fluorouracil has been researched along with Myelomonocytic Leukemia, Chronic in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, ZJ | 1 |
| Zhao, X | 1 |
| Banaszak, LG | 1 |
| Gutierrez-Rodrigues, F | 1 |
| Keyvanfar, K | 1 |
| Gao, SG | 1 |
| Quinones Raffo, D | 1 |
| Kajigaya, S | 1 |
| Young, NS | 1 |
1 other study available for fluorouracil and Myelomonocytic Leukemia, Chronic
| Article | Year |
|---|---|
CRISPR/Cas9-mediated ASXL1 mutations in U937 cells disrupt myeloid differentiation.
Topics: Cell Cycle; Cell Differentiation; Cell Proliferation; CRISPR-Cas Systems; Fluorouracil; Humans; Leuk | 2018 |