fluorouracil has been researched along with Mouth Neoplasms in 302 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study aimed to evaluate efficacy and adverse effects of Nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in the treatment of advanced oral carcinoma." | 9.19 | Efficacy of nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in treatment of advanced oral carcinoma. ( Gu, QP; Guo, W; Li, ZP; Meng, J; Meng, QF; Si, YM; Zhang, J; Zhuang, QW, 2014) |
| "Stomatitis caused by a combined chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP) is a serious problem in the course of treatment for patients with oral carcinoma." | 9.08 | [Inhibition of 5-fluorouracil-cisplatin-induced stomatitis by oral cryotherapy: use of an ice-bar containing fibrinolysin and deoxyribonuclease combine (Elase)]. ( Kumagai, S; Mori, S; Morikawa, H; Sakaki, K; Sato, A; Song, ST, 1997) |
| "The present study aimed to evaluate efficacy and adverse effects of Nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in the treatment of advanced oral carcinoma." | 5.19 | Efficacy of nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in treatment of advanced oral carcinoma. ( Gu, QP; Guo, W; Li, ZP; Meng, J; Meng, QF; Si, YM; Zhang, J; Zhuang, QW, 2014) |
| "Stomatitis caused by a combined chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP) is a serious problem in the course of treatment for patients with oral carcinoma." | 5.08 | [Inhibition of 5-fluorouracil-cisplatin-induced stomatitis by oral cryotherapy: use of an ice-bar containing fibrinolysin and deoxyribonuclease combine (Elase)]. ( Kumagai, S; Mori, S; Morikawa, H; Sakaki, K; Sato, A; Song, ST, 1997) |
| "The time for the neutrophil count to recover after subcutaneous injection of filgrastim BS1 or lenograstim was studied in patients suffering from neutropenia following preoperative combined chemotherapy using docetaxel, nedaplatin, or cisplatin (in divided doses for 5 days)and 5-fluorouracil for oral cancer." | 3.81 | [Clinical Investigation of the Effects of Filgrastim BS1 on Neutropenia Following Oral Cancer Chemotherapy (TPF Therapy)]. ( Iwasaki, K; Mitomo, K; Nakayama, S; Tamate, S; Uchiyama, K; Yamada, M, 2015) |
| "Oropharyngeal cancers were most responsive, whereas results were less satisfactory for oral cancers." | 3.76 | Short-term results of the combination of cis-platinum, 5-fluorouracil and bleomycin in advanced upper aerodigestive tract cancers. ( Bassot, V; Brasnu, D; Jacquillat, C; Lacau St Guily, J; Laccourreye, H; Weil, M, 1986) |
| "We examined the mechanisms underlying the enhancement of radiosensitivity and chemosensitivity to gamma-irradiation (IR) and 5-Fluorouracil (5-FU) in human oral carcinoma cells (B88) in which NF-kappaB activity was constitutively suppressed." | 3.72 | Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8. ( Ashida, Y; Azuma, M; Harada, K; Kawaguchi, S; Motegi, K; Sato, M; Takashima, R; Tamatani, T, 2004) |
| "An allergic reaction consisting of angioneurotic edema secondary to continuous infusion 5-fluorouracil occurred in a patient with recurrent carcinoma of the oral cavity, cirrhosis, and cisplatin-induced impaired renal function." | 3.67 | Allergic reaction to 5-fluorouracil infusion. ( Sridhar, KS, 1986) |
| "15 patients with superficial basaliomas or premalignant epithelial neoplastic disorders (actinic keratosis, leukoplakia, Bowen's disease) were treated locally over three weeks with retinoic acid (RA) alone or in combination with 5-fluorouracil (5-FU)." | 3.66 | [Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil]. ( Kurka, M; Orfanos, CE; Pullmann, H, 1978) |
| "Our study demonstrates that hyperthermia combined with induction chemotherapy is associated with a high response rate and provides a new treatment option for patients with resectable stage III or IVA OSCC." | 3.01 | A multicenter randomized phase II trial of hyperthermia combined with TPF induction chemotherapy compared with TPF induction chemotherapy in locally advanced resectable oral squamous cell carcinoma. ( Chen, Y; Ge, M; Guo, W; He, Y; Ju, H; Ma, X; Meng, J; Qiu, W; Ren, G; Song, H; Wu, Y; Zhuang, Q, 2021) |
| "Inoperable oral cavity squamous cell carcinoma (SCC) is a highly invasive disease associated with the extensive destruction of locoregional tissues and a dismal prognosis." | 2.84 | Effectiveness of incorporating cetuximab into docetaxel/cisplatin/fluorouracil induction chemotherapy and chemoradiotherapy for inoperable squamous cell carcinoma of the oral cavity: A phase II study. ( Chang, PM; Chen, MH; Chu, PY; Lu, HJ; Tai, SK; Wang, LW; Yang, MH, 2017) |
| "5-Fluorouracil (5-FU) is a widely used drug for the therapy of cancer." | 2.84 | The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma. ( Chen, F; Chen, W; Feng, X; Luo, Q; Meng, G; Wang, H; Zhang, H, 2017) |
| "Twenty-nine patients of oral mucosa squamous cell carcinoma pathologically diagnosed between 2006 and 2012 were enrolled into this study." | 2.79 | [Grade IV myelosuppression after induction chemotherapy of TPF on oral cancer: clinical analysis of 29 cases]. ( Jin, J; Li, RX; Liu, SH; Wang, LP; Wang, Y; Ye, MC; Zhou, Y; Zhu, WZ; Zuo, Y, 2014) |
| "Outcome of the patients with oral cancer is poor." | 2.77 | Survival following non surgical treatments for oral cancer: a single institutional result. ( Larizadeh, MH; Shabani, M, 2012) |
| " This regimen is under way in which chemotherapy with 5-FU 500 mg/day on days 1 to 5 and superselective intra-arterial infusion of CDGP on day 6 combined with radiation therapy is being evaluated for locally advanced oral cancer." | 2.71 | [Clinical trial of chemotherapy by superselective intra-arterial infusion of nedaplatin combined with radiotherapy for advanced oral cancer]. ( Goto, M; Shikimori, M; Yamshita, Y, 2005) |
| "Eleven patients with oral cancer were treated with the new platinum agent, nedaplatin, and 5-fluorouracil and simultaneous radiation therapy." | 2.71 | Concurrent chemoradiotherapy with new platinum compound nedaplatin in oral cancer. ( Fukuda, K; Hanakita, T; Hayatsu, Y; Ita, M; Mitsuoka, K; Okafuji, M, 2003) |
| "122 patients with primary squamous cell carcinoma of the lip, the oral cavity and the oropharynx have been treated with 100 mg/m2 cisplatin bolus infusion and 120-h continuous infusion of 1000 mg/m2 5-fluorouracil following radical surgery; 99 patients completed all 3 cycles." | 2.71 | Postoperative chemotherapy with cisplatin and 5-fluorouracil in cancer of the oral cavity and the oropharynx--long-term results. ( Bitter, K; Ghahremani, MT; Kovács, AF; Stefenelli, U, 2003) |
| "Although the oral cancers in this study were extroverted superficial ulcerative cancers, and the number of patients was low at 8, this combined therapy is considered useful and worth evaluating in further accumulated cases." | 2.70 | [Evaluation of a combination chemotherapy with nedaplatin and 5-FU for oral cancers]. ( Iba, T; Ishida, Y; Nakata, T; Nishida, T; Ohtsuki, T; Shimada, T; Takigami, K; Tanaka, A; Tsuda, Y; Yamaguchi, Y; Yamamoto, G; Yoshitake, K, 2001) |
| "Sixty-five patients with advanced head and neck cancer underwent a definitive (53 patients) or a postoperative adjuvant (12 patients) chemoradiation treatment." | 2.70 | Accelerated hyperfractionated radiotherapy and concurrent protracted venous infusion chemotherapy in locally advanced head and neck cancer. ( Arcangeli, G; Arcangeli, S; Carlini, P; Cognetti, F; Danesi, DT; De Campora, E; Giovinazzo, G; Mecozzi, A; Saracino, B, 2002) |
| "The subjects were patients with squamous cell carcinoma of the oral cavity who had not received any therapy, comprising 7 patients with carcinoma of the tongue, 2 with buccal carcinoma, 2 with maxillary gingival carcinoma, and 1 with carcinoma of the oral floor." | 2.70 | [Combination chemotherapy with nedaplatin (CDGP) and 5-FU for oral cancer]. ( Ando, T; Fukada, K; Hoshino, M; Kuwazawa, T; Maruoka, Y; Nishihara, N; Ogiuchi, H; Ogiuchi, Y; Okamoto, T, 2002) |
| "All had squamous cell carcinomas of the oral cavity in stage III or in nonmetastatic stage IV and were selected for surgery or radiation therapy (if located in the tonsils or in the base of the tongue)." | 2.70 | Multidisciplinary approach in advanced cancer of the oral cavity: outcome with neoadjuvant chemotherapy according to intention-to-treat local therapy. A phase II study. ( Alós, L; Blanch, JL; Castro, V; Domingo, J; Estapé, J; Grau, JJ; Nadal, A; Verger, E, 2002) |
| "Patients with previously untreated squamous cell carcinoma of the oral cavity were eligible for this trial." | 2.69 | High rate of clinical complete response to weekly outpatient neoadjuvant chemotherapy in oral carcinoma patients using a new regimen of cisplatin, 5-fluorouracil, and bleomycin alternating with methotrexate and epirubicin. ( Hsu, CY; Jan, JS; Lin, JC; Wong, DY, 1999) |
| "Retinol palmitate was administered at the dose of 15." | 2.67 | [5-fluorouracil, cisplatin and retinol palmitate in the management of advanced cancer of the oral cavity. Phase II study]. ( Di Matteo, G; Frati, L; Lelli, S; Rea, S; Recchia, F, 1993) |
| "Thirty-nine patients with previously untreated squamous cell carcinoma of the buccal mucosa were treated by two polychemotherapeutic regimens." | 2.65 | Polychemotherapy in squamous cell carcinoma of the buccal mucosa. ( Bannerjee, A; Dhawan, IK; Madan, NC; Sahoo, BK; Thakur, NS, 1983) |
| "Oral squamous cell carcinoma in situ has been described as a relatively rare lesion." | 2.38 | Management of oral squamous cell carcinoma in situ with topical 5-fluorouracil and laser surgery. ( Headington, JT; Maxson, BB; Scott, RF, 1989) |
| "The treatment of oral squamous cell carcinoma (OSCC) includes systemic chemotherapy and is associated with aggressive side effects on patients." | 1.91 | A novel intra-tumoral drug delivery carrier for treatment of oral squamous cell carcinoma. ( Aboushelib, MN; Al-Wakeel, E; Badawi, MF; Elsaady, SA, 2023) |
| "Among the different types of oral cancer, >90% of cases are oral squamous cell carcinoma (OSCC)." | 1.72 | Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin. ( Che, PC; Chen, JC; Chen, MS; Hsieh, MJ; Lee, IN; Wu, YP; Yang, KS, 2022) |
| "Oral cancer is one of the most common malignancies with an increased rate of incidence." | 1.72 | Transfersome Hydrogel Containing 5-Fluorouracil and Etodolac Combination for Synergistic Oral Cancer Treatment. ( Bollareddy, SR; Dasari, D; Dhar, A; Krishna, V; Roy, G; Venuganti, VVK, 2022) |
| "Ultrasound hyperthermic therapy combined with chemotherapy has a synergistic anti-tumor effect on patients with advanced oral squamous cell carcinoma, which is safe and effective, and is worthy of becoming another choice of tumor treatment." | 1.62 | [Analysis of curative effect of ultrasonic hyperthermia combined with TPF chemotherapy on 19 elderly with advanced oral squamous cell carcinoma]. ( Ge, LY; Gu, QP; Li, L; Li, XD; Li, ZP; Meng, J; Zhuang, QW, 2021) |
| "This study aims to characterize the pharmacokinetic (PK) profiles and identify important bioavailability barriers and pharmacological pathways of the key active components (KACs) of Antitumor B (ATB), a chemopreventive agent." | 1.62 | Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer. ( Bui, D; Duan, S; Hu, M; Singh, R; Wei, B; Wong, SJ; Yang, P; Yin, T; You, M, 2021) |
