fluorouracil has been researched along with Microglossia in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Capecitabine is a prodrug of fluorouracil." | 1.35 | Focal acral hyperpigmentation in a patient undergoing chemotherapy with capecitabine. ( Alonso, V; Calduch, L; Jordá, E; Martín, JM; Pinazo, MI; Villalón, G, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Villalón, G | 1 |
| Martín, JM | 1 |
| Pinazo, MI | 1 |
| Calduch, L | 1 |
| Alonso, V | 1 |
| Jordá, E | 1 |
| Dörr, W | 1 |
| Bässler, S | 1 |
| Reichel, S | 1 |
| Spekl, K | 1 |
2 other studies available for fluorouracil and Microglossia
| Article | Year |
|---|---|
Focal acral hyperpigmentation in a patient undergoing chemotherapy with capecitabine.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Deoxycytidine; Dermoscopy; Female; | 2009 |
Reduction of radiochemotherapy-induced early oral mucositis by recombinant human keratinocyte growth factor (palifermin): experimental studies in mice.
Topics: Animals; Cisplatin; Dose Fractionation, Radiation; Drug Evaluation, Preclinical; Fibroblast Growth F | 2005 |