fluorouracil has been researched along with Microbial Superinvasion in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 61-year-old woman with metastatic breast cancer who was undergoing treatment with capecitabine developed erythema, fissuring, and erosions over both hands and feet, consistent with HFS." | 8.87 | Capecitabine-induced hand-foot syndrome complicated by pseudomonal superinfection resulting in bacterial sepsis and death: case report and review of the literature. ( Baker, SG; Cotliar, JA; Gunawardane, ND; Hoesly, FJ, 2011) |
| "A 61-year-old woman with metastatic breast cancer who was undergoing treatment with capecitabine developed erythema, fissuring, and erosions over both hands and feet, consistent with HFS." | 4.87 | Capecitabine-induced hand-foot syndrome complicated by pseudomonal superinfection resulting in bacterial sepsis and death: case report and review of the literature. ( Baker, SG; Cotliar, JA; Gunawardane, ND; Hoesly, FJ, 2011) |
| "The risk of superinfection following routine abdominal drainage after major surgery is debated." | 1.28 | Implantable drainage after major abdominal surgery in compromised patients. ( Andersson, R; Bengmark, S; Holmberg, A; Jeppsson, B, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoesly, FJ | 1 |
| Baker, SG | 1 |
| Gunawardane, ND | 1 |
| Cotliar, JA | 1 |
| Andersson, R | 1 |
| Jeppsson, B | 1 |
| Holmberg, A | 1 |
| Bengmark, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II, Randomised Controlled Trial to Evaluate the Efficacy and Safety of Moisturising Creams With or Without Palm-oil-derived Vitamin E Concentrate in Addition to Urea-based Cream or Urea-based Cream Alone in Capecitabine-associated Palmar-Plantar E[NCT05939726] | 90 participants (Anticipated) | Interventional | 2023-05-16 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Microbial Superinvasion
| Article | Year |
|---|---|
Capecitabine-induced hand-foot syndrome complicated by pseudomonal superinfection resulting in bacterial sepsis and death: case report and review of the literature.
Topics: Antimetabolites, Antineoplastic; Bacteremia; Breast Neoplasms; Capecitabine; Deoxycytidine; Fatal Ou | 2011 |
1 other study available for fluorouracil and Microbial Superinvasion
| Article | Year |
|---|---|
Implantable drainage after major abdominal surgery in compromised patients.
Topics: Abdominal Neoplasms; Adult; Aged; Bacterial Infections; Drainage; Female; Fluorouracil; Humans; Immu | 1990 |