| "The objectives of this study were to evaluate survival in 141 patients with stage II-IV oral squamous cell carcinoma (OSCC) treated with preoperative intra-arterial chemotherapy with docetaxel, cisplatin, and peplomycin combined with intravenous chemotherapy using 5-fluorouracil (IADCPIVF) via the superficial temporal artery, and to clarify the prognostic factors." | 1.56 | Preoperative intra-arterial chemotherapy with docetaxel, cisplatin, and peplomycin combined with intravenous chemotherapy using 5-fluorouracil for oral squamous cell carcinoma. ( Endo, M; Hasegawa, H; Kaneko, T; Kanno, C; Kano, M; Kitabatake, T; Monma, T; Sato, E; Takeishi, E; Yamazaki, M, 2020) |
| "communis extract (JCo) on oral cancer and evaluated the synergistic effects of JCo combined with 5-fluorouracil (5-FU)." | 1.56 | Suppression of oral cancer by induction of cell cycle arrest and apoptosis using Juniperus communis extract. ( Chang, KF; Hsiao, CY; Hsieh, MC; Huang, XF; Lee, CC; Lee, MS; Lee, SC; Tsai, NM, 2020) |
| "Patients with oral squamous cell carcinoma were enrolled." | 1.48 | Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study. ( Ando, H; Fujimura, A; Hayasaka, JI; Jinbu, Y; Kusama, M; Mori, Y; Noguchi, T; Okada, N; Tsuchiya, Y; Ushijima, K, 2018) |
| "Ninety-seven patients with oral squamous cell carcinoma, treated preoperatively with radiotherapy in combination with chemotherapy or cetuximab, were included in this retrospective analysis." | 1.48 | P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC. ( Eder-Czembirek, C; Fuereder, T; Selzer, E; Sulzbacher, I, 2018) |
| "Human papillomavirus-associated oropharyngeal cancer was associated with a significant improved overall survival, locoregional, distant and overall tumor control rates in multivariate analysis." | 1.48 | Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer". ( Baumeister, P; Belka, C; Ganswindt, U; Hess, J; Kirchner, T; Macht, C; Maihoefer, C; Pflugradt, U; Schneider, L; Schüttrumpf, L; Walch, A; Woischke, C; Zitzelsberger, H, 2018) |
| "5-Fluorouracil (5-FU) is an essential chemotherapeutic agent for oral squamous cell carcinoma (OSCC)." | 1.46 | Synergistic effect of honokiol and 5-fluorouracil on apoptosis of oral squamous cell carcinoma cells. ( Chen, F; Chen, Q; Deng, P; Feng, M; Ji, N; Jiang, L; Li, J; Li, L; Liao, G; Lin, Y; Liu, J; Xu, H; Zeng, X, 2017) |
| "The FBXW7 expression patterns in oral squamous cell carcinoma and adjacent normal tissues from 15 patients who underwent radical resection were evaluated using quantitative real-time polymerase chain reaction and immunohistochemical staining." | 1.46 | FBXW7 expression affects the response to chemoradiotherapy and overall survival among patients with oral squamous cell carcinoma: A single-center retrospective study. ( Arita, H; Hiraki, A; Hirosue, A; Kawahara, K; Kojima, T; Matsuoka, Y; Murakami, R; Nagata, M; Nakashima, H; Nakayama, H; Sakata, J; Shinohara, M; Toya, R; Yoshida, R, 2017) |
| "Metformin was reported to be effective against various cancers as it inhibits cell proliferation by activating AMPK, and inhibiting mTOR and HIF-1α." | 1.43 | Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma. ( Ferdous, T; Harada, K; Harada, T; Ueyama, Y, 2016) |
| "Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia." | 1.43 | Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline. ( Chang, YC; Chou, MY; Lee, SS; Peng, CY; Wang, TY; Yu, CC, 2016) |
| "A total of ninety cases with oral cancer were recruited in this study." | 1.43 | Evaluating the efficacy and safety of continuous arterial infusion chemotherapy with cisplatin and 5-fluorouracil in treating oral cancer. ( Li, X; Liu, W; Tao, H; Yan, J; Ye, M, 2016) |
| " As a systemic adverse event, neutropenia was significantly milder in GroupA than in GroupB (p=0." | 1.42 | [The Safety of Super-Selective Intra-Arterial Infusion Chemotherapy for Induction with Docetaxel, Cisplatin, and 5-Fluorouracil for Oral Cancer]. ( Hiraiwa, T; Koike, M; Okada, H; Senda, N; Suzuki, K, 2015) |
| "The treatment of head and neck squamous cell carcinoma (HNSCC) with N3 (>6cm) lymph nodes remains difficult, and the best treatment strategy has not been elucidated." | 1.42 | Role of induction chemotherapy for N3 head and neck squamous cell carcinoma. ( Hanai, N; Hasegawa, Y; Hirakawa, H; Nakashima, T; Nishikawa, D; Ozawa, T; Suzuki, H, 2015) |
| "In mouse xenograft model of oral squamous cell carcinoma (OSCC), SNNP loaded with 5-fluoro-uracile (5-FU-SNNP) remarkably retarded the tumor growth compared with free 5-FU, albeit SNNP alone showed no antitumor effect." | 1.42 | Self-Assembling Monomeric Nucleoside Molecular Nanoparticles Loaded with 5-FU Enhancing Therapeutic Efficacy against Oral Cancer. ( Chen, F; Chen, Q; Chu, L; Dan, H; Feng, H; He, Y; Ji, N; Jiang, L; Ju, X; Li, J; Li, L; Liang, X; Liu, D; Liu, J; Luo, X; Meng, J; Sun, C; Yang, H; Zeng, X; Zhao, H; Zhou, M; Zhou, Y, 2015) |
| "Oral squamous cell carcinoma (OSCC) comprises a subset of head and neck squamous cell carcinoma (HNSCC) with poor therapeutic outcomes and high glycolytic dependency." | 1.42 | Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma. ( Ding, X; Geng, M; Huang, M; Li, H; Sun, W; Wu, H; Xie, Z; Zhang, X, 2015) |
| "5-Fluorouracil (5-FU) has been used for oral squamous cell carcinoma (OSCC) treatments, and the acquisition of resistance is the major problem to successful OSCC treatment." | 1.40 | Establishment of 5-fluorouracil-resistant oral squamous cell carcinoma cell lines with epithelial to mesenchymal transition changes. ( Ferdous, T; Harada, K; Ueyama, Y, 2014) |
| "Oral squamous cell carcinoma specimens were obtained from 61 patients who underwent surgery following 5-fluorouracil-based chemoradiotherapy at Kumamoto University Hospital between October 2003 and January 2009." | 1.40 | A low Dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma. ( Hiraki, A; Hirosue, A; Kawahara, K; Kojima, T; Matsuoka, Y; Nagata, M; Nakagawa, Y; Nakayama, H; Shinohara, M; Takamune, Y; Tanaka, T; Yoshida, R; Yoshitake, Y, 2014) |
| "Eighty-one patients with oral squamous cell carcinoma (OSCC) received oral fluoropyrimidine UFT and radiotherapy (RT) with or without an immunotherapeutic agent OK-432." | 1.39 | Immunochemoradiotherapy for patients with oral squamous cell carcinoma: augmentation of OK-432-induced helper T cell 1 response by 5-FU and X-ray irradiation. ( Bando, T; Fujita, T; Goda, H; Hamakawa, H; Homma, S; Kan, S; Kawakami, Y; Koido, S; Nakashiro, K; Okamoto, M; Sato, M; Shimodaira, S; Tano, T; Yamashita, N, 2013) |
| "Oral squamous cell carcinoma (OSCC) is a common malignant tumor of the head and neck, and recurrence is an important prognostic factor in patients with OSCC." | 1.39 | The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases. ( Wang, B; Wang, XD; Yue, K; Zhang, S, 2013) |
| "Concurrent radiochemotherapy of oral squamous cell carcinoma was shown to drive the composition of inflammatory cells in a direction which is supposed to be prognostically favourable." | 1.38 | Radiochemotherapy induces a favourable tumour infiltrating inflammatory cell profile in head and neck cancer. ( Büttner, M; Distel, LV; Fietkau, R; Grabenbauer, GG; Lubgan, D; Nkenke, E; Tabachnyk, M, 2012) |
| "Oral squamous cell carcinoma (OSCC) is responsible for about 90% of oral malignancies and its incidence is increasing." | 1.38 | The effects of 5-fluorouracil alone and in combination with 13-cis retinoic acid and vitamin D3 on human oral squamous cell carcinoma lines. ( Dalirsani, Z; Farajnia, S; Javadzadeh, Y; Koozegari, S; Mehdipour, M, 2012) |
| "Honokiol (HNK) is a small organic molecule purified from magnolia species and has demonstrated anticancer activities in a variety of cancer cell lines; however, its effect on oral squamous cell carcinoma (OSCC) cells is unknown." | 1.37 | Honokiol: a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells. ( Chen, XR; Dan, HX; Ji, N; Li, XY; Liao, G; Lu, R; Zhou, M, 2011) |
| "However, oral squamous carcinoma cells (OSCCs) are resistant to these drugs, so finding a way to enhance the sensitivity of these cells to anticancer drugs is important." | 1.37 | The bacterial protein azurin enhances sensitivity of oral squamous carcinoma cells to anticancer drugs. ( Cho, JH; Cho, YJ; Kim, GC; Kim, S; Lee, MH; Park, BS, 2011) |
| " In this study, the response of human OSCC cells to Lentinan alone and in combination with S-1 was examined using nude mouse xenograft models." | 1.36 | Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo. ( Harada, K; Itashiki, Y; Takenawa, T; Ueyama, Y, 2010) |
| "Six patients with advanced oral squamous cell carcinoma were treated with preoperative concurrent chemoradiotherapy." | 1.35 | [Clinical effects of concurrent chemoradiotherapy (hyperfractionation and cisplatin/5-fluorouracil) for patients with advanced oral squamous cell carcinoma]. ( Hoshi, K; Ito, H; Jinbu, Y; Kusama, M; Matsumoto, K; Matsumura, T; Noguchi, T; Osano, H; Tsuchiya, Y, 2009) |
| "However, few studies examining oral squamous cell carcinomas (OSCCs) have been reported." | 1.35 | Combined evaluation of dihydropyrimidine dehydrogenase and thymidine phosphorylate mRNA levels in tumor predicts the histopathological effect of 5-fluorouracil-based chemoradiotherapy. ( Morishita, K; Ohno, S; Tateishi, Y; Tatemoto, Y; Ueta, E; Yamamoto, T, 2009) |
| " The pharmacokinetic parameters of 5-FU/PEG-PBLG nanoparticles in rabbit plasma were determined by measuring the 5-FUby high-performance liquid chromatography (HPLC)." | 1.35 | Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles. ( Guan, Z; Jiang, W; Li, S; Wang, A, 2008) |
| "Adenocarcinoma ex pleomorphic adenoma is a rare tumor, and thus the management of the tumor has not been established." | 1.33 | Adenocarcinoma ex pleomorphic adenoma of the head and neck: Report of five cases. ( Akagi, H; Kariya, S; Kosaka, M; Nishizaki, K; Orita, Y, 2006) |
| "In this study, three human oral cancer cell lines (SAS, HSC-4 and Ca9-22), a human breast cancer cell line MCF-7, and a normal human fibroblast cell line NHDF were tested." | 1.33 | Silencing of the p53R2 gene by RNA interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells. ( Baba, N; Iwamoto, T; Kawasaki, G; Mizuno, A; Yanamoto, S; Yoshitomi, I, 2005) |
| "We treated oral cancer using a targeting intra-arterial infusion chemotherapy with CDGP (nedaplatin); dosages were determined by the original formula." | 1.32 | [Clinical study of the area under the blood concentration-time curve of targeting intra-arterial infusion chemotherapy with nedaplatin for primary oral cancer]. ( Iwasaki, A; Miyake, M; Nagahata, S; Ogawa, T; Ohbayashi, Y; Ohkawa, M; Toyama, Y, 2004) |
| "The treatment of oral cancer has a strong impact on the quality of life." | 1.32 | [Evaluation of quality of life of patients with oral squamous cell carcinoma. Comparison of two treatment protocols in a prospective study-first results]. ( Bloch-Birkholz, A; Grabenbauer, G; Kessler, P; Leher, A; Neukam, FW; Wiltfang, J, 2003) |
| "The similarities to human oral cancer suggest that the model will be very useful in the evaluation of experimental therapies for oral cancer." | 1.32 | Clinical and pathological features of the murine AT-84 orthotopic model of oral cancer. ( Hutchison, R; Kellman, RM; Lou, E; Shillitoe, EJ, 2003) |
| "In vitro 5-FU treatment of oral cancer cells resulted in an increase in G1/S phase cells." | 1.32 | Effect of 5-fluorouracil on G1 phase cell cycle regulation in oral cancer cell lines. ( Hatori, M; Ito, D; Iwase, M; Li, MH; Nagumo, M; Odani, T; Sanada, M, 2004) |
| "102 cases with oral squamous cell carcinoma(OSCC) were included in the study (63 males and 39 females, aged 22 to 67 years)." | 1.32 | [The clinical application and evaluation of combined chemotherapy in comprehensive treatment for oral squamous cell carcinoma]. ( Liao, C; Liu, S; Wang, D, 2003) |
