeymer, U | 1 |
| Neuhaus, KL | 1 |
| Fonte, CE | 1 |
| Cardello, F | 1 |
| Braumann, D | 1 |
| Mainzer, K | 1 |
| Günzl, C | 1 |
| Lewerenz, B | 1 |
| Lee, KH | 1 |
| Lee, JS | 1 |
| Kim, SH | 1 |
| Höring, E | 1 |
| Neef, B | 1 |
| von Gaisberg, U | 1 |
| Kuzel, T | 1 |
| Esparaz, B | 1 |
| Green, D | 1 |
| Kies, M | 1 |
| Cierlińska, M | 1 |
| Kostecka-Pokryszko, A | 1 |
| Kuźnicki, J | 1 |
| Czajkowska, R | 1 |
| Murín, J | 1 |
| Kasper, J | 1 |
| Danko, J | 1 |
| Cerná, M | 1 |
| Bulas, J | 1 |
| Uhliar, R | 1 |
| Ensley, JF | 1 |
| Patel, B | 1 |
| Kloner, R | 1 |
| Kish, JA | 1 |
| Wynne, J | 1 |
| al-Sarraf, M | 1 |
| Segalini, G | 1 |
| Beretta, GD | 1 |
| Borsotti, E | 1 |
| Calasso, F | 1 |
| Carini, L | 1 |
| De Ceglia, S | 1 |
| Rocca, A | 1 |
| Leone, B | 1 |
| Rabinovich, M | 1 |
| Ferrari, CR | 1 |
| Boyer, J | 1 |
| Rosso, H | 1 |
| Strauss, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Individual Radiosensitivity of Cancer Patients to be Treated by Radiotherapy or Radiochemotherapy Per-operative[NCT02797405] | 97 participants (Actual) | Interventional | 2016-10-31 | Terminated (stopped due to Withdrawal of analysis study Partner.) | |||
| A Randomised Phase II/III Trial of Peri-Operative Chemotherapy With or Without Bevacizumab in Operable Oesophagogastric Adenocarcinoma and A Feasibility Study Evaluating Lapatinib in HER-2 Positive Oesophagogastric Adenocarcinomas and (in Selected Centres[NCT00450203] | Phase 2/Phase 3 | 1,103 participants (Anticipated) | Interventional | 2007-10-31 | Recruiting | ||
| Apatinib Plus XELOX Regime as Neoadjuvant Therapy in Locally Advanced Gastric Cancer Patients With Lymph Node Metastasis[NCT03229096] | Phase 2 | 35 participants (Anticipated) | Interventional | 2017-02-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluorouracil and Myocardial Infarction
| Article | Year |
|---|---|
Takotsubo syndrome: an underdiagnosed complication of 5-fluorouracil mimicking acute myocardial infarction.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemoth | 2013 |
5-Fuorouracil cardiotoxicity.
Topics: Adult; Aged; Angina Pectoris; Electrocardiography; Female; Fluorouracil; Heart; Humans; Male; Middle | 1979 |
[Cardiotoxicity of 5-fluorouracil. Personal cases and review of the literature].
Topics: Aged; Angina Pectoris; Female; Fluorouracil; Heart; Humans; Male; Myocardial Infarction | 1987 |
2 trials available for fluorouracil and Myocardial Infarction
| Article | Year |
|---|---|
Effect of Breast Irradiation on Cardiac Disease in Women Enrolled in BCIRG-001 at 10-Year Follow-Up.
Topics: Adult; Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Card | 2017 |
Bevacizumab with peri-operative epirubicin, cisplatin and capecitabine (ECX) in localised gastro-oesophageal adenocarcinoma: a safety report.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc | 2013 |
Bevacizumab with peri-operative epirubicin, cisplatin and capecitabine (ECX) in localised gastro-oesophageal adenocarcinoma: a safety report.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc | 2013 |
Bevacizumab with peri-operative epirubicin, cisplatin and capecitabine (ECX) in localised gastro-oesophageal adenocarcinoma: a safety report.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc | 2013 |
Bevacizumab with peri-operative epirubicin, cisplatin and capecitabine (ECX) in localised gastro-oesophageal adenocarcinoma: a safety report.
Topics: Adenocarcinoma; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protoc | 2013 |
44 other studies available for fluorouracil and Myocardial Infarction
| Article | Year |
|---|---|
Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil.
