Page last updated: 2024-10-27

fluorouracil and Myelopathy

fluorouracil has been researched along with Myelopathy in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy."5.33Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005)
"This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy."1.33Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paralta Branco, F1
Brito, CB1
Luz, G1
Teixeira, JA1
Chan, L1
Yeo, W1
Leung, SF1
Griffith, J1
Ng, EK1
Chan, AT1
Barstis, JL1
Black, AC1
Sun, Y1
Wang, LX1
Wang, L1
Sun, SX1
Cao, XJ1
Wang, P1
Feng, L1

Other Studies

4 other studies available for fluorouracil and Myelopathy

ArticleYear
Central venous catheter misplaced in the epidural space.
    BMJ case reports, 2019, Apr-08, Volume: 12, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Catheterization, Central Venous; Centra

2019
Delayed radiation myelopathy after concurrent chemoradiation for hypopharyngeal-esophageal carcinoma.
    Acta oncologica (Stockholm, Sweden), 2005, Volume: 44, Issue:2

    Topics: Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Degluti

2005
Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine.
    Cancer investigation, 2005, Volume: 23, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2005
A comparison of the effectiveness of mitomycin C and 5-fluorouracil in the prevention of peridural adhesion after laminectomy.
    Journal of neurosurgery. Spine, 2007, Volume: 7, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Dura Mater; Fluorouracil; Laminectomy; Lumbar Vertebrae; M

2007