| "We encountered a case of extensive squamous cell carcinoma ranging from the tongue to the mouth floor, in which chemotherapy using a combination of nedaplatin and 5-FU was effective." | 1.31 | [A case of large carcinoma of the tongue and mouth floor, in which chemotherapy using a combination of nedaplatin and 5-FU was effective]. ( Inoda, H; Nishida, T; Nishikawa, M; Shimada, T; Takigami, K; Tanaka, A; Tsuda, Y; Yamamoto, G; Yoshitake, K, 2002) |
| "Cultured oral cancer cells were exposed to an optimum dose of 20 mg/ml of 5FU." | 1.31 | 5-Fluorouracil-induced apoptosis in cultured oral cancer cells. ( Hu, D; Oda, D; Poot, M; Tong, D, 2000) |
| "Squamous cell carcinoma was diagnosed by histologic examination of a biopsy specimen." | 1.31 | Successful treatment of oral squamous cell carcinoma with intralesional fluorouracil in a Malayan tapir (Tapirus indicus). ( Karpinski, L; Miller, CL; Templeton, RS, 2000) |
| "UFT was administered orally at a dosage of 200 mg/day, 2 times a day, to patients over 80 years of age with oral cancer." | 1.31 | [5-FU concentration in the serum and the tumor tissue after administration of UFT 200 mg/day to patients over 80 years of age with oral cancer]. ( Fukuda, J; Hayatsu, M; Hoshina, H; Iida, A; Kaji, M; Miyamoto, T; Miyaura, Y; Nagashima, K; Ono, K; Takagi, R; Tsurumaki, H, 2000) |
| "Over forty percent patients with squamous cell carcinoma showed moderate chemosensitivity to VM-26, CDDP and E-ADM, and over forty percent cases with adenoid carcinoma showed moderate chemosensitivity to Vm-26, Taxol and E-ADM." | 1.31 | [Chemosensitivity testing of oral and maxillofacial cancer with biopsy specimens]. ( Chen, W; Guo, W; Lin, L; Xu, Q; Zhou, X, 2002) |
| "Fifteen patients with squamous cell carcinoma arising in the gingiva (8), tongue (3), floor of the mouth (1), or maxillary sinus (3) were enrolled." | 1.30 | Intranodal injection of anticancer drugs into fixed cervical metastatic lymph nodes. ( Osaki, T; Ueta, E; Yamamoto, T; Yoneda, K, 1997) |
| "Daily administration of low-dose CDDP and 5-FU combined with radiotherapy was performed in three cases of oral squamous cell carcinoma in aged patients whose general condition was poor." | 1.29 | [Method for daily administration of low-dose CDDP and 5-FU combined with radiotherapy for oral squamous cell carcinoma]. ( Kimura, T; Kishimoto, K; Matsumura, T; Misaki, M; Terakado, N; Yamada, Y, 1995) |
| "Chemosensitivity of salivary gland and oral cancer cell lines to 14 antitumor drugs was tested using a tetrazolium-based colorimetric assay and the relative antitumor activity (RAA) of the drugs was compared." | 1.28 | Chemosensitivity of salivary gland and oral cancer cell lines. ( Chen, JY; Liu, B; Situ, ZQ; Wang, W; Wu, JZ, 1992) |
| "All tumor were squamous cell carcinoma." | 1.28 | [The clinical effect of cisplatin and 5-FU infusion in oral cancer]. ( Hyoudou, I; Ichihara, H; Oka, N; Okuda, T; Okumura, Y; Okutomi, T; Tatematsu, N, 1992) |
| "Thirty-seven patients with oral squamous cell carcinoma, many with advanced disease, were treated initially with a protocol using simultaneous intravenous 5-fluorouracil (5-FU) cis-platinum, and radiation." | 1.28 | Treatment of oral squamous cell carcinoma with simultaneous chemotherapy and radiation: results and surgical implications. ( Adelstein, DJ; Earle, AS; Indresano, AT; Sharan, VM; Vlastou, C, 1990) |
| " With regard to toxicity, the applied treatment schedule (three courses) is fully acceptable, safe and suitable as neoadjuvant chemotherapy in the complex management of oral cavity carcinoma without the risk of delaying subsequent definitive treatment." | 1.28 | [Toxicity of cisplatin with continuous infusion of 5-fluorouracil in neoadjuvant chemotherapy of carcinoma of the oral cavity]. ( Koza, I; Mracna, J; Nagy, V; Poruban, D; Vasko, J, 1989) |
| "Sixty one aged patients with advanced squamous cell carcinoma of the upper aerodigestive tract were given a chemotherapy Cis DDP-5 FU before any local treatment." | 1.28 | [Induction chemotherapy with Cis DDP-5FU in cancers of the upper respiratory and digestive tract after 70 years of age]. ( Camuzard, JF; Demard, F; Falewee, MN; Santini, J; Schneider, M; Thyss, A; Vallicioni, J, 1989) |
| "Average survival for advanced head and neck cancer (AHNC) is 18 months." | 1.27 | Pretreatment with chemotherapy in patients with advanced head and neck cancer. ( Barron, P; Cripps, C; Danjoux, C; de la Bastide, Y; Hardie, J; Nichol, J; Odell, P, 1985) |
| "Five-year results in 60 oral and pharyngeal cancer patients treated with combined approach chemoradiotherapy (39 patients) and chemoradiotherapy plus lymph node surgery (21 patients) are reported." | 1.27 | Oral and pharyngeal cancer: combined approach for multimodal therapy. ( Airoldi, M; Badellino, F; Fazio, M; Gandolfo, S; Manca, A; Sannazzari, GL; Vercellino, V, 1983) |
| "One hundred and eight patients with squamous cell carcinoma of the upper aerodigestive tract (UADT) (T3, T4, NO-N3; 17% stage II, 54% stage III, 27% stage IV) were given three courses of chemotherapy before any local treatment." | 1.27 | Induction chemotherapy with cis-platinum and 5-fluorouracil for squamous cell carcinoma of the head and neck. ( Caldani, C; Chauvel, P; Demard, F; Santini, J; Schneider, M; Thyss, A; Vallicioni, J, 1986) |
| "Seventy-five cases of head and neck cancer except of maxillary sinus, 27 cases of mesopharyngeal cancer, 6 cases of oral cancer, 9 cases of thyroid cancer and 9 cases of the other cancer, were treated with this multi-disciplinary treatment and the results were evaluated in this series." | 1.27 | [An evaluation of multi-disciplinary treatment combined with intra-arterial chemotherapy of head and neck cancer]. ( Maehara, Y; Makino, S; Matsuura, S; Miyama, J; Nakamura, Y; Sakaino, K; Satake, B; Shimizu, R, 1985) |
| "A therapeutical method of inoperable squamous cell carcinomas based on cell kinetics has been applied since 1969 by using 5-fluorine-uracil." | 1.25 | [Radiotherapy of inoperable orofacial squamous epithelial carcinomas following pharmacologically induced partial synchronization]. ( Esser, E; Schumann, J; Wannenmacher, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 84 (27.81) | 18.7374 |
| 1990's | 35 (11.59) | 18.2507 |
| 2000's | 69 (22.85) | 29.6817 |
| 2010's | 86 (28.48) | 24.3611 |
| 2020's | 28 (9.27) | 2.80 |
| Authors | Studies |
|---|---|
| Bui, D | 1 |
| Yin, T | 1 |
| Duan, S | 1 |
| Wei, B | 1 |
| Yang, P | 1 |
| Wong, SJ | 1 |
| You, M | 1 |
| Singh, R | 1 |
| Hu, M | 1 |
| Almeida, LY | 1 |
| Moreira, FDS | 1 |
| Santos, GASD | 1 |
| Cuadra Zelaya, FJM | 1 |
| Ortiz, CA | 1 |
| Agostini, M | 1 |
| Mariano, FS | 1 |
| Bastos, DC | 1 |
| Daher, URN | 1 |
| Kowalski, LP | 1 |
| Coletta, RD | 1 |
| Graner, E | 1 |
| Li, S | 2 |
| Shi, Z | 1 |
| Fu, S | 1 |
| Li, Q | 1 |
| Li, B | 1 |
| Sang, L | 1 |
| Wu, D | 1 |
| Zhao, TC | 3 |
| Zhou, ZH | 1 |
| Ju, WT | 4 |
| Liang, SY | 3 |
| Tang, X | 1 |
| Zhu, DW | 5 |
| Zhang, ZY | 8 |
| Zhong, LP | 8 |
| Yang, KS | 1 |
| Che, PC | 1 |
| Hsieh, MJ | 1 |
| Lee, IN | 1 |
| Wu, YP | 1 |
| Chen, MS | 1 |
| Chen, JC | 1 |
| Chaukar, D | 1 |
| Prabash, K | 1 |
| Rane, P | 1 |
| Patil, VM | 2 |
| Thiagarajan, S | 1 |
| Ghosh-Laskar, S | 1 |
| Sharma, S | 1 |
| Pai, PS | 1 |
| Chaturvedi, P | 1 |
| Pantvaidya, G | 1 |
| Deshmukh, A | 1 |
| Nair, D | 1 |
| Nair, S | 1 |
| Vaish, R | 1 |
| Noronha, V | 2 |
| Patil, A | 1 |
| Arya, S | 1 |
| D'Cruz, A | 1 |
| Li, L | 3 |
| Li, XD | 1 |
| Zhuang, QW | 2 |
| Ge, LY | 1 |
| Li, ZP | 2 |
| Gu, QP | 2 |
| Meng, J | 4 |
| Bollareddy, SR | 1 |
| Krishna, V | 1 |
| Roy, G | 1 |
| Dasari, D | 1 |
| Dhar, A | 1 |
| Venuganti, VVK | 1 |
| Yakita, M | 1 |
| Chujo, T | 1 |
| Wei, FY | 1 |
| Hirayama, M | 1 |
| Kato, K | 2 |
| Takahashi, N | 2 |
| Naganuma, K | 1 |
| Nagata, M | 7 |
| Kawahara, K | 9 |
| Nakayama, H | 8 |
| Tomizawa, K | 1 |
| Fu, JY | 1 |
| Yue, XH | 1 |
| Dong, MJ | 1 |
| Li, J | 13 |
| Zhang, CP | 7 |
| Khamaikawin, W | 1 |
| Locharoenrat, K | 1 |
| Tamane, P | 1 |
| Mahadik, K | 1 |
| Pokharkar, V | 1 |
| Elsaady, SA | 1 |
| Aboushelib, MN | 1 |
| Al-Wakeel, E | 1 |
| Badawi, MF | 1 |
| Klaophimai, S | 1 |
| Pouyfung, P | 1 |
| Chairatvit, K | 1 |
| Liu, Y | 4 |
| Tan, YR | 1 |
| Vangundy, Z | 1 |
| Poi, M | 1 |
| Morsy, RAA | 1 |
| Abbass, EA | 1 |
| Hager, EAA | 1 |
| Farid, MH | 1 |
| Ellithy, MM | 1 |
| Azmy, A | 1 |
| Ma, HL | 1 |
| Wang, LZ | 6 |
| Zhou, G | 1 |
| Hasegawa, H | 1 |
| Kaneko, T | 2 |
| Kanno, C | 1 |
| Endo, M | 2 |
| Yamazaki, M | 1 |
| Kitabatake, T | 1 |
| Monma, T | 1 |
| Takeishi, E | 1 |
| Sato, E | 1 |
| Kano, M | 1 |
| Wen, J | 1 |
| Xu, H | 2 |
| Liu, R | 1 |
| Chen, Q | 3 |
| Dai, Y | 1 |
| Xu, Y | 1 |
| Hitt, R | 1 |
| Iglesias, L | 1 |
| López-Pousa, A | 2 |
| Berrocal-Jaime, A | 1 |
| Grau, JJ | 2 |
| García-Girón, C | 1 |
| Martínez-Trufero, J | 1 |
| Guix, M | 1 |
| Lambea-Sorrosal, J | 1 |
| Del Barco-Morillo, E | 1 |
| León-Vintró, X | 1 |
| Cunquero-Tomas, AJ | 1 |
| Baste, N | 1 |
| Ocaña, A | 1 |
| Cruz-Hernández, JJ | 1 |
| Lee, CC | 1 |
| Hsiao, CY | 1 |
| Lee, SC | 1 |
| Huang, XF | 1 |
| Chang, KF | 1 |
| Lee, MS | 1 |
| Hsieh, MC | 1 |
| Tsai, NM | 1 |
| Lai, KC | 1 |
| Chia, YT | 1 |
| Yih, LH | 1 |
| Lu, YL | 1 |
| Chang, ST | 1 |
| Hong, ZX | 1 |
| Chen, TL | 1 |
| Hour, MJ | 1 |
| Ren, GX | 3 |
| Sun, J | 3 |
| Tu, WY | 3 |
| Hu, YJ | 3 |
| Ji, T | 3 |
| Yang, WJ | 3 |
| He, Y | 5 |
| Wang, YA | 3 |
| Abdel Hamid, HM | 1 |
| Darwish, ZE | 1 |
| Elsheikh, SM | 1 |
| Mourad, GM | 1 |
| Donia, HM | 1 |
| Afifi, MM | 1 |
| Zeng, H | 1 |
| Zhao, X | 1 |
| Tang, C | 1 |
| Ren, G | 2 |
| Ju, H | 1 |
| Wu, Y | 2 |
| Song, H | 1 |
| Ma, X | 1 |
| Ge, M | 1 |
| Qiu, W | 1 |
| Chen, Y | 1 |
| Zhuang, Q | 1 |
| Guo, W | 6 |
| Sun, W | 2 |
| Zhao, T | 1 |
| Aladelusi, TO | 1 |
| Ju, W | 1 |
| Zhang, Z | 1 |
| Zhong, L | 1 |
| Zhu, D | 1 |
| Yang, M | 1 |
| Luo, Q | 2 |
| Chen, X | 3 |
| Chen, F | 4 |
| Chang, PM | 1 |
| Lu, HJ | 1 |
| Wang, LW | 1 |
| Tai, SK | 1 |
| Chen, MH | 1 |
| Chu, PY | 2 |
| Yang, MH | 1 |
| Hung, CC | 1 |
| Chien, CY | 1 |
| Wu, YJ | 1 |
| Lin, CS | 1 |
| Huang, CJ | 1 |
| Chan, LP | 1 |
| Wang, YY | 1 |
| Yuan, SF | 1 |
| Hour, TC | 1 |
| Chen, JY | 2 |
| Inhestern, J | 1 |
| Schmalenberg, H | 2 |
| Dietz, A | 3 |
| Rotter, N | 1 |
| Maschmeyer, G | 2 |
| Jungehülsing, M | 1 |
| Grosse-Thie, C | 1 |
| Kuhnt, T | 2 |
| Görner, M | 1 |
| Sudhoff, H | 2 |
| Wittekindt, C | 1 |
| Guntinas-Lichius, O | 2 |
| Feng, X | 1 |
| Zhang, H | 1 |
| Wang, H | 1 |
| Chen, W | 2 |
| Meng, G | 1 |
| Hirakawa, H | 2 |
| Hanai, N | 2 |
| Suzuki, H | 3 |
| Nishikawa, D | 2 |
| Matayoshi, S | 1 |
| Hasegawa, Y | 2 |
| Suzuki, M | 3 |
| Arita, H | 3 |
| Yoshida, R | 7 |
| Matsuoka, Y | 4 |
| Hirosue, A | 5 |
| Sakata, J | 3 |
| Nakashima, H | 3 |
| Kojima, T | 3 |
| Toya, R | 2 |
| Murakami, R | 2 |
| Hiraki, A | 7 |
| Shinohara, M | 6 |
| Tsuchiya, Y | 2 |
| Ushijima, K | 1 |
| Noguchi, T | 4 |
| Okada, N | 1 |
| Hayasaka, JI | 1 |
| Jinbu, Y | 2 |
| Ando, H | 1 |
| Mori, Y | 1 |
| Kusama, M | 3 |
| Fujimura, A | 1 |
| Eder-Czembirek, C | 2 |
| Sulzbacher, I | 3 |
| Fuereder, T | 1 |
| Selzer, E | 6 |
| Huang, KJ | 1 |
| Kuo, CH | 1 |
| Chen, SH | 1 |
| Lin, CY | 1 |
| Lee, YR | 1 |
| Liang, L | 1 |
| Luo, H | 1 |
| He, Q | 1 |
| You, Y | 1 |
| Fan, Y | 1 |
| Liang, J | 1 |
| Maihoefer, C | 1 |
| Schüttrumpf, L | 1 |
| Macht, C | 1 |
| Pflugradt, U | 1 |
| Hess, J | 1 |
| Schneider, L | 1 |
| Woischke, C | 1 |
| Walch, A | 1 |
| Baumeister, P | 1 |
| Kirchner, T | 1 |
| Zitzelsberger, H | 1 |
| Belka, C | 1 |
| Ganswindt, U | 1 |
| Celentano, A | 1 |
| McCullough, M | 1 |
| Cirillo, N | 1 |
| Rechinger, S | 1 |
| Kornek, G | 2 |
| Seemann, R | 2 |
| Maji, S | 1 |
| Shriwas, O | 1 |