Topics: Animals; Fluorouracil; Heart; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondria, H | 2018 |
Myocardial infarction secondary to 5-fluorouracil: not an absolute contraindication to rechallenge?
Topics: Adult; Antineoplastic Agents; Drug Administration Schedule; Fluorouracil; Humans; Male; Myocardial I | 2014 |
Coronary spasm induced by capecitabine mimicks ST elevation myocardial infarction.
Topics: Aged; Antimetabolites, Antineoplastic; Capecitabine; Chest Pain; Colorectal Neoplasms; Coronary Vaso | 2008 |
Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squ | 2009 |
Is 5-fluorouracil-induced vasospasm a Kounis syndrome? A diagnostic challenge.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Signet Ring Cell; Coronary Vasospasm; Electrocardiograph | 2011 |
5-fluorouracil induced pericarditis.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Diagnosis, Differential; Fluorouracil; Humans; M | 2011 |
Acute myocardial infarction after capecitabine treatment: not always vasospasm is responsible.
Topics: Capecitabine; Coronary Thrombosis; Coronary Vasospasm; Deoxycytidine; Female; Fluorouracil; Humans; | 2012 |
5-FU-induced cardiac toxicity--an underestimated problem in radiooncology?
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma; Cardiotoxins; Chemoradiotherapy; Electrocardiograp | 2012 |
[A case of advanced rectal cancer with bladder carcinoma salvaged from myocardial infarction during operation, showing tumor regression by XELOX treatment, good quality of life].
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluo | 2013 |
Non-Q-Wave acute anterior myocardial infarction associated with 5-fluorouracil and cisplatin chemotherapy.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; F | 2003 |
Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antimetabolites, Antineoplas | 2003 |
Transient left ventricular and right atrial thrombosis after 5-fluorouracil therapy.
Topics: Abdominal Neoplasms; Adolescent; Carcinoma, Signet Ring Cell; Echocardiography; Fluorouracil; Heart | 2004 |
Cardiotoxicity resembling myocardial infarction that occurs during chemotherapy with 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Chest Pain; Colonic Neoplasms; Diagnosis, Differential; Electrocardiography; | 2005 |
Cardiotoxicity of 5-fluorouracil in 1350 patients with no prior history of heart disease.
Topics: Adult; Aged; Angina Pectoris; Antimetabolites, Antineoplastic; Cardiac Output, Low; Chest Pain; Fema | 2006 |
Acute coronary syndrome secondary to fluorouracil infusion.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplas | 2006 |
["Iatrogenic acute coronary syndrome"--59 year old patient with adenocarcinoma of ascending colon and stenocardia while receiving adjuvant chemotherapy with 5-fluorouracil].
Topics: Adenocarcinoma; Angina Pectoris; Chemotherapy, Adjuvant; Colon, Ascending; Colonic Neoplasms; Fluoro | 2006 |
A case of acute myocardial infarction during 5-fluorouracil infusion.
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Coronary Angiography; Creatine Kinase, MB For | 2006 |
Modification of post-myocardial infarction granulocyte-colony stimulating factor therapy with myelo-suppressives.
Topics: Animals; Apoptosis; Benzylamines; Blood Cell Count; Chemokine CXCL12; Chemokines, CXC; Cyclams; Cycl | 2007 |
Randomized versus historical controls for clinical trials.
Topics: Abortion, Habitual; Anticoagulants; BCG Vaccine; Clinical Trials as Topic; Colonic Neoplasms; Corona | 1982 |
Cardiac toxicity of 5-fluorouracil: a study on 1083 patients.
Topics: Aged; Angina Pectoris; Drug Therapy, Combination; Female; Fluorouracil; Heart; Humans; Male; Middle | 1982 |
A case of 5-fluorouracil cardiotoxicity simulating acute myocardial infarction.
Topics: Aged; Breast Neoplasms; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diagnosis, Differentia | 1995 |
Cardiotoxicity related to 5-fluorouracil chemotherapy: a report of two cases.
Topics: Aged; Female; Fluorouracil; Humans; Male; Middle Aged; Myocardial Infarction; Nasopharyngeal Neoplas | 1995 |
5 Fluorouracil cardiotoxicity.
Topics: Adult; Fluorouracil; Heart; Humans; Male; Myocardial Infarction | 1995 |
[Extended reversible global left ventricular contraction dysfunction with symptomless coronary system as effect of cytostatic therapy with 5-fluorouracil].
