fluorouracil has been researched along with Middle Ear Inflammation in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most effective treatment of middle ear cholesteatoma is surgical excision, and there is no medical treatment for this disease." | 1.51 | Evaluation of the Effect of Diclofenac Sodium and 5-Fluourasil in a 3D Cholesteatoma Cell Culture Model. ( Bayraktar, H; Demir, D; Duman, BO; Guven, M; Halbutogulları, ZSU; Kara, A; Kara, RO; SinanYilmaz, M; Yazır, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kara, A | 1 |
| Duman, BO | 1 |
| Yazır, Y | 1 |
| SinanYilmaz, M | 1 |
| Halbutogulları, ZSU | 1 |
| Demir, D | 1 |
| Kara, RO | 1 |
| Bayraktar, H | 1 |
| Guven, M | 1 |
1 other study available for fluorouracil and Middle Ear Inflammation
| Article | Year |
|---|---|
Evaluation of the Effect of Diclofenac Sodium and 5-Fluourasil in a 3D Cholesteatoma Cell Culture Model.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Culture Techniques; Cholesteatoma, M | 2019 |