| Samal, SK | 1 |
| Priyadarshini, M | 1 |
| Rath, R | 1 |
| Panda, S | 1 |
| Das Majumdar, SK | 1 |
| Muduly, DK | 1 |
| Dash, R | 1 |
| Huang, WC | 1 |
| Jang, TH | 1 |
| Tung, SL | 1 |
| Yen, TC | 1 |
| Chan, SH | 1 |
| Wang, LH | 1 |
| Akhter, K | 1 |
| Enamur Rashid, M | 1 |
| Pons-Fuster López, E | 1 |
| Gómez García, F | 1 |
| López Jornet, P | 1 |
| Yamamoto, T | 7 |
| Ito, T | 1 |
| Kuwahara, Y | 1 |
| William, WN | 3 |
| Ma, J | 2 |
| Yang, CZ | 2 |
| Yang, X | 1 |
| Myers, JN | 3 |
| Lee, JJ | 3 |
| Wang, B | 1 |
| Zhang, S | 1 |
| Yue, K | 1 |
| Wang, XD | 1 |
| Kuo, YY | 2 |
| Lin, HP | 1 |
| Huo, C | 1 |
| Su, LC | 1 |
| Yang, J | 1 |
| Hsiao, PH | 1 |
| Chiang, HC | 1 |
| Chung, CJ | 1 |
| Wang, HD | 1 |
| Chang, JY | 2 |
| Chen, YW | 1 |
| Chuu, CP | 1 |
| Meng, QF | 1 |
| Zhang, J | 1 |
| Si, YM | 1 |
| Cutilli, T | 2 |
| Leocata, P | 1 |
| Dolo, V | 1 |
| Altobelli, E | 1 |
| Yen, CY | 1 |
| Chiang, WF | 1 |
| Liu, SY | 2 |
| Cheng, PC | 1 |
| Lee, SY | 1 |
| Hong, WZ | 1 |
| Lin, PY | 1 |
| Lin, MH | 2 |
| Liu, YC | 2 |
| Tano, T | 1 |
| Okamoto, M | 1 |
| Kan, S | 1 |
| Bando, T | 1 |
| Goda, H | 1 |
| Nakashiro, K | 1 |
| Shimodaira, S | 1 |
| Koido, S | 1 |
| Homma, S | 1 |
| Fujita, T | 1 |
| Sato, M | 4 |
| Yamashita, N | 1 |
| Hamakawa, H | 2 |
| Kawakami, Y | 1 |
| Patel, K | 1 |
| Foster, NR | 1 |
| Farrell, A | 1 |
| Le-Lindqwister, NA | 1 |
| Mathew, J | 1 |
| Costello, B | 1 |
| Reynolds, J | 1 |
| Meyers, JP | 1 |
| Jatoi, A | 1 |
| Scardina, GA | 1 |
| Cacioppo, A | 1 |
| Messina, P | 1 |
| Tanaka, T | 3 |
| Nakagawa, Y | 5 |
| Takamune, Y | 1 |
| Yoshitake, Y | 3 |
| Lyu, J | 1 |
| Li, C | 1 |
| Wang, R | 1 |
| Bossi, P | 3 |
| Lo Vullo, S | 2 |
| Guzzo, M | 2 |
| Mariani, L | 3 |
| Granata, R | 2 |
| Orlandi, E | 2 |
| Locati, L | 3 |
| Scaramellini, G | 1 |
| Fallai, C | 1 |
| Licitra, L | 4 |
| Yuno, A | 1 |
| Harada, K | 5 |
| Ferdous, T | 3 |
| Ueyama, Y | 3 |
| Maggiore, RJ | 1 |
| Curran, EK | 1 |
| Witt, ME | 2 |
| Haraf, DJ | 2 |
| Vokes, EE | 2 |
| Cohen, EE | 1 |
| Kajihara, A | 2 |
| Takahashi, A | 1 |
| Kondo, N | 1 |
| Mori, E | 1 |
| Kirita, T | 3 |
| Ohnishi, T | 1 |
| Montgomery, B | 1 |
| da Costa, AA | 1 |
| D'Almeida Costa, F | 1 |
| Ribeiro, AR | 1 |
| Guimarães, AP | 1 |
| Chinen, LT | 1 |
| Lopes, CA | 1 |
| de Lima, VC | 1 |
| Jin, J | 1 |
| Ye, MC | 1 |
| Wang, LP | 1 |
| Li, RX | 1 |
| Zhou, Y | 2 |
| Wang, Y | 2 |
| Zhu, WZ | 1 |
| Zuo, Y | 1 |
| Liu, SH | 1 |
| Shimomura, H | 1 |
| Sasahira, T | 1 |
| Yamanaka, Y | 1 |
| Kurihara, M | 1 |
| Imai, Y | 2 |
| Tamaki, S | 1 |
| Yamakawa, N | 2 |
| Shirone, N | 1 |
| Hasegawa, M | 1 |
| Kuniyasu, H | 1 |
| Chen, YK | 1 |
| Huang, AH | 1 |
| Lin, LM | 1 |
| León, X | 1 |
| Agüero, A | 1 |
| López, M | 1 |
| García, J | 1 |
| Farré, N | 1 |
| Quer, M | 1 |
| Nakamura, T | 2 |
| Shinriki, S | 1 |
| Jono, H | 1 |
| Ueda, M | 1 |
| Guo, J | 1 |
| Hayashi, M | 1 |
| Ota, T | 1 |
| Ota, K | 2 |
| Yamashita, S | 1 |
| Ando, Y | 2 |
| Ozawa, T | 1 |
| Nakashima, T | 1 |
| Wu, CF | 1 |
| Wu, CS | 1 |
| Yu, WW | 1 |
| Huang, MY | 1 |
| Budach, V | 2 |
| Stromberger, C | 1 |
| Poettgen, C | 1 |
| Baumann, M | 1 |
| Budach, W | 2 |
| Grabenbauer, G | 2 |
| Marnitz, S | 1 |
| Olze, H | 1 |
| Wernecke, KD | 1 |
| Ghadjar, P | 1 |
| Li, X | 2 |
| Zhao, B | 1 |
| Shang, D | 1 |
| Zhong, M | 1 |
| Deng, C | 1 |
| Jia, X | 1 |
| Zhang, X | 1 |
| Ding, X | 1 |
| Li, H | 1 |
| Geng, M | 1 |
| Xie, Z | 1 |
| Wu, H | 1 |
| Huang, M | 1 |
| Sadighi, S | 1 |
| Keyhani, A | 1 |
| Harirchi, I | 1 |
| Garajei, A | 1 |
| Aghili, M | 1 |
| Kazemian, A | 1 |
| Motiee Langroudi, M | 1 |
| Zendehdel, K | 1 |
| Nikparto, N | 1 |
| Ryoo, I | 1 |
| Kim, JH | 1 |
| Choi, SH | 1 |
| Sohn, CH | 1 |
| Kim, SC | 1 |
| Hong, CS | 1 |
| Zhu, HG | 2 |
| Cai, YL | 2 |
| Yin, QM | 1 |
| Wang, ZH | 2 |
| Ye, WM | 2 |
| Xu, LQ | 2 |
| Zhuang, Z | 1 |
| Zhao, H | 1 |
| Feng, H | 1 |
| Liu, D | 1 |
| Liu, J | 2 |
| Ji, N | 3 |
| Luo, X | 1 |
| Dan, H | 1 |
| Zeng, X | 2 |
| Sun, C | 1 |
| Ju, X | 1 |
| Zhou, M | 2 |
| Yang, H | 1 |
| Liang, X | 1 |
| Chu, L | 1 |
| Jiang, L | 2 |
| Uchiyama, K | 1 |
| Yamada, M | 1 |
| Tamate, S | 1 |
| Iwasaki, K | 1 |
| Mitomo, K | 1 |
| Nakayama, S | 1 |
| Luo, SD | 1 |
| Chen, YJ | 1 |
| Liu, CT | 1 |
| Rau, KM | 1 |
| Chen, YC | 1 |
| Tsai, HT | 1 |
| Chen, CH | 1 |
| Chiu, TJ | 1 |
| Hiraiwa, T | 1 |
| Koike, M | 1 |
| Okada, H | 1 |
| Senda, N | 1 |
| Suzuki, K | 1 |
| Schmaltz, H | 1 |
| Borel, C | 1 |
| Ciftci, S | 1 |
| Takeda-Raguin, C | 1 |
| Debry, C | 1 |
| Schultz, P | 1 |
| Dupret-Bories, A | 1 |
| Harada, T | 1 |
| Peng, HY | 1 |
| Cheng, YC | 1 |
| Hsu, YM | 1 |
| Wu, GH | 1 |
| Kuo, CC | 1 |
| Liou, JP | 1 |
| Jin, SL | 1 |
| Shiah, SG | 1 |
| Joshi, A | 1 |
| Banavali, SD | 1 |
| Muddu, V | 1 |
| Prabhash, K | 1 |
| Deng, P | 1 |
| Liao, G | 2 |
| Lin, Y | 2 |
| Feng, M | 1 |
| Wang, TY | 1 |
| Peng, CY | 1 |
| Lee, SS | 1 |
| Chou, MY | 1 |
| Yu, CC | 1 |
| Chang, YC | 1 |
| Ye, M | 1 |
| Liu, W | 1 |
| Tao, H | 1 |
| Yan, J | 1 |
| Bergamini, C | 1 |
| Miceli, R | 1 |
| Cova, A | 1 |
| Resteghini, C | 1 |
| Alfieri, S | 1 |
| Imbimbo, M | 1 |
| Iacovelli, NA | 1 |
| Huber, V | 1 |
| Cavallo, A | 1 |
| Rivoltini, L | 1 |
| Yoshiba, S | 1 |
| Ito, D | 2 |
| Nagumo, T | 1 |
| Shirota, T | 1 |
| Hatori, M | 2 |
| Shintani, S | 2 |
| Shinohara, F | 2 |
| Sugazaki, M | 1 |
| Echigo, S | 2 |
| Rikiishi, H | 2 |
| Tateishi, Y | 1 |
| Tatemoto, Y | 1 |
| Ohno, S | 1 |
| Morishita, K | 1 |
| Ueta, E | 3 |
| Kuang, YH | 1 |
| Su, J | 1 |
| Wu, LS | 1 |
| Liao, LQ | 1 |
| Li, D | 2 |
| Chen, ZS | 1 |
| Kanekura, T | 1 |
| Matsumoto, K | 1 |
| Matsumura, T | 2 |
| Hoshi, K | 1 |
| Ito, H | 1 |
| Osano, H | 2 |
| Kovács, AF | 5 |
| Eberlein, K | 1 |
| Hülsmann, T | 1 |
| Klug, C | 4 |
| Berzaczy, D | 1 |
| Voracek, M | 3 |
| Nell, C | 1 |
| Ploder, O | 2 |
| Millesi, W | 5 |
| Ewers, R | 5 |
| Yamashita, T | 1 |
| Toida, M | 1 |
| Long, NK | 1 |
| Miyazaki, Y | 1 |
| Asaka, Y | 1 |
| Hatakeyama, D | 1 |
| Yonemoto, K | 1 |
| Makita, H | 1 |
| Kato, Y | 1 |
| Shibata, T | 1 |
| Uchida, D | 2 |
| Onoue, T | 1 |
| Begum, NM | 1 |
| Kuribayashi, N | 2 |
| Tomizuka, Y | 1 |
| Tamatani, T | 4 |
| Nagai, H | 3 |
| Miyamoto, Y | 2 |
| Mroz, EA | 1 |
| Rocco, JW | 1 |
| Perrone, F | 1 |
| Cortelazzi, B | 1 |
| Quattrone, P | 2 |
| Pierotti, MA | 1 |
| Pilotti, S | 1 |
| Giannola, LI | 2 |
| De Caro, V | 2 |
| Giandalia, G | 2 |
| Siragusa, MG | 2 |
| Paderni, C | 2 |
| Campisi, G | 2 |
| Florena, AM | 1 |
| Mesía, R | 1 |
| Palmero, R | 1 |
| Cos, M | 1 |
| Vilajosana, E | 1 |
| Vázquez, S | 1 |
| Rades, D | 1 |
| Kronemann, S | 1 |
| Meyners, T | 1 |
| Bohlen, G | 1 |
| Tribius, S | 1 |
| Kazic, N | 1 |
| Schroeder, U | 1 |
| Hakim, SG | 1 |
| Schild, SE | 1 |
| Dunst, J | 1 |
| Itashiki, Y | 1 |
| Takenawa, T | 1 |
| Su, L | 1 |
| Xiao, M | 1 |
| Yu, L | 1 |
| Alieva, SB | 1 |
| Tkachev, SI | 1 |
| Romanov, IS | 1 |
| Zaderenko, IA | 1 |
| Tiuliandin, SA | 1 |
| Chen, XR | 1 |
| Lu, R | 1 |
| Dan, HX | 1 |
| Li, XY | 1 |
| Pederson, AW | 1 |
| Salama, JK | 1 |
| Stenson, KM | 1 |
| Blair, EA | 1 |
| Cho, JH | 1 |
| Lee, MH | 1 |
| Cho, YJ | 1 |
| Park, BS | 1 |
| Kim, S | 2 |
| Kim, GC | 1 |
| Ceschia, A | 1 |
| Fukuma, D | 1 |
| Sprio, AE | 1 |
| Di Scipio, F | 1 |
| Ceppi, P | 1 |
| Salamone, P | 1 |
| Di Carlo, F | 1 |
| Scagliotti, GV | 1 |
| Papotti, M | 1 |
| Ceccarelli, A | 1 |
| Berta, GN | 1 |
| Tabachnyk, M | 1 |
| Distel, LV | 1 |
| Büttner, M | 1 |
| Grabenbauer, GG | 1 |
| Nkenke, E | 1 |
| Fietkau, R | 1 |
| Lubgan, D | 1 |
| Peng, B | 1 |
| Yi, S | 1 |
| Gu, Y | 1 |
| Zheng, G | 1 |
| He, Z | 1 |
| Fucarino, A | 1 |
| Marino Gammazza, A | 1 |
| Pitruzzella, A | 1 |
| Marciano, V | 1 |
| Compilato, D | 1 |
| Holgate, ST | 1 |
| Davies, DE | 1 |
| Farina, F | 1 |
| Zummo, G | 1 |
| Bucchieri, F | 1 |
| Takamaru, N | 1 |
| Hara, K | 1 |
| Kinouchi, M | 1 |
| Ohe, G | 1 |
| Fujisawa, K | 1 |
| Dalirsani, Z | 1 |
| Farajnia, S | 1 |
| Javadzadeh, Y | 1 |
| Mehdipour, M | 1 |
| Koozegari, S | 1 |
| Perisanidis, C | 1 |
| Mittlböck, M | 1 |
| Mitchell, D | 1 |
| Czembirek, C | 1 |
| Schopper, C | 1 |
| Oertel, K | 1 |
| Spiegel, K | 1 |
| Wendt, TG | 1 |
| Larizadeh, MH | 1 |
| Shabani, M | 1 |
| Fan, XD | 1 |
| Wang, BS | 1 |
| Kies, MS | 1 |
| Arcangeli, G | 1 |
| Saracino, B | 1 |
| Danesi, DT | 1 |
| De Campora, E | 1 |
| Giovinazzo, G | 1 |
| Cognetti, F | 2 |
| Carlini, P | 2 |
| Arcangeli, S | 1 |
| Mecozzi, A | 1 |
| Domingo, J | 1 |
| Blanch, JL | 1 |
| Verger, E | 1 |
| Castro, V | 1 |
| Nadal, A | 1 |
| Alós, L | 1 |
| Estapé, J | 1 |
| Brown, TA | 1 |
| Ridge, JA | 1 |
| Goldberg, M | 1 |
| Yamamoto, G | 2 |
| Tanaka, A | 2 |
| Tsuda, Y | 2 |
| Shimada, T | 2 |
| Nishida, T | 2 |
| Nishikawa, M | 1 |
| Inoda, H | 1 |
| Takigami, K | 2 |
| Yoshitake, K | 2 |
| Ita, M | 1 |
| Okafuji, M | 1 |
| Fukuda, K | 1 |
| Mitsuoka, K | 1 |
| Hanakita, T | 1 |
| Hayatsu, Y | 1 |
| Neuburg, J | 1 |
| Glaser, C | 2 |
| Schwarz, B | 1 |
| Kermer, C | 3 |
| Grandi, C | 1 |
| Valvo, F | 1 |
| Valagussa, P | 1 |
| Bonadonna, G | 1 |
| Molinari, R | 1 |
| Cantù, G | 1 |
| Salesiotis, A | 1 |
| Soong, R | 1 |
| Diasio, RB | 1 |
| Frost, A | 1 |
| Cullen, KJ | 1 |
| Zhou, X | 2 |
| Xu, Q | 1 |
| Lin, L | 1 |
| Andreadis, C | 1 |
| Vahtsevanos, K | 1 |
| Sidiras, T | 1 |
| Thomaidis, I | 1 |
| Antoniadis, K | 1 |
| Mouratidou, D | 1 |
| Liu, S | 1 |
| Liao, C | 1 |
| Wang, D | 1 |
| Iwase, M | 2 |
| Watanabe, H | 1 |
| Kondo, G | 1 |
| Ohashi, M | 1 |
| Nagumo, M | 2 |
| Yamaoka, K | 1 |
| Fukuda, M | 1 |
| Kuwajima, S | 1 |
| Hagiwara, H | 1 |
| Toshima, S | 1 |
| Matsuoka, A | 1 |
| Ohnuki, T | 1 |
| Seki, H | 1 |
| Iino, M | 1 |
| Sageshima, M | 1 |
| Yusa, H | 1 |
| Yoshida, H | 2 |
| Noguchi, M | 2 |
| Ohara, K | 1 |
| FLETCHER, GH | 1 |
| SUIT, HD | 1 |
| HOWE, CD | 1 |
| SAMUELS, M | 1 |
| JESSE, RH | 3 |
| VILLAREAL, RU | 1 |
| VILLARREAL, R | 1 |
| LETAYF, V | 1 |
| RUFINO, C | 1 |
| HICKEY, RC | 1 |
| GOLLIN, FF | 5 |
| ANSFIELD, FJ | 4 |
| VERMUND, H | 4 |
| DESPREZ, JD | 1 |
| KIEHN, CL | 1 |
| BENSON, JW | 2 |
| DAMM, H | 1 |
| BAKER, RR | 1 |
| GAERTNER, RA | 1 |
| JOHNSON, RO | 3 |
| KISKEN, WA | 1 |
| CURRERI, AR | 1 |
| Schmidberger, H | 1 |
| Rave-Fränk, M | 1 |
| Hille, A | 1 |
| Pradier, O | 1 |
| Hess, CF | 1 |
| Wiltfang, J | 1 |
| Bloch-Birkholz, A | 1 |
| Leher, A | 1 |
| Neukam, FW | 1 |
| Kessler, P | 1 |
| Ghahremani, MT | 2 |
| Stefenelli, U | 1 |
| Bitter, K | 1 |
| Lou, E | 1 |
| Kellman, RM | 1 |
| Hutchison, R | 1 |
| Shillitoe, EJ | 1 |
| Li, MH | 1 |
| Sanada, M | 1 |
| Odani, T | 1 |
| Azuma, M | 2 |
| Ashida, Y | 2 |
| Motegi, K | 2 |
| Takashima, R | 1 |
| Kawaguchi, S | 1 |
| Ohbayashi, Y | 2 |
| Miyake, M | 2 |
| Iwasaki, A | 2 |
| Ogawa, T | 1 |
| Nagahata, S | 2 |
| Toyama, Y | 1 |
| Ohkawa, M | 1 |
| Huang, GC | 1 |
| Tanimoto, K | 1 |
| Shimokuni, T | 1 |
| Ukon, K | 1 |
| Tsujimoto, H | 1 |
| Fukushima, M | 1 |
| Hiyama, K | 1 |
| Nishiyama, M | 1 |
| Iguchi, H | 1 |
| Kusuki, M | 1 |
| Nakamura, A | 1 |
| Nishiura, H | 1 |
| Kanazawa, A | 1 |
| Takayama, M | 1 |
| Sunami, K | 1 |
| Yamane, H | 1 |
| Kobayashi, H | 2 |
| Koike, T | 2 |
| Nakatsuka, A | 1 |
| Kurita, H | 2 |
| Sagara, J | 1 |
| Taniguchi, S | 1 |
| Kurashina, K | 2 |
| Takemura, K | 2 |
| Ogi, K | 1 |
| Tokino, T | 1 |
| Kubota, H | 1 |
| Miyazaki, A | 2 |
| Kohama, G | 1 |
| Hiratsuka, H | 2 |
| Wutzl, A | 2 |
| Poeschl, PW | 1 |
| Oeckher, M | 1 |
| Ruggeri, EM | 1 |
| Pollera, CF | 1 |
| De Marco, S | 1 |
| Ruscito, P | 1 |
| Pinnarò, P | 1 |
| Nardi, M | 1 |
| Giannarelli, D | 1 |
| Yanamoto, S | 2 |
| Iwamoto, T | 1 |
| Kawasaki, G | 2 |
| Yoshitomi, I | 2 |
| Baba, N | 1 |
