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fluorouracil and Moniliasis, Oral

fluorouracil has been researched along with Moniliasis, Oral in 8 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"After perioperative adjuvant chemotherapy of a sigma-adenocarcinoma with 400 mg peptichemio and 500 mg 5-fluorouracil a 61-year-old woman developed a severe intoxication: myelosuppression with pancytopenia, gastroenteritis and ulcerative proctitis, toxic hepato- and myocardiopathy, impaired renal function and alopecia."7.66[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)]. ( Gasser, RW; Schmalzl, F, 1982)
"Treatment with fluconazole was ineffective, but amphotericin B was curative."5.29Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996)
"Forty-five consecutive breast cancer patients, eligible for adjuvant CT with cyclophosphamide, epirubicin or methotrexate, and 5-fluorouracil were followed before, during, 6 months and 1 year after CT and were compared to a control group of 31 breast cancer patients not receiving adjuvant CT."3.74Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients. ( Bergmann, OJ; Brünner, N; Jensen, SB; Mouridsen, HT; Nauntofte, B; Reibel, J, 2008)
" This prospective cohort study investigated orofacial complications of combination chemotherapy (cyclophosphamide, methotrexate, fluorouracil, vincristine, and prednisone) in women with breast cancer."3.68Orofacial complications of chemotherapy for breast cancer. ( McCarthy, GM; Skillings, JR, 1992)
"After perioperative adjuvant chemotherapy of a sigma-adenocarcinoma with 400 mg peptichemio and 500 mg 5-fluorouracil a 61-year-old woman developed a severe intoxication: myelosuppression with pancytopenia, gastroenteritis and ulcerative proctitis, toxic hepato- and myocardiopathy, impaired renal function and alopecia."3.66[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)]. ( Gasser, RW; Schmalzl, F, 1982)
"Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen."1.37Oral candidiasis mimicking tongue cancer. ( Hasegawa, S; Hashikawa, K; Nibu, K; Otsuki, N; Saito, M; Shibata, T; Tahara, S; Yamashita, D, 2011)
"Treatment with fluconazole was ineffective, but amphotericin B was curative."1.29Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertolini, M1
Ranjan, A1
Thompson, A1
Diaz, PI1
Sobue, T1
Maas, K1
Dongari-Bagtzoglou, A1
Jensen, SB1
Mouridsen, HT1
Bergmann, OJ1
Reibel, J1
Brünner, N1
Nauntofte, B1
Shibata, T1
Yamashita, D1
Hasegawa, S1
Saito, M1
Otsuki, N1
Hashikawa, K1
Tahara, S1
Nibu, K1
Gasser, RW1
Schmalzl, F1
Ueta, E1
Osaki, T1
Yoneda, K1
Yamamoto, T1
Umazume, M1
Arranz-Caso, JA1
Lopez-Pizarro, VM1
Gomez-Herruz, P1
García-Altozano, J1
Martinez-Martinez, J1
Ottolenghi, F1
Andreassi, L1
Sbano, E1
Fimiani, M1
McCarthy, GM1
Skillings, JR1

Other Studies

8 other studies available for fluorouracil and Moniliasis, Oral

ArticleYear
Candida albicans induces mucosal bacterial dysbiosis that promotes invasive infection.
    PLoS pathogens, 2019, Volume: 15, Issue:4

    Topics: Animals; Antimetabolites; Candida albicans; Candidiasis, Oral; Disease Models, Animal; Dysbiosis; Fe

2019
Oral mucosal lesions, microbial changes, and taste disturbances induced by adjuvant chemotherapy in breast cancer patients.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2008, Volume: 106, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Al

2008
Oral candidiasis mimicking tongue cancer.
    Auris, nasus, larynx, 2011, Volume: 38, Issue:3

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Candidiasis, Oral;

2011
[Severe intoxication after combined chemotherapy of a sigma-adenocarcinoma with peptichemio and 5-fluorouracil (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1982, May-15, Volume: 132, Issue:9

    Topics: Adenocarcinoma; Alopecia; Candidiasis, Oral; Diarrhea; Female; Fluorouracil; Hepatomegaly; Humans; M

1982
Influence of inductive chemoradiotherapy on salivary polymorphonuclear leukocyte (SPMN) functions in oral cancer.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1994, Volume: 23, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Candidiasis, Oral; Carcinoma, Squamous

1994
Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole.
    Diagnostic microbiology and infectious disease, 1996, Volume: 24, Issue:3

    Topics: Administration, Inhalation; Amphotericin B; Biopsy; Candidiasis; Candidiasis, Oral; Diabetes Complic

1996
[Diffuse chronic mucocutaneous candidiasis: Effects of antimycotics in vitro].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1975, Volume: 26, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Cutaneous; Candidiasis, Oral; Child; Chroni

1975
Orofacial complications of chemotherapy for breast cancer.
    Oral surgery, oral medicine, and oral pathology, 1992, Volume: 74, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Candidiasis, Oral; Chi-Squa

1992