Page last updated: 2024-10-27

fluorouracil and Muscle Contraction

fluorouracil has been researched along with Muscle Contraction in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sung, EZ1
Arasaradnam, RP1
Jarvie, EM1
James, S1
Goodyear, SJ1
Borman, RA1
Snead, D1
Sanger, GJ1
Nwokolo, CU1
Theisen, J1
Kauer, WK1
Nekarda, H1
Schmid, L1
Stein, HJ1
Siewert, JR1
Blunt, RJ2
Jones, R2
Vrbová, G1

Other Studies

4 other studies available for fluorouracil and Muscle Contraction

ArticleYear
Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function.
    Molecular biology reports, 2012, Volume: 39, Issue:12

    Topics: Acetylcholinesterase; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecita

2012
Neoadjuvant radiochemotherapy for patients with locally advanced rectal cancer leads to impairment of the anal sphincter.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Antineoplastic Agents;

2006
Inhibition of cell division and the development of denervation hypersensitivity in skeletal muscle.
    Pflugers Archiv : European journal of physiology, 1975, Mar-26, Volume: 355, Issue:3

    Topics: Acetylcholine; Animals; Autoradiography; Cell Division; Cell Nucleus; Dactinomycin; Fluorouracil; Hi

1975
Inhibition of cell dcivision and denervation hypersensitivity in skeletal muscle.
    The Journal of physiology, 1972, Volume: 226, Issue:2

    Topics: Acetylcholine; Animals; Fluorouracil; Hindlimb; Methotrexate; Mitosis; Muscle Contraction; Muscle De

1972