| Mizuno, A | 2 |
| Umeda, M | 1 |
| Komatsubara, H | 1 |
| Ojima, Y | 1 |
| Minamikawa, T | 1 |
| Shigeta, T | 1 |
| Shibuya, Y | 1 |
| Yokoo, S | 1 |
| Komori, T | 1 |
| Kariya, S | 1 |
| Kosaka, M | 1 |
| Orita, Y | 1 |
| Akagi, H | 1 |
| Nishizaki, K | 1 |
| Yamshita, Y | 1 |
| Shikimori, M | 1 |
| Goto, M | 1 |
| Miyazawa, H | 1 |
| Uehara, S | 1 |
| Sasabe, E | 1 |
| Oku, N | 1 |
| Osaki, T | 5 |
| Vikhlianov, IV | 1 |
| Shoĭket, IaN | 1 |
| Lazarev, AF | 1 |
| Murakami, J | 1 |
| Lee, YJ | 1 |
| Kokeguchi, S | 1 |
| Tsujigiwa, H | 1 |
| Asaumi, J | 1 |
| Nagatsuka, H | 1 |
| Fukui, K | 1 |
| Kuroda, M | 1 |
| Tanaka, N | 3 |
| Matsubara, N | 1 |
| Maruoka, Y | 2 |
| Ando, T | 2 |
| Ogiuchi, Y | 2 |
| Ogiuchi, H | 2 |
| Kobayashi, J | 1 |
| Kido, Y | 1 |
| Abe, M | 1 |
| Tomihara, K | 1 |
| Dehari, H | 1 |
| Nakamori, K | 1 |
| Nagai, I | 1 |
| Nishimura, K | 1 |
| Aoki, K | 1 |
| Tatebayashi, S | 1 |
| Yagyuu, T | 1 |
| Nakagawa, H | 1 |
| Bootz, F | 1 |
| Fuwa, N | 1 |
| Kodaira, T | 1 |
| Furutani, K | 1 |
| Tachibana, H | 1 |
| Nakahara, R | 1 |
| Tomoda, T | 1 |
| Inokuchi, H | 1 |
| Daimon, T | 1 |
| Keilholz, U | 1 |
| Werner, J | 1 |
| Hagen, R | 1 |
| Flentje, M | 2 |
| Iro, H | 1 |
| Wang, A | 1 |
| Jiang, W | 1 |
| Guan, Z | 1 |
| Dhawan, IK | 1 |
| Thakur, NS | 1 |
| Madan, NC | 1 |
| Bannerjee, A | 1 |
| Sahoo, BK | 1 |
| Khanna, NN | 1 |
| Srivastava, PK | 1 |
| Khanna, S | 1 |
| Das, SN | 1 |
| Dolnick, BJ | 1 |
| Pink, JJ | 1 |
| Inuyama, Y | 2 |
| Horiuchi, M | 1 |
| Kohno, N | 2 |
| Mashino, S | 1 |
| Ozu, R | 1 |
| Asaoka, K | 1 |
| Kaneda, T | 1 |
| Fujimoto, Y | 1 |
| Shinozuka, J | 1 |
| Su, P | 1 |
| Will, CH | 1 |
| Hering, KG | 1 |
| Dieckmann, J | 1 |
| Spaulding, MB | 1 |
| Vasquez, J | 1 |
| Khan, A | 1 |
| Sundquist, N | 2 |
| Lorè, JM | 2 |
| Fazio, M | 4 |
| Badellino, F | 1 |
| Sannazzari, GL | 1 |
| Vercellino, V | 5 |
| Airoldi, M | 6 |
| Manca, A | 1 |
| Gandolfo, S | 4 |
| Yanagawa, T | 1 |
| Yura, Y | 1 |
| Sugi, M | 1 |
| Hamada, S | 1 |
| Miyazaki, T | 1 |
| Preda, G | 1 |
| Cattaneo, V | 1 |
| Fazio, N | 1 |
| Mastromatteo, V | 1 |
| Negri, L | 2 |
| Pecchio, F | 1 |
| Tripodina, A | 1 |
| Diaz-Ordaz, E | 1 |
| Spaulding, M | 1 |
| Chary, K | 1 |
| Kaufman, S | 1 |
| Lawrence, W | 1 |
| Hong, F | 1 |
| Gerold, T | 1 |
| Barrali, RA | 1 |
| Munakata, H | 2 |
| Kayada, Y | 2 |
| Kawahara, M | 2 |
| Sakamoto, T | 2 |
| Yoshiga, K | 1 |
| Takada, K | 2 |
| Stuschke, M | 1 |
| Dinges, S | 1 |
| Jahnke, K | 1 |
| Heselmann, I | 1 |
| Unger, A | 1 |
| Stüben, G | 1 |
| Sack, H | 1 |
| Yoneda, K | 3 |
| Umazume, M | 1 |
| Kishimoto, K | 1 |
| Kimura, T | 1 |
| Misaki, M | 1 |
| Yamada, Y | 1 |
| Terakado, N | 2 |
| Zöller, J | 2 |
| Born, IA | 2 |
| Osswald, H | 1 |
| Pomatto, E | 2 |
| Berutto, M | 1 |
| Falco, V | 1 |
| Bocca, M | 1 |
| Valente, G | 1 |
| Corradi, L | 1 |
| Tardy, A | 1 |
| Bertetto, O | 1 |
| Palestro, G | 1 |
| Depondt, J | 1 |
| Gehanno, P | 1 |
| Martin, M | 1 |
| Lelievre, G | 1 |
| Guerrier, B | 1 |
| Peytral, C | 1 |
| Schott, H | 1 |
| Pellae-Cosset, B | 1 |
| Recchia, F | 1 |
| Lelli, S | 1 |
| Di Matteo, G | 1 |
| Rea, S | 1 |
| Frati, L | 1 |
| van der Wilt, CL | 1 |
| Visser, GW | 1 |
| Braakhuis, BJ | 1 |
| Wedzinga, R | 1 |
| Noordhuis, P | 1 |
| Smid, K | 1 |
| Peters, GJ | 1 |
| del Campo, JM | 2 |
| Felip, E | 1 |
| Giralt, J | 1 |
| Raspall, G | 2 |
| Bescos, S | 2 |
| Casado, S | 1 |
| Maldonado, X | 1 |
| Papola, F | 1 |
| Corbacelli, A | 1 |
| ElAttar, TM | 1 |
| Virji, AS | 1 |
| Sato, A | 1 |
| Kumagai, S | 1 |
| Sakaki, K | 1 |
| Morikawa, H | 1 |
| Song, ST | 1 |
| Mori, S | 1 |
| Fujieda, S | 2 |
| Sunaga, H | 2 |
| Tsuzuki, H | 2 |
| Saito, H | 2 |
| Matiakin, EG | 1 |
| Uvarov, AA | 1 |
| Kropotov, MA | 1 |
| Azizian, RI | 1 |
| Lin, JC | 1 |
| Jan, JS | 1 |
| Hsu, CY | 1 |
| Wong, DY | 1 |
| Noda, I | 1 |
| Sugimoto, C | 1 |
| Volling, P | 1 |
| Schröder, M | 1 |
| Eckel, H | 1 |
| Ebeling, O | 1 |
| Stennert, E | 1 |
| Turowski, B | 1 |
| Loitz, M | 1 |
| Tong, D | 1 |
| Poot, M | 1 |
| Hu, D | 1 |
| Oda, D | 1 |
| Giralt, JL | 1 |
| Gonzalez, J | 1 |
| Maldonado, J | 1 |
| Sanz, X | 1 |
| Pamias, J | 1 |
| Eraso, A | 1 |
| Miller, CL | 1 |
| Templeton, RS | 1 |
| Karpinski, L | 1 |
| Iida, A | 1 |
| Takagi, R | 1 |
| Hoshina, H | 1 |
| Ono, K | 1 |
| Kaji, M | 1 |
| Tsurumaki, H | 1 |
| Fukuda, J | 1 |
| Nagashima, K | 1 |
| Miyaura, Y | 1 |
| Hayatsu, M | 1 |
| Miyamoto, T | 1 |
| Tanizaki, A | 1 |
| Watanabe, S | 1 |
| Numao, A | 1 |
| Wang, HM | 1 |
| Ng, SH | 1 |
| Wang, CH | 1 |
| Liaw, CT | 1 |
| Chen, JS | 1 |
| Yang, TS | 1 |
| Chen, IH | 1 |
| Glaser, CM | 1 |
| Kornek, GV | 1 |
| Lang, S | 1 |
| Schüll, B | 1 |
| Watzinger, F | 1 |
| Lavey, RS | 1 |
| Ishida, Y | 1 |
| Iba, T | 1 |
| Nakata, T | 1 |
| Ohtsuki, T | 1 |
| Yamaguchi, Y | 1 |
| Grüterich, G | 1 |
| Wagner, M | 1 |
| Hoshino, M | 1 |
| Nishihara, N | 1 |
| Okamoto, T | 1 |
| Fukada, K | 1 |
| Kuwazawa, T | 1 |
| Kayahara, H | 1 |
| Okuda, M | 1 |
| El-Domeiri, AA | 1 |
| Chaudhuri, P | 1 |
| Price, LA | 1 |
| Hill, BT | 1 |
| Calvert, AH | 1 |
| Shaw, HJ | 1 |
| Hughes, KB | 1 |
| Bertino, JR | 1 |
| Boston, B | 1 |
| Capizzi, RL | 1 |
| Esser, E | 3 |
| Schumann, J | 2 |
| Wannenmacher, M | 4 |
| Goldsmith, MA | 1 |
| Carter, SK | 1 |
| Helpap, B | 1 |
| Herberhold, C | 1 |
| Thelen, M | 1 |
| Stiens, R | 1 |
| Koch, U | 1 |
| Perlin, E | 1 |
| Oberfield, RA | 1 |
| Lo, TC | 1 |
| Wiley, AL | 1 |
| Brandenburg, JH | 2 |
| Davis, HL | 2 |
| Ramirez, G | 3 |
| Mitrov, G | 1 |
| Penchev, P | 1 |
| Khristov, K | 1 |
| Mushmov, M | 1 |
| Pandova, V | 1 |
| Kurka, M | 1 |
| Orfanos, CE | 1 |
| Pullmann, H | 1 |
| Dietz, R | 1 |
| Mootz, W | 1 |
| Wu, JZ | 1 |
| Situ, ZQ | 1 |
| Liu, B | 1 |
| Wang, W | 1 |
| Poruban, D | 2 |
| Koza, I | 2 |
| Mracna, J | 2 |
| Nagy, V | 2 |
| Vasko, J | 2 |
| Okutomi, T | 1 |
| Ichihara, H | 1 |
| Okuda, T | 1 |
| Okumura, Y | 1 |
| Hyoudou, I | 1 |
| Tatematsu, N | 1 |
| Oka, N | 1 |
| Altermatt, HJ | 1 |
| Gebbers, JO | 1 |
| Laissue, JA | 1 |
| Tomita, Y | 2 |
| Ozaki, T | 1 |
| Samoun, M | 1 |
| Potocka, AC | 1 |
| Pillière, R | 1 |
| Delorme, G | 1 |
| Prinseau, J | 1 |
| Baglin, A | 1 |
| Dobrowsky, W | 4 |
| Dobrowsky, E | 3 |
| Strassl, H | 4 |
| Braun, O | 3 |
| Gritzmann, N | 2 |
| Scheiber, V | 2 |
| Mende, U | 1 |
| Drommer, RB | 1 |
| Reichardt, P | 1 |
| Earle, AS | 1 |
| Adelstein, DJ | 1 |
| Vlastou, C | 1 |
| Sharan, VM | 1 |
| Indresano, AT | 1 |
| Bohno, K | 1 |
| Ushijima, T | 1 |
| Takeda, H | 1 |
| Numata, S | 1 |
| Laccourreye, H | 2 |
| Bassot, V | 2 |
| Lacau St Guily, J | 2 |
| Brasnu, D | 2 |
| Menard, M | 1 |
| Donnadieu, S | 1 |
| Jacquillat, C | 2 |
| Cripps, C | 1 |
| Odell, P | 1 |
| Danjoux, C | 1 |
| Nichol, J | 1 |
| de la Bastide, Y | 1 |
| Barron, P | 1 |
| Hardie, J | 1 |
| Kun, LE | 1 |
| Toohill, RJ | 1 |
| Holoye, PY | 1 |
| Duncavage, JA | 1 |
| Byhardt, RW | 1 |
| Ritch, PS | 1 |
| Grossman, TW | 1 |
| Hoffmann, RG | 1 |
| Cox, JD | 1 |
| Malin, T | 1 |
| Weil, M | 1 |
| Calais, G | 1 |
| Goga, D | 1 |
| Le Flock, O | 1 |
| Ballon, G | 1 |
| Görögh, T | 1 |
| Eickbohm, JE | 1 |
| Lippert, B | 1 |
| Holdener, EE | 1 |
| Braun, OM | 1 |
| Neumeister, B | 1 |
| Neuhold, N | 1 |
| Siebenhandl, A | 1 |
| Wimmer, M | 1 |
| Holzner, JH | 1 |
| Popp, W | 1 |
| Tsukuda, M | 1 |
| Yanoma, S | 1 |
| Ono, T | 2 |
| Sudo, K | 1 |
| Sawaki, S | 1 |
| Ganzer, U | 1 |
| Tanaka, J | 1 |
| Takaoka, T | 1 |
| Hosoda, H | 1 |
| Fujii, M | 1 |
| Maxson, BB | 1 |
| Scott, RF | 1 |
| Headington, JT | 1 |
| Gorbunova, VA | 1 |
| Liubaev, VL | 1 |
| Shatikhin, VA | 1 |
| Brzhezovskiĭ, VZh | 1 |
| Pustynskiĭ, IN | 1 |
| Demard, F | 2 |
| Falewee, MN | 1 |
| Santini, J | 2 |
| Camuzard, JF | 1 |
| Thyss, A | 2 |
| Vallicioni, J | 2 |
| Schneider, M | 2 |
| Imano, Y | 1 |
| Hayashizaki, K | 1 |
| Rausch, EM | 1 |
| Kishi, T | 1 |
| Sato, T | 1 |
| Horikoshi, M | 1 |
| Enomoto, S | 1 |
| Pedani, F | 4 |
| Brando, V | 2 |
| Gabriele, P | 1 |
| Orecchia, R | 1 |
| Saito, Y | 1 |
| Uchiyama, G | 1 |
| Hayashi, S | 2 |
| Araki, T | 1 |
| Hihara, T | 1 |
| Seto, K | 1 |
| Hayakawa, K | 1 |
| Ohnishi, M | 1 |
| Kambayashi, H | 1 |
| Oyama, T | 1 |
| Sridhar, KS | 1 |
| Caldani, C | 1 |
| Chauvel, P | 1 |
| Ozzello, F | 3 |
| Camoletto, D | 1 |
| Matsuura, S | 1 |
| Makino, S | 1 |
| Satake, B | 1 |
| Shimizu, R | 1 |
| Sakaino, K | 1 |
| Maehara, Y | 1 |
| Nakamura, Y | 1 |
| Miyama, J | 1 |
| Ryan, RF | 1 |
| Krementz, ET | 2 |
| Truesdale, GL | 1 |
| Mayer, M | 1 |
| Colon, J | 1 |
| Donegan, WL | 1 |
| Harris, HS | 1 |
| Couture, J | 2 |
| Deschênes, L | 1 |
| Richard, JM | 1 |
| Sancho, H | 1 |
| Nervi, C | 1 |
| Casale, C | 1 |
| Cortese, M | 1 |
| Michelet, FX | 1 |
| Benoit, JP | 1 |
| Cruz, AB | 1 |
| McInnis, WD | 1 |
| Aust, JB | 1 |
| Glupe, J | 1 |
| Hattowska, H | 1 |
| Borowicz, K | 1 |
| Freckman, HA | 1 |
| Kaulen-Becker, L | 1 |
| Priestman, TJ | 1 |
| Nitze, HR | 1 |
| Kokame, GM | 1 |
| Takayama, I | 1 |
| Katsumi, Y | 1 |
| Shozu, R | 1 |
| Obert, G | 1 |
| Tripier, F | 1 |
| Guir, J | 1 |
| Korbitz, BC | 1 |
| Hayashi, H | 1 |
| Narita, Y | 1 |
| Saito, S | 1 |
| Saito, M | 1 |
| Von Essen, CF | 1 |
| Joseph, LB | 1 |
| Simon, GT | 1 |
| Singh, AD | 1 |
| Singh, SP | 1 |
| Israel, L | 1 |
| Bernard, E | 1 |
| Goepfert, H | 1 |
| Lindberg, RD | 1 |
| Johnson, RH | 1 |
| Chakravorty, RC | 1 |
| Sarkar, SK | 1 |
| Mukerji, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Phase III Trial Comparing Induction Chemotherapy With Cisplatin/5-fluorouracil (PF) or Docetaxel/Cisplatin/5-fluorouracil (TPF) Plus Chemoradiotherapy (CRT) Versus CRT Alone as First-line Treatment or Unresectable Locally Advanced Head and Neck[NCT00261703] | Phase 2/Phase 3 | 439 participants (Actual) | Interventional | 2002-12-31 | Completed | ||
| Study of TPF (Docetaxel, Cisplatin, 5-fluorouracil) Induction Chemotherapy Followed by Surgery and Radiotherapy in Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma[NCT01542931] | Phase 2/Phase 3 | 256 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Phase I/II Study of Split-dose TPF-Induction Chemotherapy Before Surgery of Oropharyngeal and Cavity of the Mouth Cancer[NCT01108042] | Phase 1/Phase 2 | 71 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Microbiota, Inflammatory Environment, Clinical and Radiomic Features as Predictors of Normal Tissue Response in Radiotherapy for Prostate and Head-and-neck Cancer[NCT03294122] | 400 participants (Anticipated) | Observational | 2017-02-02 | Recruiting | |||
| Phase I Study of Cabazitaxel - Platinum Fluorouracil Induction Chemotherapy in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck[NCT01379339] | Phase 1 | 40 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| A Prospective, Single-arm, Phase II Study of Adelbelimab Combined With Carboplatin and Nab-paclitaxel in Neoadjuvant Therapy for Patients With Resectable Locally Advanced Squamous Cell Carcinoma of the Head and Neck[NCT06016413] | Phase 2 | 30 participants (Anticipated) | Interventional | 2023-09-01 | Not yet recruiting | ||
| A Pilot Study of Paclitaxel With Radiation Therapy for Locally Advanced Head and Neck Cancer[NCT00001442] | Phase 1 | 35 participants | Interventional | 1995-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for fluorouracil and Mouth Neoplasms
| Article | Year |
|---|---|
Oral cancer chemotherapy adherence and adherence assessment tools: a report from North Central Cancer Group Trial N0747 and a systematic review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase II as Top | 2013 |
Preoperative Chemotherapy and Metronomic Scheduling of Chemotherapy in Locally Advanced Oral Cancers.