Topics: Anus Neoplasms; Combined Modality Therapy; Coronary Angiography; Coronary Vasospasm; Diagnosis, Diff | 1994 |
Clinical cardiotoxicity of 5-fluorouracil.
Topics: Aged; Arrhythmias, Cardiac; Coronary Vasospasm; Electrocardiography; Female; Fluorouracil; Heart Arr | 1993 |
Cardiotoxicity of 5-fluorouracil in combination with folinic acid in patients with gastrointestinal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arrhythmias, Cardiac; Coronary Disease; | 1993 |
The syndrome of 5-fluorouracil cardiotoxicity: an elusive cardiopathy.
Topics: Angina Pectoris; Fluorouracil; Heart Diseases; Humans; Myocardial Infarction | 1993 |
[5-fluorouracil: cause of a fatal myocardial infarction in combined radiochemotherapy?].
Topics: Adenocarcinoma; Adrenal Gland Neoplasms; Antimetabolites, Antineoplastic; Fatal Outcome; Female; Flu | 1996 |
Iatrogenic chest pain: a case of 5-fluorouracil cardiotoxicity.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Chest Pain; Fluorouracil; Humans; Male; Myocar | 1996 |
Nurses develop a care standard for 5-fluorouracil-associated cardiotoxicity.
Topics: Aged; Antimetabolites, Antineoplastic; Fluorouracil; Humans; Male; Myocardial Infarction; Oncology N | 1997 |
5-fluorouracil-induced cardiotoxicity mimicking myocardial infarction: a case report.
Topics: Aged; Antimetabolites, Antineoplastic; Chest Pain; Coronary Angiography; Coronary Vasospasm; Diagnos | 2001 |
[A case with gastric cancer by OK-MF'C therapy (author's transl)].
Topics: Adenocarcinoma; Antineoplastic Agents; Cytarabine; Drug Therapy, Combination; Fluorouracil; Humans; | 1979 |
[Myocardial damage after use of 5 fluorouracil in digestive pathology].
Topics: Aged; Fluorouracil; Humans; Male; Myocardial Infarction; Rectal Neoplasms | 1991 |
5-fluorouracil cardiotoxicity: the risk of rechallenge.
Topics: Angina Pectoris; Coronary Vasospasm; Fluorouracil; Humans; Myocardial Infarction; Recurrence | 1991 |
[The cardiotoxic side effects of 5-fluorouracil].
Topics: Angina Pectoris; Electrocardiography; Fluorouracil; Heart; Humans; Male; Middle Aged; Myocardial Inf | 1991 |
Chest pain in a cancer patient on chemotherapy.
Topics: Adenocarcinoma; Adult; Colonic Neoplasms; Fluorouracil; Humans; Male; Myocardial Infarction; Strepto | 1991 |
[Myocardial infarcts within the scope of 5-fluorouracil therapy].
Topics: Adenocarcinoma; Adult; Electrocardiography; Fluorouracil; Humans; Infusions, Intravenous; Liver Neop | 1990 |
Electrocardiographic changes simulating acute myocardial infarction or ischemia associated with combination chemotherapy with etoposide, cisplatin, and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Coronary Disease; Diagnosis, | 1990 |
Intramural myocardial infarction under combined radiochemotherapy of an oesophageal carcinoma.
Topics: Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Esophageal Neoplasms; Fluorouracil; | 1990 |
Thrombogenicity of intravenous 5-fluorouracil alone or in combination with cisplatin.
Topics: Adult; Aged; Anus Neoplasms; Carcinoma, Squamous Cell; Cisplatin; Fibrinogen; Fibrinopeptide A; Fluo | 1990 |
[Threatened myocardial infarction during the treatment with 5-fluorouracil].
Topics: Cecal Neoplasms; Fluorouracil; Humans; Male; Middle Aged; Myocardial Infarction; Palliative Care | 1987 |
[The development of myocardial infarct in a patient treated with 5-fluorouracil].
Topics: Adult; Electrocardiography; Fluorouracil; Humans; Lip Neoplasms; Male; Myocardial Infarction | 1989 |
The clinical syndrome of 5-fluorouracil cardiotoxicity.
Topics: Adult; Aged; Coronary Disease; Death, Sudden; Electrocardiography; Female; Fluorouracil; Heart Disea | 1989 |
Cardiotoxicity as a result of 5-fluorouracil therapy.
Topics: Adenocarcinoma; Adult; Fluorouracil; Heart; Humans; Male; Myocardial Infarction; Sigmoid Neoplasms; | 1985 |