Topics: Administration, Metronomic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Fl | 2016 |
[Current role for induction chemotherapy in head and neck tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 2008 |
The integration of chemotherapy into a combined modality approached to cancer therapy. V. Squamous cell cancer of the head and neck.
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Administration Schedule; Drug Therapy, Combination; Fluoro | 1975 |
Short-term results of the combination of cis-platinum, 5-fluorouracil and bleomycin in advanced upper aerodigestive tract cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Clinical Trials as Topic; Comb | 1986 |
Management of oral squamous cell carcinoma in situ with topical 5-fluorouracil and laser surgery.
Topics: Administration, Topical; Brachytherapy; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorou | 1989 |
51 trials available for fluorouracil and Mouth Neoplasms
| Article | Year |
|---|---|
Prospective Phase II Open-Label Randomized Controlled Trial to Compare Mandibular Preservation in Upfront Surgery With Neoadjuvant Chemotherapy Followed by Surgery in Operable Oral Cavity Cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Chemothera | 2022 |
Normal BMI predicts the survival benefits of inductive docetaxel, cisplatin, and 5-fluorouracil in patients with locally advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Body Mass Index; Cisplatin; Docetaxel; Female; Fluorouracil; Humans; Induction Chemothe | 2020 |
Stathmin guides personalized therapy in oral squamous cell carcinoma.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamou | 2020 |
Phase III trial of docetaxel cisplatin 5-fluorouracil induction chemotherapy for resectable oral cancer suggests favorable pathological response as a surrogate endpoint for good therapeutic outcome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cisplatin; Docetaxel; Fluorouracil; Huma | 2021 |
A multicenter randomized phase II trial of hyperthermia combined with TPF induction chemotherapy compared with TPF induction chemotherapy in locally advanced resectable oral squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 2021 |
Effectiveness of incorporating cetuximab into docetaxel/cisplatin/fluorouracil induction chemotherapy and chemoradiotherapy for inoperable squamous cell carcinoma of the oral cavity: A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Ch | 2017 |
A two-arm multicenter phase II trial of one cycle chemoselection split-dose docetaxel, cisplatin and 5-fluorouracil (TPF) induction chemotherapy before two cycles of split TPF followed by curative surgery combined with postoperative radiotherapy in patien
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined | 2017 |
The role of NLRP3 inflammasome in 5-fluorouracil resistance of oral squamous cell carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Move | 2017 |
Efficacy of nimotuzumab combined with docetaxel-cisplatin-fluorouracil regimen in treatment of advanced oral carcinoma.
Topics: Aged; Aged, 80 and over; Alopecia; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemot | 2014 |
Preoperative chemotherapy in advanced resectable OCSCC: long-term results of a randomized phase III trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci | 2014 |
GDF15 is a potential predictive biomarker for TPF induction chemotherapy and promotes tumorigenesis and progression in oral squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinogenesis; Carc | 2014 |
[Grade IV myelosuppression after induction chemotherapy of TPF on oral cancer: clinical analysis of 29 cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Fluo | 2014 |
Hyperfractionated accelerated radiation therapy (HART) of 70.6 Gy with concurrent 5-FU/Mitomycin C is superior to HART of 77.6 Gy alone in locally advanced head and neck cancer: long-term results of the ARO 95-06 randomized phase III trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe | 2015 |
Neoadjuvant Chemotherapy for Locally Advanced Squamous Carcinoma of Oral Cavity: a Pilot Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe | 2015 |
Long-term results of a randomized phase III trial of TPF induction chemotherapy followed by surgery and radiation in locally advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 2015 |
Osteopontin Involves Cisplatin Resistance and Poor Prognosis in Oral Squamous Cell Carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Di | 2015 |
Organ preservation treatment using TPF-a pilot study in patients with advanced primary and recurrent cancer of the oral cavity and the maxillary sinus.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2009 |
TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, S | 2010 |
Phase I trial of split-dose induction docetaxel, cisplatin, and 5-fluorouracil (TPF) chemotherapy followed by curative surgery combined with postoperative radiotherapy in patients with locally advanced oral and oropharyngeal squamous cell cancer (TISOC-1)
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined | 2012 |
Survival following non surgical treatments for oral cancer: a single institutional result.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2012 |
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2013 |
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2013 |
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2013 |
Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2013 |
Accelerated hyperfractionated radiotherapy and concurrent protracted venous infusion chemotherapy in locally advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 2002 |
Multidisciplinary approach in advanced cancer of the oral cavity: outcome with neoadjuvant chemotherapy according to intention-to-treat local therapy. A phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci | 2002 |
Concurrent chemoradiotherapy with new platinum compound nedaplatin in oral cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Th | 2003 |
Primary chemotherapy in resectable oral cavity squamous cell cancer: a randomized controlled trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci | 2003 |
5-Fluorouracil and cisplatin in the treatment of advanced oral cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chi-Square Di | 2003 |
Postoperative chemotherapy with cisplatin and 5-fluorouracil in cancer of the oral cavity and the oropharynx--long-term results.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2003 |
Lack of survival advantage in patients with advanced, resectable squamous cell carcinoma of the oral cavity receiving induction chemotherapy with cisplatin (CDDP), docetaxel (TXT) and 5-fluorouracil (5FU).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Do | 2004 |
[Clinical trial of chemotherapy by superselective intra-arterial infusion of nedaplatin combined with radiotherapy for advanced oral cancer].
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; | 2005 |
A single-institute phase I/II trial combining nedaplatin dose escalation with a fixed dose of docetaxel for induction chemotherapy of oral squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Docetaxel; Dr | 2008 |
Polychemotherapy in squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cheek; Clinical Trials as Topic; | 1983 |
Clinical trials with oral Futraful (INN: Tegafur) in cancer of the head and neck.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Carcinoma, Adenoid Cystic; Car | 1981 |
Improved survival with preoperative chemotherapy followed by resection uncompromised by tumor response for advanced squamous cell carcinoma of the head and neck.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic | 1995 |
Neoadjuvant chemotherapy with carboplatin/5-fluorouracil in head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Combined Modali | 1993 |
[5-fluorouracil, cisplatin and retinol palmitate in the management of advanced cancer of the oral cavity. Phase II study].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diterpenes; Female; Fluorouracil; | 1993 |
Preoperative simultaneous chemoradiotherapy in locally advanced cancer of the oral cavity and oropharynx.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1997 |
[Inhibition of 5-fluorouracil-cisplatin-induced stomatitis by oral cryotherapy: use of an ice-bar containing fibrinolysin and deoxyribonuclease combine (Elase)].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Cryotherapy; Deoxyribonucleases; Drug Combinations | 1997 |
High rate of clinical complete response to weekly outpatient neoadjuvant chemotherapy in oral carcinoma patients using a new regimen of cisplatin, 5-fluorouracil, and bleomycin alternating with methotrexate and epirubicin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1999 |
[Results of a prospective randomized trial with induction chemotherapy for cancer of the oral cavity and tonsils].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Combined Moda | 1999 |
Intraarterial chemotherapy as neoadjuvant treatment of oral cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 1999 |
Preoperative induction chemotherapy followed by concurrent chemoradiotherapy in advanced carcinoma of the oral cavity and oropharynx.
Topics: Adult; Aged; Antineoplastic Agents; Cisplatin; Combined Modality Therapy; Feasibility Studies; Femal | 2000 |
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2001 |
[Evaluation of a combination chemotherapy with nedaplatin and 5-FU for oral cancers].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administ | 2001 |
[Combination chemotherapy with nedaplatin (CDGP) and 5-FU for oral cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administ | 2002 |
Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study.
Topics: Carcinoma, Squamous Cell; Fluorouracil; Follow-Up Studies; Humans; Mouth Neoplasms; Neoplasm Metasta | 1976 |
A randomized study of adjuvant chemotherapy for cancer of the upper aerodigestive tract.
Topics: Bleomycin; Carcinoma, Squamous Cell; Combined Modality Therapy; Cyclophosphamide; Fluorouracil; Head | 1986 |
Short-term results of the combination of cis-platinum, 5-fluorouracil and bleomycin in advanced upper aerodigestive tract cancers.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Clinical Trials as Topic; Comb | 1986 |
[Induction chemotherapy of carcinomas of the oral cavity and oropharynx. Feasibility study, levels and factors of response to treatment. Apropos of 135 cases].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma; Cisplatin; Clinic | 1987 |
[Long-term intravenous infusion of 5-fluorouracil combined with platidiam in local spread of squamous cell carcinoma of the oral cavity].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cl | 1989 |
Comparison of methotrexate and sequential methotrexate-5-fluorouracil for patients with recurrent squamous cell carcinoma of the oral cavity.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Female; Fluor | 1987 |
Combined therapy in advanced head and neck cancer: a randomized study.
Topics: Carcinoma, Squamous Cell; Clinical Trials as Topic; Cobalt Isotopes; Fluorouracil; Humans; Laryngeal | 1972 |
246 other studies available for fluorouracil and Mouth Neoplasms
| Article | Year |
|---|---|
Pharmacokinetic Characterization and Bioavailability Barrier for the Key Active Components of Botanical Drug Antitumor B (ATB) in Mice for Chemoprevention of Oral Cancer.
Topics: Alkaloids; Animals; Benzofurans; Biological Availability; Chemoprevention; Drugs, Chinese Herbal; Ma | 2021 |
FASN inhibition sensitizes metastatic OSCC cells to cisplatin and paclitaxel by downregulating cyclin B1.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclin B1; Fat | 2023 |
Exosomal-mediated transfer of APCDD1L-AS1 induces 5-fluorouracil resistance in oral squamous cell carcinoma via miR-1224-5p/nuclear receptor binding SET domain protein 2 (NSD2) axis.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Exosomes; Female; Fluorouracil; Histone-Lysine N-Methyl | 2021 |
Mechanism of sensitivity to cisplatin, docetaxel, and 5-fluorouracil chemoagents and potential erbB2 alternatives in oral cancer with growth differentiation factor 15 overexpression.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 9; Cell Line, Tumor; Cel | 2022 |
Propofol induces apoptosis and ameliorates 5‑fluorouracil resistance in OSCC cells by reducing the expression and secretion of amphiregulin.
Topics: Amphiregulin; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferati | 2022 |
[Analysis of curative effect of ultrasonic hyperthermia combined with TPF chemotherapy on 19 elderly with advanced oral squamous cell carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fluoroura | 2021 |
Transfersome Hydrogel Containing 5-Fluorouracil and Etodolac Combination for Synergistic Oral Cancer Treatment.
Topics: Administration, Cutaneous; Animals; Drug Carriers; Etodolac; Fluorouracil; Hydrogels; Liposomes; Mou | 2022 |
Extracellular
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Fluorouracil; Humans; Isopentenyl | 2022 |
Assessment of neoadjuvant chemotherapy with docetaxel, cisplatin, and fluorouracil in patients with oral cavity cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Fluorouracil; Head and Neck Ne | 2023 |
Evaluation of a docetaxel-cisplatin-fluorouracil-Au complex in human oral carcinoma cell line.
Topics: Carcinoma, Squamous Cell; Cell Line; Cisplatin; Docetaxel; Fluorouracil; Gold; Humans; Metal Nanopar | 2023 |
Buccal spray of standardized Berberis aristata extract causes tumour regression, chemoprotection and downregulation of inflammatory mediators in oral cancer hamster model.
Topics: Berberis; Cricetinae; Down-Regulation; Fluorouracil; Humans; Mouth Neoplasms; Plant Extracts | 2023 |
A novel intra-tumoral drug delivery carrier for treatment of oral squamous cell carcinoma.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Fluoroura | 2023 |
Enhancing the Effective Chemotherapy: The Combined Inhibition of Rhinacanthin-C, 5-Fluorouracil, and Etoposide on Oral Cancer Cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Etoposide; Fluorouracil; Humans; Mo | 2023 |
Cisplatin Induced the Expression of
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; | 2020 |
Assessment of Anti-carcinogenic Effect of Pomegranate in Oral Squamous Cell Carcinoma (Pre-clinical Study).
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Cell Proli | 2019 |
Preoperative intra-arterial chemotherapy with docetaxel, cisplatin, and peplomycin combined with intravenous chemotherapy using 5-fluorouracil for oral squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Fluo | 2020 |
MiR-92b as a marker for TPF induced chemotherapy response prediction and prognosis evaluation in with advanced oral squamous cell carcinoma patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; | 2020 |
Long-term outcomes of induction chemotherapy followed by chemoradiotherapy vs chemoradiotherapy alone as treatment of unresectable head and neck cancer: follow-up of the Spanish Head and Neck Cancer Group (TTCC) 2503 Trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Clinical Trials, Phase | 2021 |
Suppression of oral cancer by induction of cell cycle arrest and apoptosis using Juniperus communis extract.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dru | 2020 |
Antitumor Effects of the Novel Quinazolinone Holu-12: Induction of Mitotic Arrest and Apoptosis in Human Oral Squamous Cell Carcinoma CAL27 Cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Checkpoi | 2021 |
Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Cycle; Drug Delivery Sys | 2021 |
Downregulation of SELENBP1 enhances oral squamous cell carcinoma chemoresistance through KEAP1-NRF2 signaling.
Topics: 3' Untranslated Regions; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Down-Regulation; Dru | 2021 |
Decreased Annexin A1 expression enhances sensitivity to docetaxel, cisplatin and 5-fluorouracil combination induction chemotherapy in oral squamous cell carcinoma.
Topics: Annexin A1; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Doc | 2021 |
Bitter melon derived extracellular vesicles enhance the therapeutic effects and reduce the drug resistance of 5-fluorouracil on oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Checkpoi | 2021 |
Differential resistance to platinum-based drugs and 5-fluorouracil in p22phox-overexpressing oral squamous cell carcinoma: Implications of alternative treatment strategies.
Topics: Animals; Apoptosis; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Drug Resista | 2017 |
Prognostic importance of pathological response to neoadjuvant chemotherapy followed by definitive surgery in advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2017 |
FBXW7 expression affects the response to chemoradiotherapy and overall survival among patients with oral squamous cell carcinoma: A single-center retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle Proteins; Ce | 2017 |
Influence of a dosing-time on toxicities induced by docetaxel, cisplatin and 5-fluorouracil in patients with oral squamous cell carcinoma; a cross-over pilot study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Circadian Rhy | 2018 |
P16 positivity and regression grade predict survival after neoadjuvant radiotherapy of OSCC.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradiothera | 2018 |
Honokiol inhibits in vitro and in vivo growth of oral squamous cell carcinoma through induction of apoptosis, cell cycle arrest and autophagy.
Topics: Adenine; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Biphenyl Compounds; Carci | 2018 |
Investigation of cancer-associated fibroblasts and p62 expression in oral cancer before and after chemotherapy.
Topics: Actins; Antineoplastic Agents; Biomarkers, Tumor; Carboplatin; Carcinoma, Squamous Cell; Female; Fib | 2018 |
Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Chemoradiotherapy; | 2018 |
Glucocorticoids reduce chemotherapeutic effectiveness on OSCC cells via glucose-dependent mechanisms.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Doxorubicin; Drug Inte | 2019 |
Experience in Intra-arterial Chemotherapy using Two Protocols for the Treatment of OSCC over Two Decades at the University Hospital Vienna.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci | 2018 |
STAT3- and GSK3β-mediated Mcl-1 regulation modulates TPF resistance in oral squamous cell carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cisplatin; Dit | 2019 |
A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Fluor | 2019 |
Study of Thymidylate Synthase (TS) and Dihydropyrimidine Dehydrogenase (DPD) Expressions on 5-Fluorouracil in Oral Squamous Cell Carcinoma
Topics: Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; | 2019 |
Combination of 5-Florouracil and polyphenol EGCG exerts suppressive effects on oral cancer cells exposed to radiation.
Topics: Catechin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Therapy, Combination; Flu | 2019 |
Circulating miRNA-1290 as a potential biomarker for response to chemoradiotherapy and prognosis of patients with advanced oral squamous cell carcinoma: A single-center retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Differentiation; C | 2019 |
Elevated cyclin D1 expression is predictive for a benefit from TPF induction chemotherapy in oral squamous cell carcinoma patients with advanced nodal disease.
Topics: Aged; Apoptosis; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; | 2013 |
The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2013 |
Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling.
Topics: Apoptosis; Caffeic Acids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Syne | 2013 |
Evaluation of p53 protein as a prognostic factor for oral cancer surgery.
Topics: Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined C | 2013 |
Long-term stimulation of areca nut components results in increased chemoresistance through elevated autophagic activity.
Topics: Actins; Adenine; Antimetabolites, Antineoplastic; Antineoplastic Agents; Areca; Autophagy; Autophagy | 2014 |
Immunochemoradiotherapy for patients with oral squamous cell carcinoma: augmentation of OK-432-induced helper T cell 1 response by 5-FU and X-ray irradiation.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cytokines; Dendritic Cells; Female; Fluoro | 2013 |
Changes of oral microcirculation in chemotherapy patients: A possible correlation with mucositis?
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fema | 2014 |
A low Dicer expression is associated with resistance to 5-FU-based chemoradiotherapy and a shorter overall survival in patients with oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Biopsy; Carcinom | 2014 |
Sequential therapy of advanced buccal mucosa squamous cell carcinoma: three-year outcome.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; | 2014 |
Overexpression of fibronectin confers cell adhesion-mediated drug resistance (CAM-DR) against 5-FU in oral squamous cell carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Adhesi | 2014 |
Establishment of 5-fluorouracil-resistant oral squamous cell carcinoma cell lines with epithelial to mesenchymal transition changes.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cadherins; Carcinoma, Squamous Cell; Cell Line, | 2014 |
Survival and selected outcomes of older adults with locally advanced head/neck cancer treated with chemoradiation therapy.
Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Che | 2013 |
The BRCA2 gene is a potential molecular target during 5-fluorouracil therapy in human oral cancer cells.
Topics: Animals; Antimetabolites, Antineoplastic; BRCA2 Protein; Cell Line, Tumor; Cell Survival; CHO Cells; | 2014 |
Low PTEN expression is associated with worse overall survival in head and neck squamous cell carcinoma patients treated with chemotherapy and cetuximab.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; C | 2015 |
[18F]fluoro-2-deoxyglucose-positron emission tomography for the assessment of histopathological response after preoperative chemoradiotherapy in advanced oral squamous cell carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; | 2015 |
Sphere-forming-like cells (squamospheres) with cancer stem-like cell traits from VX2 rabbit buccal squamous cell carcinoma.
Topics: AC133 Antigen; Aldehyde Dehydrogenase 1 Family; Animals; Antigens, CD; Antineoplastic Agents; Carcin | 2014 |
Salvage surgery after local recurrence in patients with head and neck carcinoma treated with chemoradiotherapy or bioradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol | 2015 |
Osteopontin-integrin α(v)β(3) axis is crucial for 5-fluorouracil resistance in oral squamous cell carcinoma.
Topics: Aged; Aged, 80 and over; Animals; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; Female; Fluor | 2015 |
Role of induction chemotherapy for N3 head and neck squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2015 |
Complete response of huge buccal malignant melanoma in an octogenarian patient to arterial chemotherapy.
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Fluorouracil; Humans; | 2015 |
Dormancy activation mechanism of oral cavity cancer stem cells.
Topics: Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell T | 2015 |
Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinoma.
Topics: Aged; Apoptosis; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Drug Combinations; Drug Resistance, | 2015 |
Squamous Cell Carcinoma of the Head and Neck: Comparison of Diffusion-weighted MRI at b-values of 1,000 and 2,000 s/mm(2) to Predict Response to Induction Chemotherapy.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth | 2015 |
Self-Assembling Monomeric Nucleoside Molecular Nanoparticles Loaded with 5-FU Enhancing Therapeutic Efficacy against Oral Cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Prolifera | 2015 |
[Clinical Investigation of the Effects of Filgrastim BS1 on Neutropenia Following Oral Cancer Chemotherapy (TPF Therapy)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel; Female; Filgrastim; Fluo | 2015 |
[The Safety of Super-Selective Intra-Arterial Infusion Chemotherapy for Induction with Docetaxel, Cisplatin, and 5-Fluorouracil for Oral Cancer].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Docetaxel | 2015 |
Pre-treatment neutrophil to lymphocyte ratio predicts the chemoradiotherapy outcome and survival in patients with oral squamous cell carcinoma: a retrospective study.
Topics: Adult; Aged; C-Reactive Protein; Carcinoma, Squamous Cell; Disease-Free Survival; Female; Fluorourac | 2016 |
Induction chemotherapy before surgery for unresectable head and neck cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cetuxi | 2016 |
Metformin in combination with 5-fluorouracil suppresses tumor growth by inhibiting the Warburg effect in human oral squamous cell carcinoma.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Proliferation; Dru | 2016 |
MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; C | 2016 |
Synergistic effect of honokiol and 5-fluorouracil on apoptosis of oral squamous cell carcinoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Carcinoma, S | 2017 |
Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline.
Topics: 3' Untranslated Regions; Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; Arecoline; | 2016 |
Evaluating the efficacy and safety of continuous arterial infusion chemotherapy with cisplatin and 5-fluorouracil in treating oral cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Cisplatin; Female; Fluorouraci | 2016 |
Salivary Cytokine Levels and Oral Mucositis in Head and Neck Cancer Patients Treated With Chemotherapy and Radiation Therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Carcinoma; Carcinoma, | 2016 |
Hypoxia induces resistance to 5-fluorouracil in oral cancer cells via G(1) phase cell cycle arrest.
Topics: Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Hypoxia; Cell L | 2009 |
Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells.
Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Benzoquin | 2009 |
Combined evaluation of dihydropyrimidine dehydrogenase and thymidine phosphorylate mRNA levels in tumor predicts the histopathological effect of 5-fluorouracil-based chemoradiotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality T | 2009 |
RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletion.
Topics: Apoptosis; Basigin; Carcinoma, Squamous Cell; Cell Line, Tumor; Down-Regulation; Drug Resistance, Mu | 2009 |
[Clinical effects of concurrent chemoradiotherapy (hyperfractionation and cisplatin/5-fluorouracil) for patients with advanced oral squamous cell carcinoma].
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; | 2009 |
Preoperative radiochemotherapy in the treatment of advanced oral cancer: outcome of 276 patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cohort Studie | 2009 |
The effect of neoadjuvant therapy on the 5-fluorouracil metabolic and relative enzymes of oral squamous cell carcinoma.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcin | 2009 |
Vesnarinone downregulates CXCR4 expression via upregulation of Krüppel-like factor 2 in oral cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cisplatin; Down-Regulation; Flow Cy | 2009 |
Functional p53 status as a biomarker for chemotherapy response in oral-cavity cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Chemoth | 2010 |
5-Fluorouracil buccal tablets for locoregional chemotherapy of oral squamous cell carcinoma: formulation, drug release and histological effects on reconstituted human oral epithelium and porcine buccal mucosa.
Topics: Administration, Buccal; Animals; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cel | 2010 |
Rapid palliation of symptoms with platinum-based chemotherapy plus cetuximab in recurrent oral cancer: a case report.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2010 |
Comparison of four cisplatin-based radiochemotherapy regimens for nonmetastatic stage III/IV squamous cell carcinoma of the head and neck.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisp | 2011 |
Effects of lentinan alone and in combination with fluoropyrimidine anticancer agent on growth of human oral squamous cell carcinoma in vitro and in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2010 |
Up-regulation of survivin in oral squamous cell carcinoma correlates with poor prognosis and chemoresistance.
Topics: Antineoplastic Agents; Apoptosis Regulatory Proteins; Biomarkers, Tumor; Carcinoma, Squamous Cell; C | 2010 |
[Docetaxel as a component in the combined therapy of locally advanced squamous cell carcinoma of the glottis and oral cavity].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 2010 |
Honokiol: a promising small molecular weight natural agent for the growth inhibition of oral squamous cell carcinoma cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds | 2011 |
Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc | 2011 |
The bacterial protein azurin enhances sensitivity of oral squamous carcinoma cells to anticancer drugs.
Topics: Antineoplastic Agents; Apoptosis; Azurin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclin B1; Dru | 2011 |
3rd congress of the International Academy of Oral Oncology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell; Deoxycytidin | 2011 |
Overexpression of cIAP2 contributes to 5-FU resistance and a poor prognosis in oral squamous cell carcinoma.
Topics: Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2011 |
Differentiation-inducing factor-1 enhances 5-fluorouracil action on oral cancer cells inhibiting E2F1 and thymidylate synthase mRNAs accumulation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Cell Surviv | 2012 |
Radiochemotherapy induces a favourable tumour infiltrating inflammatory cell profile in head and neck cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplatin | 2012 |
Purification and biochemical characterization of a novel protein-tongue cancer chemotherapy resistance-associated protein1 (TCRP1).
Topics: Animals; Antibiotics, Antineoplastic; Antibody Specificity; Bleomycin; Carcinoma, Squamous Cell; Cel | 2012 |
Medium-term culture of primary oral squamous cell carcinoma in a three- dimensional model: effects on cell survival following topical 5-fluororacile delivery by drug-loaded matrix tablets.
Topics: Acrylates; Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cell Communication; | 2012 |
Antitumor efficacy of sequential treatment with docetaxel and 5-fluorouracil against human oral cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Dihydrouracil Dehydrogena | 2012 |
The effects of 5-fluorouracil alone and in combination with 13-cis retinoic acid and vitamin D3 on human oral squamous cell carcinoma lines.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cholecalciferol; Drug Com | 2012 |
Survival of patients with pathologic T0N+ oral and oropharyngeal cancer after neoadjuvant therapy and surgery: the minority report.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined C | 2013 |
Gastrostomy-site tumor recurrence is not always fatal.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brachytherapy; Carcinoma, Squamous Cell; Flu | 2003 |
[A case of large carcinoma of the tongue and mouth floor, in which chemotherapy using a combination of nedaplatin and 5-FU was effective].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma, Squamous Cell; Drug Admini | 2002 |
Quality of life 2-10 years after combined treatment for advanced oral and oropharyngeal cancer.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2002 |
Capecitabine induces rapid, sustained response in two patients with extensive oral verrucous carcinoma.
Topics: Antimetabolites, Antineoplastic; Biopsy; Capecitabine; Carcinoma, Verrucous; Deoxycytidine; Female; | 2003 |
[Chemosensitivity testing of oral and maxillofacial cancer with biopsy specimens].
Topics: Antineoplastic Agents; Biopsy; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Dose-Response Rel | 2002 |
[The clinical application and evaluation of combined chemotherapy in comprehensive treatment for oral squamous cell carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci | 2003 |
Enhanced susceptibility of oral squamous cell carcinoma cell lines to FAS-mediated apoptosis by cisplatin and 5-fluorouracil.
Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Arabidopsis Proteins; | 2003 |
[Combination chemotherapy with nedaplatin and 5-fluorouracil for oral squamous cell carcinomas].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration | 2003 |
Volumetric and histologic responses to radiotherapy or radiochemotherapy of metastatic cervical lymph nodes of oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplast | 2003 |
Clinical method of testing radiation-sensitizing agents in squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Cobalt Isotopes; Fluorouracil; Humans; Mouth Neoplasms; Nucleosides; Phary | 1963 |
INTRA-ARTERIAL INFUSION FOR HEAD AND NECK CANCER.
Topics: Antineoplastic Agents; Brain Neoplasms; Dactinomycin; Facial Neoplasms; Fluorouracil; Head and Neck | 1964 |
COMBINED CHEMOTHERAPY AND RADIATION THERAPY IN ADVANCED MALIGNANCIES.
Topics: Carcinoma, Bronchogenic; Cyclophosphamide; Female; Fluorouracil; Head and Neck Neoplasms; Humans; La | 1964 |
COMBINATION OF SURGERY AND CHEMOTHERAPY IN THE TREATMENT OF ORAL CANCER.
Topics: DNA; DNA, Neoplasm; Drug Therapy; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Neck Dissecti | 1964 |
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; H | 1965 |
SQUAMOUS CELL CARCINOMA OF ORAL CAVITY; INTRA-ARTERIAL INFUSION WITH FLUOROURACIL AND IDOXURIDINE.
Topics: Carcinoma; Carcinoma, Squamous Cell; Drug Therapy; Fluorouracil; Humans; Idoxuridine; Infusions, Int | 1965 |
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy | 2003 |
[Evaluation of quality of life of patients with oral squamous cell carcinoma. Comparison of two treatment protocols in a prospective study-first results].
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemoth | 2003 |
Clinical and pathological features of the murine AT-84 orthotopic model of oral cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models | 2003 |
Effect of 5-fluorouracil on G1 phase cell cycle regulation in oral cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Cycle Proteins; Cell | 2004 |
Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8.
Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Carcinoma; Cell | 2004 |
[Clinical study of the area under the blood concentration-time curve of targeting intra-arterial infusion chemotherapy with nedaplatin for primary oral cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma | 2004 |
Potentiation of induction of apoptosis by sequential treatment with cisplatin followed by 5-fluorouracil in human oral cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cispl | 2004 |
The synergistic cytotoxicity of cisplatin and taxol in killing oral squamous cell carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Squamous Cell; Cell Line, Tu | 2004 |
Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Sq | 2004 |
Concurrent chemoradiotherapy with pirarubicin and 5-fluorouracil for resectable oral and maxillary carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Combined Mo | 2004 |
Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Carcinoma, Squam | 2005 |
Enhanced Bax in oral SCC in relation to antitumor effects of chemotherapy.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Cell Line, T | 2005 |
Preoperative radiochemotherapy and radical resection for stages II-IV oral and oropharyngeal cancer: outcome of 222 patients.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy P | 2005 |
Preoperative radiochemotherapy and radical resection for stages II to IV oral and oropharyngeal cancer: grade of regression as crucial prognostic factor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Fe | 2005 |
Long-term survival in locally advanced oral cavity cancer: an analysis of patients treated with neoadjuvant cisplatin-based chemotherapy followed by surgery.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Ci | 2005 |
Silencing of the p53R2 gene by RNA interference inhibits growth and enhances 5-fluorouracil sensitivity of oral cancer cells.
Topics: Cell Line, Tumor; Cell Proliferation; Fluorouracil; Gene Silencing; Genes, p53; Genetic Therapy; Hum | 2005 |
Adenocarcinoma ex pleomorphic adenoma of the head and neck: Report of five cases.
Topics: Adenoma, Pleomorphic; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Docet | 2006 |
Orotate phosphoribosyl transferase mRNA expression in oral squamous cell carcinoma and its relationship with the dihydropyrimidine dehydrogenase expression and the clinical effect of 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Case-Control Studies; Chi-Square Distr | 2006 |
Retrospective analysis on prognostic impact of adjuvant chemotherapy in the patients with advanced and resectable oral squamous cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2006 |
The involvement of hypoxia-inducible factor-1alpha in the susceptibility to gamma-rays and chemotherapeutic drugs of oral squamous cell carcinoma cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous | 2007 |
[The role of a surgical method in combined and complex treatment of patients with squamous cell oral and oropharyngeal cancer].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 2007 |
Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Resistance, Neo | 2007 |
[Nedaplatin (NDP)-combination therapy (NDP/5-FU,NDP/S-1) for oral cancer].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2007 |
Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cisplatin; | 2007 |
[Clinical trial of chemotherapy by superselective intra-arterial infusion of nedaplatin (CDGP) and 5-FU with concurrent radiotherapy for advanced oral cancer].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; D | 2007 |
[Neoadjuvant radiochemotherapy for squamous cell carcinoma of the oral cavity].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci | 2008 |
Intra-arterial chemoradiotherapy for locally advanced oral cavity cancer: analysis of therapeutic results in 134 cases.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2008 |
Pharmacokinetic characteristics and anticancer effects of 5-fluorouracil loaded nanoparticles.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Line, Tumor; Colonic Neopla | 2008 |
Intensive combination chemotherapy for cancer of the oral cavity.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Evaluation; Drug Therapy, Combinati | 1983 |
5-fluorouracil modulation of dihydrofolate reductase RNA levels in methotrexate-resistant KB cells.
Topics: Carcinoma; Cell Division; Cell Line; Clone Cells; Fluorouracil; Gene Amplification; Humans; Kinetics | 1983 |
[Clinical study related to the concentration of Futraful suppository in organs].
Topics: Female; Fluorouracil; Humans; Jaw Neoplasms; Male; Mouth Neoplasms; Suppositories; Tegafur; Tissue D | 1983 |
Combination of 5-fluoro-uracil and Co60 irradiation in the treatment of carcinoma of the oro-facial region. A follow-up investigation of 30 patients.
Topics: Adult; Aged; Cobalt Radioisotopes; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Stud | 1983 |
A nontoxic adjuvant treatment for advanced head and neck cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fluoroura | 1983 |
Oral and pharyngeal cancer: combined approach for multimodal therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cobalt Radioisotopes; Combined Modality | 1983 |
Carcinoma of the maxillary sinus with eosinophilia. Report of a case.
Topics: Carcinoma, Squamous Cell; Eosinophilia; Eosinophils; Fluorouracil; Humans; Leukocyte Count; Male; Ma | 1981 |
[Treatment of malignant tumors of the oral cavity].
Topics: Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Methotrexate; Mouth Neoplasms | 1980 |
[Variations of serum BuChe activity during C M F therapy].
Topics: Breast Neoplasms; Butyrylcholinesterase; Cholinesterases; Cyclophosphamide; Drug Therapy, Combinatio | 1981 |
A biochemical evaluation of oral squamous cell carcinoma growth by measurement of specific activity of succinate dehydrogenase in the subrenal capsule assay.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Colorimetry; Coloring Agents; D | 1995 |
[Accelerated hyperfractionated radiotherapy combined with simultaneous chemotherapy in locally advanced pharyngeal and oral carcinomas].
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1994 |
Influence of inductive chemoradiotherapy on salivary polymorphonuclear leukocyte (SPMN) functions in oral cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Candidiasis, Oral; Carcinoma, Squamous | 1994 |
[Method for daily administration of low-dose CDDP and 5-FU combined with radiotherapy for oral squamous cell carcinoma].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined | 1995 |
Influence of cisplatinum and 5-fluorouracil on the oral mucosa.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cisplatin; Fluorour | 1994 |
[A retrospective study on the importance of preoperative control in the prognosis of spinocellular carcinoma of the oral cavity].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Cobalt Radioisotopes; Combined Modality Therapy; F | 1994 |
Histopathological findings after preoperative chemo-radiotherapy in oral and oropharyngeal carcinoma. A study of 28 resected specimens.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 1993 |
In vitro antitumour activity of cis- and trans-5-fluoro-5,6-dihydro-6-alkoxy-uracils; effects on thymidylate synthesis.
Topics: Carcinoma, Squamous Cell; Cell Division; Deoxyuridine; DNA, Neoplasm; Drug Screening Assays, Antitum | 1993 |
p53 overexpression and mutation, chemoresistance and patient survival in oral and maxillofacial squamous cell carcinoma.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Sq | 1997 |
Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Dinoprostone; Fluorouracil; Humans; | 1997 |
Intranodal injection of anticancer drugs into fixed cervical metastatic lymph nodes.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C | 1997 |
Expression of platelet-derived endothelial cell growth factor in oral and oropharyngeal carcinoma.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Female; Fluorouraci | 1998 |
[Results of organ-preserving and reconstructive surgery of the mandible in patients with cancer of the oral cavity].
Topics: Adult; Alveolar Process; Antimetabolites, Antineoplastic; Combined Modality Therapy; Fluorouracil; H | 1998 |
p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibi | 1998 |
Expression of hMSH2 correlates with in vitro chemosensitivity to CDDP cytotoxicity in oral and oropharyngeal carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; DNA-Bind | 1998 |
5-Fluorouracil-induced apoptosis in cultured oral cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Dose-Respo | 2000 |
Successful treatment of oral squamous cell carcinoma with intralesional fluorouracil in a Malayan tapir (Tapirus indicus).
Topics: Animals; Antimetabolites, Antineoplastic; Biopsy; Carcinoma, Squamous Cell; Cephalosporins; Fluorour | 2000 |
[5-FU concentration in the serum and the tumor tissue after administration of UFT 200 mg/day to patients over 80 years of age with oral cancer].
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Proto | 2000 |
[Chemotherapy with nedaplatin for an oral floor cancer patient undergoing chronic hemodialysis].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administration | 2000 |
[A case report of radiation-induced cancer of the buccal mucosa, effectively treated with CF therapy].
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy P | 2001 |
Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Erythropoietin; Female; Fl | 2001 |
Influence of chemotherapy on endosteal implant survival and success in oral cancer patients.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco | 2001 |
Long-term complete remission of oral cancer after anti-neoplastic chemotherapy as single treatment modality: role of local chemotherapy.
Topics: Aged; Antineoplastic Agents; Cisplatin; Fluorodeoxyglucose F18; Fluorouracil; Humans; Infusions, Int | 2002 |
[Non-randomized clinical study comparing chemotherapy plus radiotherapy with radiotherapy alone in neoadjuvant therapy for oral cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 2002 |
Management of oral and pharyngeal cancer: a multidisciplinary approach.
Topics: Bleomycin; Carcinoma, Squamous Cell; Fluorouracil; Humans; Lymphatic Metastasis; Mouth Floor; Mouth | 1975 |
Kinetically-based multiple drug treatment for advanced head and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neopla | 1975 |
The role of chemotherapy in the management of cancer of the head and neck: a review.
Topics: Bleomycin; Dinitrochlorobenzene; Doxorubicin; Drug Therapy, Combination; Fluorouracil; Head and Neck | 1975 |
[Radiotherapy of inoperable orofacial squamous epithelial carcinomas following pharmacologically induced partial synchronization].
Topics: Aged; Carcinoma, Squamous Cell; Cell Movement; DNA; Fluorouracil; Humans; Male; Mouth Neoplasms; Neo | 1975 |
Irradiation treatment of inoperable squamous cell carcinomas of the oral cavity and oropharynx after partial synchronisation.
Topics: Bleomycin; Carcinoma, Squamous Cell; Fluorouracil; Mitosis; Mouth Neoplasms; Pharyngeal Neoplasms; T | 1976 |
Cell-kinetical analyses of squamous cell carcinomas of the oral region and the effect of a combined therapy of 5 fluorouracil and irradiation. A contribution to the discussion about tumorcell-synchronization.
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Cell Division; Cell Movement; Cytological Techniqu | 1977 |
Chemotherapy for oral malignant disease.
Topics: Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Fluorouracil; Humans; Hydroxyurea; Inje | 1979 |
[Long-term results of synchronized radiotherapy in inoperable orofacial squamous cell carcinoma].
Topics: Bleomycin; Carcinoma, Squamous Cell; Drug Evaluation; Fluorouracil; Humans; Mouth Neoplasms; Pharyng | 1978 |
Current status of regional arterial infusion chemotherapy.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carotid Arteries; Catheterization; | 1975 |
[Synchronization of squamous-cell carcinoma cell populations by 5-fluorouracil in radiation therapy].
Topics: Aged; Carcinoma, Squamous Cell; Cell Cycle; Fluorouracil; Humans; In Vitro Techniques; Interphase; L | 1979 |
[Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil].
Topics: Aged; Carcinoma, Basal Cell; Drug Therapy, Combination; Female; Fluorouracil; Humans; Keratosis; Leu | 1978 |
[Contribution to the radiation therapy of malignant tumors in the regions of the head and neck using the synchronization effects of fluorouracil (author's transl)].
Topics: Adult; Aged; Esophageal Neoplasms; Female; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal | 1978 |
Combined chemotherapy and cryosurgery for oral cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cryosurgery; Drug Therapy, Combination | 1975 |
Chemosensitivity of salivary gland and oral cancer cell lines.
Topics: Cantharidin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Salivary Gland Neopla | 1992 |
[Fundamental study of subrenal capsule assay by measuring specific activity of succinate dehydrogenase].
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Fluorouracil; Male; | 1992 |
[Effectiveness of cisplatin with continuous infusion of 5-fluorouracil in neoadjuvant chemotherapy of carcinoma of the oral cavity].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 1992 |
[The clinical effect of cisplatin and 5-FU infusion in oral cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, | 1992 |
Heavy water enhances the antineoplastic effect of 5-fluoro-uracil and bleomycin in nude mice bearing human carcinoma.
Topics: Adenocarcinoma; Animals; Bleomycin; Carcinoma, Squamous Cell; Colonic Neoplasms; Deuterium; Drug Syn | 1990 |
[Speech intelligibility in tongue and mouth-floor cancer patients who received surgical excisions after induction therapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; F | 1990 |
[Cardiac toxicity of 5-fluorouracil. Two cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Carcinoma, Squamous Cell; Cispl | 1991 |
Combined modality treatment of advanced cancers of the oral cavity and oropharynx.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1991 |
Gustatory impairment and salivary gland pathophysiology in relation to oral cancer treatment.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cobalt Radioisotopes; Female; Fluorouracil; Humans; Male; Mid | 1990 |
Optimization of preoperative chemotherapy by ultrasound. Follow-up in tumours of the oral cavity and oropharyngeal region.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Female; Fluorouracil; Follow | 1990 |
Treatment of oral squamous cell carcinoma with simultaneous chemotherapy and radiation: results and surgical implications.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Co | 1990 |
[T4 carcinoma of the oral cavity responsive to bilateral 5-FU intra-arterial infusion and simultaneous irradiation].
Topics: Catheterization; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Male; M | 1990 |
[Induction chemotherapy in cancer of the upper respiratory and digestive tract. Preliminary results of the protocol combining cisplatin, 5-fluorouracil and bleomycin (CFB)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Comb | 1985 |
Pretreatment with chemotherapy in patients with advanced head and neck cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin; Cycl | 1985 |
Inhibited methionine incorporation in human squamous carcinomas of the oral cavity as a measure for response to 5-fluorouracil.
Topics: Carcinoma, Squamous Cell; Cell Division; Fluorouracil; Humans; Methionine; Mouth Neoplasms; Neoplasm | 1989 |
Response to preoperative concomitant radiochemotherapy with mitomycin C and 5-fluorouracil in advanced head and neck cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1989 |
Histological grading of therapy induced regression in squamous cell carcinomas of the oral cavity. A morphological and immunohistochemical study.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; H | 1989 |
[Combination effect of UFT and gamma-irradiation against nude mice transplanted KB cells].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fluorouracil; Ga | 1989 |
[Synchronization therapy as a palliative measure in incurable head and neck tumors].
Topics: Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Head and | 1985 |
[Preoperative chemotherapy for head and neck cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Ne | 1985 |
[Toxicity of cisplatin with continuous infusion of 5-fluorouracil in neoadjuvant chemotherapy of carcinoma of the oral cavity].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Fe | 1989 |
[Induction chemotherapy with Cis DDP-5FU in cancers of the upper respiratory and digestive tract after 70 years of age].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C | 1989 |
[Treatment of head and neck neoplasms].
Topics: Cisplatin; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neopl | 1989 |
[Preoperative radiochemotherapy in advanced oral and oropharyngeal carcinoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Moda | 1987 |
[The clinical and histological effect of preoperative combination chemotherapy with low dose MTX.5-FU in oral cancer].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Drug Administ | 1988 |
[A case report of verrucous carcinoma of the lower molar region, effectively treated with preoperative irradiation and continuous intra-arterial infusion of fluorouracil].
Topics: Aged; Carcinoma, Papillary; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arteri | 1987 |
Allergic reaction to 5-fluorouracil infusion.
Topics: Angioedema; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Dru | 1986 |
Induction chemotherapy with cis-platinum and 5-fluorouracil for squamous cell carcinoma of the head and neck.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1986 |
Combined cryosurgical, chemotherapeutic, and radiotherapeutic management of T1-4N0M0 oral cavity cancers.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cobalt Radioi | 1985 |
Carcinoma of the tongue and floor of the mouth. Preliminary results of a multidisciplinary approach.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous | 1985 |
[An evaluation of multi-disciplinary treatment combined with intra-arterial chemotherapy of head and neck cancer].
Topics: Brachytherapy; Combined Modality Therapy; Fluorouracil; Head and Neck Neoplasms; Humans; Infusions, | 1985 |
Salvage of stage IV intraoral squamous cell carcinomas with preoperative 5-fluorouracil.
Topics: Administration, Topical; Adult; Aged; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; F | 1986 |
Combined chemotherapy, cryosurgery, and radiotherapy/surgery for oral cancer.
Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Cryosurgery; Cyclophosphamide; Female; Fluorour | 1985 |
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Hum | 1971 |
Factors influencing the success of arterial infusion chemotherapy for cancer of the head and neck.
Topics: Age Factors; Aged; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 1972 |
Intra-arterial infusion--an adjuvant to the treatment of oral carcinoma.
Topics: Adult; Aged; Carotid Artery, External; Catheterization; Evaluation Studies as Topic; Floxuridine; Fl | 1972 |
[Intra-arterial chemotherapy of head and neck tumors: statistical study of 129 cases treated at the Institut Gustave Roussy].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Facial Neoplasms | 1973 |
Protracted intra-arterial chemotherapy with sequential courses of antimitotics and hydrogen peroxyde in the treatment of head and neck tumors.
Topics: Antineoplastic Agents; Catheterization; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; | 1969 |
[Combination of chemotherapy and electrocoagulation in the treatment of gingival cancers].
Topics: Electrocoagulation; Fluorouracil; Gingival Diseases; Humans; Methotrexate; Mouth Neoplasms; Neoplasm | 1968 |
Triple drug intra-arterial infusion combined with x-ray therapy and surgery for head and neck cancer.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fluorouracil; Head and N | 1974 |
[Radiotherapy of synchronized tumors].
Topics: Cobalt Isotopes; Fluorouracil; Humans; Mitosis; Mouth Neoplasms; Radioisotope Teletherapy | 1972 |
Histologic evaluation of treatment of epidermoid carcinoma in the oral cavity with methotrexate and 5-fluorouracil.
Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Fluorouracil; Humans; Injections, Intra- | 1974 |
Results in 169 patients with cancer of the head and neck treated by intra-arterial infusion therapy.
Topics: Antineoplastic Agents; Brachial Artery; Brachiocephalic Trunk; Carcinoma, Squamous Cell; Carotid Art | 1972 |
[Oral, florid papillomatosis].
Topics: Adrenal Cortex Hormones; Aged; Female; Fluorouracil; Humans; Injections, Intramuscular; Lip Neoplasm | 1973 |
Results in fifty cases of advanced squamous cell carcinoma of the head and neck treated by intravenous chemotherapy.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Combinations; Epiglottis; Female; Fluo | 1973 |
[Synchronized radiotherapy in malignant tumors. Theoretical bases and clinical results].
Topics: Aged; Animals; Cell Division; Evaluation Studies as Topic; Fluorouracil; Humans; Mice; Mouth Neoplas | 1973 |
Regional chemotherapy of cancer of the head and neck.
Topics: Antineoplastic Agents; Carcinoma; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; Head; Head | 1966 |
[Therapy of malignant tumor of the head and neck region].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Mi | 1971 |
Arginine requirement for late mRNA transcription of vaccinia virus in KB cells.
Topics: Arginine; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; DNA Replication; | 1971 |
Treatment of advanced cancer of the head and neck.
Topics: Fluorouracil; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Mouth Neoplasms; Nasopharyngeal | 1970 |
Pre-irradiation 5-fluorouracil infusion in advanced head and neck carcinomas.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cobalt Isotopes; Female; Fluorouracil; Humans; Injections, In | 1971 |
[Continuous intra-arterial infusion of 5-fluorouracil in oral cancer].
Topics: Adult; Aged; Animals; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Injections, Intra-Arte | 1967 |
Sequential chemotherapy and radiation therapy of buccal mucosa carcinoma in South India. Methods and preliminary results.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Cheek; Cobalt Isotopes; Deoxyuridine; | 1968 |
Intra-arterial infusion therapy for oral cancer.
Topics: Catheterization; Fluorouracil; Humans; Injections, Intra-Arterial; Methods; Methotrexate; Mouth Neop | 1968 |
[218 cases of prolonged polychemotherapy in advanced cancer (especially bronchopulmonary). Modalities and results].
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neop | 1968 |
Combined intra-arterial infusion and radiotherapy for the treatment of advanced cancer of the head and neck.
Topics: Aged; Brain Neoplasms; Carcinoma, Squamous Cell; Esophageal Neoplasms; Fluorouracil; Follow-Up Studi | 1969 |
The use of parenteral 5-fluorouracil in solid tumours. A preliminary report.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Female; Fluorouracil; Gastrointestinal Neoplasms; Genital | 1969 |